Relationship between tone perception and cognitive functions of attention and working memory among normal native speakers of Cantonese

This study investigated the relationship between tone perception and cognitive capabilities of attention and working memory in the auditory and visual domains among normal speakers of Cantonese. Fifteen near-mergers (i.e. poor perception of T4/T6 but good production of all lexical tones in Cantonese), and 20 controls (i.e. good perception and production of tones) participated in this study. The Test of Everyday Attention (TEA), the Attention Network Test (ANT), the test of attentional shifting, the digit span backward test and WAIS-IV visual working memory subtests were implemented. Results showed that Near-mergers performed significantly poorer than Controls in divided attention of both auditory and visual domains. Furthermore, the discrimination latency was found to relate to auditory attention and visual working memory. This suggested a modality independent relationship between tone perception and cognitive abilities. It is hypothesized that attention and working memory play a role in modulating the processing speed of tone perception.published_or_final_versionSpeech and Hearing SciencesBachelorBachelor of Science in Speech and Hearing Science

Atenuation of scopolamine-induced deficits in navigational memory performance in rats by bis(7)-tacrine,a novel dimeric AChE inhibitor

目的：研究他克林的雙體衍生物雙（７） 他克林對東莨菪堿引起的大鼠記憶障礙的影響．方法：采用大鼠Ｍｏｒｉｓ水迷宮固定平臺的程序研究空間記憶．以他克林為對照藥．結果：東莨菪堿（０３ｍｇ·ｋｇ－１，ｉｐ）使大鼠到達平臺的潛伏期明顯長于生理鹽水對照組．雙（７） 他克林（０３５μｍｏｌ·ｋｇ－１，ｉｇ或ｉｐ）和他克林（８５２μｍｏｌ·ｋｇ－１ｉｇ；４２６μｍｏｌ·ｋｇ－１ｉｐ）均可對抗東莨菪堿導致的空間記憶障礙；在灌胃及腹腔注射途徑下，雙（７） 他克林的效價，分別強于他克林２４及１２倍．結論：雙（７） 他克林明顯改善東莨菪堿導致的空間記憶障礙，其作用強于他克林