Bio-Inspired Aggregation Control of Carbon Nanotubes for Ultra-Strong Composites

High performance nanocomposites require well dispersion and high alignment of the nanometer-sized components, at a high mass or volume fraction as well. However, the road towards such composite structure is severely hindered due to the easy aggregation of these nanometer-sized components. Here we demonstrate a big step to approach the ideal composite structure for carbon nanotube (CNT) where all the CNTs were highly packed, aligned, and unaggregated, with the impregnated polymers acting as interfacial adhesions and mortars to build up the composite structure. The strategy was based on a bio-inspired aggregation control to limit the CNT aggregation to be sub 20--50 nm, a dimension determined by the CNT growth. After being stretched with full structural relaxation in a multi-step way, the CNT/polymer (bismaleimide) composite yielded super-high tensile strengths up to 6.27--6.94 GPa, more than 100% higher than those of carbon fiber/epoxy composites, and toughnesses up to 117--192 MPa. We anticipate that the present study can be generalized for developing multifunctional and smart nanocomposites where all the surfaces of nanometer-sized components can take part in shear transfer of mechanical, thermal, and electrical signals

Design and Implementation of Remote Server monitoring system

网络和服务器是信息化应用的基础，对中小型网络而言，服务器是网络中最主要的设备之一，提高管理与维护水平是保障网络与服务器的正常运行的重要途径，其中，对服务器的监控是整个网络监控系统中的重要环节。通过对服务器的监控可以更好地掌握目前的网络运行状态，及时判断服务器在运行过程中出现的各种异常，并为判断网络异常引发的原因提供重要的依据。现有的网络监控系统大多基于大型网络系统专门定制开发，庞大而复杂，并不符合中小型网络的实际需求。本文在分析中小网络的实际情况的基础上，提出建立一种通用的、跨平台、易用的远程服务器监控系统。在不改变原有网络环境和另外增加对管理人员的培训的情况下，直观、方便地对服务器进行远程监...Network and server are the foundation of informationization. To SMEs network, server is the primary device. To improve the management and maintenance is also an important way to keep network and server running normally. Server monitoring is the key point in network monitoring system. Besides the mastery of the server condition, timely estimation of problems occurring in process, it is also able to...学位：工程硕士院系专业：信息科学与技术学院计算机科学系_计算机应用技术学号：X20034305

校园路灯设计浅说

校园路灯照明效果对于良好校园气氛的营造以及校园安全的保障起着重要的作用,文章以参加我校校区路灯改造及马来西亚分校建设的经验谈起,从校园路灯照度、路灯布设方式、光源种类、供电方式及电缆线路、安全接地系统以及节能控制等方面选型设计谈谈校园室外路灯优化设计

建筑电气施工管理若干要点探究

随着建筑的发展,电气施工管理越来越重要。就目前的情况而言,电气工程涉及到的施工技术较为复杂、施工程序也较为繁琐,要想不断地提高现有的电气施工质量,就要不断地完善管理制度,科学管理。该文针对民用建筑方面讨论建筑电气施工管理若干要点,并对这些管理要点做出了深入地分析

RC-RNase-induced cell death in estrogen receptor positive breast tumors through down-regulation of Bcl-2 and estrogen receptor

[[abstract]]RC-RNase exerts anti-cancer effects on many tumors. However, the mechanisms by which RC-RNase induces cytotoxicity in different tumor cells are unclear. Currently, estrogen receptor (ER)-positive and negative breast tumors are treated with RC-RNase. Our data demonstrate that RC-RNase induces cell death on ER-positive but not on ER-negative breast tumors. This study also shows that down-regulation of ER and Bcl-2 is found on RC-RNase-treated ER-positive breast tumors. Additionally, Bcl-2 ovexpression can prevent ER-positive breast tumors from cell death treated with RC-RNase. In summary, this study demonstrates that RC-RNase-induced cell death of ER-positive breast tumors is through regulation of ER and Bcl-2.[[abstract]]RC-RNase exerts anti-cancer effects on many tumors. However, the mechanisms by which RC-RNase induces cytotoxicity in different tumor cells are unclear. Currently, estrogen receptor (ER)-positive and negative breast tumors are treated with RC-RNase. Our data demonstrate that RC-RNase induces cell death on ER-positive but not on ER-negative breast tumors. This study also shows that down-regulation of ER and Bcl-2 is found on RC-RNase-treated ER-positive breast tumors. Additionally, Bcl-2 overxpression can prevent ER-positive breast tumors from cell death treated with RC-RNase. In summary, this study demonstrates that RC-RNase-induced cell death of ER-positive breast tumors is through regulation of ER and Bcl-2

Synergistic anti-tumor activity of isochaihulactone and paclitaxel on human lung cancer cells

[[abstract]]Drug resistance frequently develops in tumors during chemotherapy. Therefore, to improve the clinical outcome, more effective and tolerable combination treatment strategies are needed. Here, we show that isochaihulactone (K8) enhanced paclitaxel-induced apoptotic death in human lung cancer cells, and the enhancing effect was related to increased NSAID-activated gene-1 (NAG-1) expression. CalcuSyn software was used to evaluate the synergistic interaction of K8 and paclitaxel on human lung cancer cells; the synergistic effect of K8 in combination with paclitaxel was increased more than either of these drugs alone. Furthermore, the activity of ERK1/2 was enhanced by the combination of K8 and paclitaxel, and an ERK1/2 inhibitor dramatically inhibited NAG-1 expression in human lung cancer cells. Therefore, this synergistic apoptotic effect in human lung cancer cells may be directly associated with K8-induced NAG-1 expression through ERK1/2 activation. Moreover, over-expression of NAG-1 enhanced K8/paclitaxel-induced apoptosis in human lung cancer cells. In addition, treatment of nude mice with K8 combined with paclitaxel induced phospho-ERK1/2 and NAG-1 expression in vivo. Targeting of NAG-1 signaling could enhance therapeutic efficacy in lung cancer. Our results reveal that activation of NAG-1 by K8 enhanced the therapeutic efficacy of paclitaxel in human lung cancer cells via the ERK1/2 signaling pathway