End-stage chronic renal failure in patients treated by antireflux operation

全例逆流性腎症によると考えられる蛋白尿を術前から有していた.1例ではPaquin法, 2例ではPolitano-Leadbetter法が施行されていた.腎機能の急速な悪化は, 全例で思春期以降で, 2症例では初診時すでにsmall kidneyが認められていたWe report 3 patients progressed to end-stage chronic renal failure after antireflux surgery. Preoperatively, the 3 patients had proteinuria, probably due to reflux nephropathy. Surgical procedures used were Paquin's method in 1 patient and Politano-Leadbetter's method in 2. Rapid deterioration of renal function was observed from puberty in all patients. In addition, renal hypoplasia was suspected in 2 patients. We concluded that both reflux nephropathy and renal hypoplasia played important roles in the progression of renal insufficiency

双目视觉绳系支撑飞行器模型位姿动态测量

绳牵引并联机器人(WDPR)为风洞试验提供了一种新型支撑方式,可用于多/六自由度风洞复杂动态试验。针对该支撑下飞行器模型的大范围运动,发展了一种基于双目视觉的模型位姿动态测量方法。首先,设计了一种编码合作标志点,合理布置于模型表面,通过图像处理消除绳对标志点成像干扰,进行标志点三维重构;然后,利用绝对定姿算法求解相对位姿初值,且给出了理论误差分析,并基于双目相机重投影误差构建李代数下的无约束最小二乘优化问题,采用L-M算法进行位姿优化;最后,采用该测量系统分别进行了静态和动态精度验证试验,以及大迎角俯仰振荡等3种单/多自由度典型运动轨迹测量。试验数据显示,静态角度和位移测量精度分别优于0.02°/0.02mm;动态测量时角度精度可达到0.1°量级,位移平均误差为0.4mm。研究结果表明:设计的双目视觉测量系统是有效可行的,可为后续风洞试验的实际应用提供支持。国家自然科学基金(11702232,11472234)中央高校基本科研业务费专项资金(20720180071)~

双目视觉绳系支撑飞行器模型位姿动态测量

基于机器人技术的绳牵引并联机构为风洞试验提供了一种新型支撑方式,可用于多/六自由度风洞复杂动态试验。针对该支撑下飞行器模型的大范围运动,发展了一种基于双目视觉的模型位姿动态测量方法。首先,设计了一种编码合作标志点,合理布置于模型表面,通过图像处理消除绳对标志点成像干扰,进行标志点三维重构;然后,利用绝对定姿算法求解相对位姿初值,且给出了理论误差分析,并基于双目相机重投影误差构建李代数下的无约束最小二乘优化问题,采用L-M算法进行位姿优化。最后,采用该测量系统分别进行了静态和动态精度验证实验,以及大迎角俯仰振荡等三种单/多自由度典型运动轨迹测量。实验数据显示,静态角度和位移测量精度分别优于0.02°/0.02mm;动态测量时角度精度可达到0.1°量级,位移平均误差为0.4mm。上述研究结果表明设计的双目视觉测量系统是有效可行的,可为后续风洞试验的实际应用奠定基础。国家自然科学基金(11702232,11472234);;\n中央高校基本科研业务费(20720180071

微波消融对小鼠肝癌细胞活性和HSP70表达的影响

[目的]探讨微波消融对小鼠肝癌细胞活性和HSP70表达的影响.[方法]建立C57BL/6J小鼠Hepa 1-6肝癌皮下移植模型,采用微波能量以不同的温度消融肝癌,分别用酶组织化学和Western blot检测被消融肝癌组织细胞琥珀酸脱氢酶（SDH）的活性和HSP70的表达,并观察消融后30 d肝癌局部残留率.[结果]经40℃、45℃或50℃,120 s的条件微波消融后,50℃组消融后24 h小鼠肝癌组织细胞的琥珀酸脱氢酶活性明显低于假消融组;该组消融后30 d肝癌局部残留率明显低于假消融组（均P＜0.01）.3个消融组消融后12 h和24 h肝癌组织HSP70的表达均明显高于相应的假消融组（均P＜0.01）,且随消融温度升高表达明显增强.[结论]微波消融可促进小鼠肝癌HSP70的表达,同时在一定消融条件下能明显降低肝癌细胞的活性

Precise Measurement of Cosmic-Ray Proton and Helium Spectra with the BESS Spectrometer

We report cosmic-ray proton and helium spectra in energy ranges of 1 to 120 GeV and 1 to 54 GeV/nucleon, respectively, measured by a balloon flight of the BESS spectrometer in 1998. The magnetic-rigidity of the cosmic-rays was reliably determined by highly precise measurement of the circular track in a uniform solenoidal magnetic field of 1 Tesla. Those spectra were determined within overall uncertainties of +-5 % for protons and +- 10 % for helium nuclei including statistical and systematic errors.Comment: 12 pages, 4 figure

Measurements of Cosmic-ray Low-energy Antiproton and Proton Spectra in a Transient Period of the Solar Field Reversal

The energy spectra of cosmic-ray low-energy antiprotons and protons have been measured by BESS in 1999 and 2000, during a period covering the solar magnetic field reversal. Based on these measurements, a sudden increase of the antiproton to proton flux ratio following the solar magnetic field reversal was observed, and it generally agrees with a drift model of the solar modulation.Comment: 4 pages, 4 figures, revised version accepted for publication in Phys. Rev. Let