753 research outputs found

    Identification of RNA molecules required for pole cell formation in Drosophila embryos

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    It has been believed that popular plasm or localized and specialized cytoplasm in the posterior polar region includes factors required for germ line establishment during early embryogenesis. ...Thesis--University of Tsukuba, D.Sc.(B), no. 585, 1990.3.2

    Nutrient-Dependent Endocycling in Steroidogenic Tissue Dictates Timing of Metamorphosis in Drosophila melanogaster

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    Many animals have an intrinsic growth checkpoint during juvenile development, after which an irreversible decision is made to upregulate steroidogenesis, triggering the metamorphic juvenile-to-adult transition. However, a molecular process underlying such a critical developmental decision remains obscure. Here we show that nutrient-dependent endocycling in steroidogenic cells provides the machinery necessary for irreversible activation of metamorphosis in Drosophila melanogaster. Endocycle progression in cells of the prothoracic gland (PG) is tightly coupled with the growth checkpoint, and block of endocycle in PG cells causes larval developmental arrest due to reduction in biosynthesis of the steroid hormone ecdysone. Moreover, inhibition of the nutrient sensor target of rapamycin (TOR) in the PG during the checkpoint period causes endocycle inhibition and developmental arrest, which can be rescued by inducing additional rounds of endocycles by Cyclin E. We propose that a TOR-mediated cell cycle checkpoint in steroidogenic tissue provides a systemic growth checkpoint for reproductive maturation

    Norm-based Analysis of Transformers

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    Tohoku University博士(情報科学)thesi

    A Ring-structured Retrieval System for Moss Specimens

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    第2回極域科学シンポジウム/第33回極域生物シンポジウム 11月18日(金) 統計数理研究所 3階リフレッシュフロ

    Genetic network regulating PGC formation in Drosophila

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    科学研究費助成事業 研究成果報告書:新学術領域研究(研究領域提案型)2013-2017課題番号 : 25114002research repor
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