753 research outputs found
Identification of RNA molecules required for pole cell formation in Drosophila embryos
It has been believed that popular plasm or localized and specialized cytoplasm in the posterior polar region includes factors required for germ line establishment during early embryogenesis. ...Thesis--University of Tsukuba, D.Sc.(B), no. 585, 1990.3.2
Nutrient-Dependent Endocycling in Steroidogenic Tissue Dictates Timing of Metamorphosis in Drosophila melanogaster
Many animals have an intrinsic growth checkpoint during juvenile development, after which an irreversible decision is made to upregulate steroidogenesis, triggering the metamorphic juvenile-to-adult transition. However, a molecular process underlying such a critical developmental decision remains obscure. Here we show that nutrient-dependent endocycling in steroidogenic cells provides the machinery necessary for irreversible activation of metamorphosis in Drosophila melanogaster. Endocycle progression in cells of the prothoracic gland (PG) is tightly coupled with the growth checkpoint, and block of endocycle in PG cells causes larval developmental arrest due to reduction in biosynthesis of the steroid hormone ecdysone. Moreover, inhibition of the nutrient sensor target of rapamycin (TOR) in the PG during the checkpoint period causes endocycle inhibition and developmental arrest, which can be rescued by inducing additional rounds of endocycles by Cyclin E. We propose that a TOR-mediated cell cycle checkpoint in steroidogenic tissue provides a systemic growth checkpoint for reproductive maturation
A Ring-structured Retrieval System for Moss Specimens
第2回極域科学シンポジウム/第33回極域生物シンポジウム 11月18日(金) 統計数理研究所 3階リフレッシュフロ
Short-term effects of the chemical components of fine particulate matter on pulmonary function:A repeated panel study among adolescents
兵庫医科大学博士(医学)2023年度doctoral thesi
Genetic network regulating PGC formation in Drosophila
科学研究費助成事業 研究成果報告書:新学術領域研究(研究領域提案型)2013-2017課題番号 : 25114002research repor
Association of Femoral Rotation with Whole Body Alignment in Patients Who Underwent Total Hip Arthroplasty
横浜市立大学2020年
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