小潮气量机械通气期间肺开放策略对肺损伤标志物的影响

【目的】探索外科手术中小潮气量机械通气期间应用间断肺复张手法（RM）联合中等水平呼气末正压（PEEP）构成的肺开放策略（OLS）对血浆中肺损伤标志物晚期糖基化终产物可溶性受体（sRAGE）及Clara细胞蛋白（CC16）浓度的影响。【方法】本研究纳入行择期腹腔镜结直肠癌切除术的患者100例，随机（1∶1）分为开放策略组（OLS）和非开放策略（NOLS）组。两组均使用小潮气量机械通气；OLS组机械通气期间间断给予RM并设置PEEP为6~8cmH2O，NOLS组不予RM及PEEP。麻醉诱导前（T1）、术毕后即刻（T2）及术后第3天（T3）分别取血检测血浆sRAGE、CC16浓度。【结果】在T1、T2、T33个时间点，血浆sRAGE、CC16浓度组间均无统计学差异（>0.05）。所有患者中，T2、T3sRAGE浓度高于T1，T3sRAGE浓度高于T2，T3CC16浓度高于T1、T2，均有统计学差异（<0.05）。【结论】术中小潮气量机械通气期间，应用间断RM联合中等水平PEEP的肺开放策略不能改变术后三天内血浆肺损伤标志物sRAGE和CC16的水平

Copper and Nickel Removal from Electroplating Wastewater Using Two-Step Coagulation Method

利用两步混凝法对某电镀废水中的Cu2+和nI 2+进行去除,并对混凝剂的类型、混凝剂和助凝剂投加量、废水PH等工艺参数进行了优化,该方法可作为该电镀废水的处理方法.结果显示,当溶液PH值为11.0、混凝剂聚合氯化铝铁的投加量为1.0g/l、助凝剂聚丙烯酰胺投加量为0.2g/l时,电镀废水具有最好的处理效果,处理后废水中Cu2+和nI 2+的质量浓度分别为0.13Mg/l和0.06Mg/l.同时,处理成本可降至1.9元/M3.A two-step coagulation method is used to remove Cu2+and Ni 2+from an electroplating wastewater.The experimental parameters including coagulant type,dosage of coagulant and coagulant aids,wastewater pH are optimized.The results show that when wastewater pH value,dosage of coagulant polyaluminum ferric chloride and dosage of coagulant aids polyacrylamide are 11.0,1.0g/L and 0.2g/L respectively,the electroplating wastewater has the best removal efficiency.Under the optimization experimental conditions,the Cu2+and Ni 2+concentrations are 0.13mg/L and 0.06mg/L respectively.Meanwhile,the treatment cost can be reduced to 1.9RMB/m3;therefore,the method is a feasible technique for treating the electroplating wastewater.国家自然科学基金面上项目(21077086);国家自然科学基金青年基金项目(51209123); 湖北省教育厅项目(B2013174

Prediction of Energy Resolution in the JUNO Experiment

International audienceThis paper presents the energy resolution study in the JUNO experiment, incorporating the latest knowledge acquired during the detector construction phase. The determination of neutrino mass ordering in JUNO requires an exceptional energy resolution better than 3% at 1 MeV. To achieve this ambitious goal, significant efforts have been undertaken in the design and production of the key components of the JUNO detector. Various factors affecting the detection of inverse beta decay signals have an impact on the energy resolution, extending beyond the statistical fluctuations of the detected number of photons, such as the properties of liquid scintillator, performance of photomultiplier tubes, and the energy reconstruction algorithm. To account for these effects, a full JUNO simulation and reconstruction approach is employed. This enables the modeling of all relevant effects and the evaluation of associated inputs to accurately estimate the energy resolution. The study reveals an energy resolution of 2.95% at 1 MeV. Furthermore, the study assesses the contribution of major effects to the overall energy resolution budget. This analysis serves as a reference for interpreting future measurements of energy resolution during JUNO data taking. Moreover, it provides a guideline in comprehending the energy resolution characteristics of liquid scintillator-based detectors

JUNO Sensitivity on Proton Decay p→νˉK+p\to \bar\nu K^+ Searches

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in $p\to \bar\nu K^+$ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar\nu K^+$ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is $9.6 \times 10^{33}$ years, competitive with the current best limits on the proton lifetime in this channel

JUNO sensitivity on proton decay p → ν K + searches*

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this study, the potential of searching for proton decay in the $p\to \bar{\nu} K^+$ mode with JUNO is investigated. The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar{\nu} K^+$ is 36.9% ± 4.9% with a background level of $0.2\pm 0.05({\rm syst})\pm$$0.2({\rm stat})$ events after 10 years of data collection. The estimated sensitivity based on 200 kton-years of exposure is $9.6 \times 10^{33}$ years, which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies