Research on Energy-saving Potential and CO2 Emission of Chinese Nonferrous Metals Industry

目前我国面临一定的能源困境：一方面我国仍处于工业化和城镇化高速发展期，经济需保持发展，能源需求的刚性将带来能源消费总量的继续增长，那么能源供给规模还需继续扩大、供给能力还需进一步增强；另一方面，国内能源供给日益趋紧，石油、天然气等能源对外依存度不断上升，以煤炭为主的能源消费结构对环境的压力与日俱增，减少二氧化碳排放的国际压力越来越大。在此背景下，政府开始制定能源消费总量控制方案，虽然最终版本的《控制能源消费总量工作方案》尚未出台，但国家发改委提出了预期目标：“十二五”期末我国能源消费总量目标控制在40亿吨标准煤左右，用电量控制在6.15万亿千瓦时。有色金属工业是典型的高耗能产业，其能源消费量、...China is in the rapid progress of industrialization and urbanization, which means there are contradictions between economic growth and energy supply and environmental pollution. On the one hand it will be a strong requirement of energy. On the other hand, the strategy of “controlling total amount of energy demand of the country” and the gradual execution of carbon intensity index in 2020, energy s...学位：经济学博士院系专业：经济学院_能源经济学学号：3132010015378

A Study on Production Function of R&D in Universities of China

在当今科学技术高度发达的知识经济时代，国家经济的发展越来越依靠科学技术的进步。高等教育作为一国重要的科技开发产业其发展势必极大的影响一个国家的经济前景和国际竞争力。因此越来越多的国家不遗余力的投资高校的科研活动，高校的科研活动也成为不少学者十分关心的问题。 本文将研究高等学校的科技投入产出关系，通过构建高校的科技生产函数并进行实证分析，我们希望可以让高校的管理者对高校的科研生产活动有更深刻的理解，从而可以更合理的配置科研资源，最终达到提高我国高校科研活动生产效率的目的，此外还希望我们的研究能让大家对我国高校地域不均衡问题有不同角度的认识。 文章首先对我国高校2007-2012年间的科研投入...In the knowledge-based economy epoch, the competitiveness of comprehensive national strength is based on the strength of a nation’s science. The R&D of universities is an essential part in every nation’s system of R&D, which will influence the development of a country's economic and the international competitiveness, so more and more countries spare no effort to invest in the R&D of universities. ...学位：经济学硕士院系专业：经济学院_财政学(含税收学)学号：1552011115181

西部人才开发面临的主要问题与对策

人才是西部大开发的关键。本文对西部人才开发的制约因素及西部地区人力资源现状问题进行了较为详细的论述 ,进而提出了西部人才开发战略的具体对策 ,主要是 :增强人才观念 ,实施人力资本优先积累战略 ,发展教育 ,加强干部素质 ,营建科学的人才机制 ,培养、引进专业人才 ,注重创新

增加土地供给能否有效抑制房价上涨——利用“撤县设区”的准实验研究

为抑制重点城市房价的过快上涨,近年来我国政府出台了很多调控政策。其中,供给侧的土地调控是近期以来的重点。虽然关于土地供给与房价的关系已有很多学者关注,但由于两者之间存在很强的内生性,导致得到的结论不一,甚至出现完全相反的情况。基于此,本文首先通过建立一个静态局部均衡模型,说明政府的土地供给行为对房价的影响机制;其次创新性地利用\"撤县设区\"这一准自然实验,并基于2000—2013年中国267个地级市的面板数据,运用PSM-DID方法研究了土地供给对城市房价的影响,很好地规避了两者的内生性问题。研究表明,土地供给规模的扩大的确有助于降低城市的房价水平。这一结论在排除城镇化推动商品房市场需求增长的情况后依然成立。因此,扩大土地供给规模以缓解供需矛盾是调控我国中心城市房价的有效手段。国家自然基金面上项目“交通设施的空间网络特征及异质性产业集聚效应研究”(71573218

双链探针同步荧光技术快速筛查C282Y点突变

以荧光染料Fam和Joe分别标记野生型和突变型双链探针作为均相检测探针,以构建的DNA模板作为研究模型,采用固定波长差同步荧光分析法对PCR反应产物进行终点检测。通过对HFE基因C282Y点突变的检测,并以限制性内切核酸酶RsaI证实,该方法是一种廉价、快速、可靠的筛查遗传性血色病基因C282Y突变的方法,该法可扩展到各种基因的突变检测

Identification of Colorants in Food by Surface-enhanced Raman Spectroscopy and Wavelet-based Reverse Search

使用金纳米粒子为增强因子的表面增强拉曼光谱技术,通过连续小波变换将拉曼光谱信号转化到小波空间(墨西哥帽小波作为小波基)。该步骤能够减轻信号中基线; 变化及随机噪音的影响并找到峰位置和最佳小波尺度系数。依据小波空间中的信息,对混合物光谱及标准谱光谱进行反向搜索得到反向搜索匹配系数(Revere; match quality,; RMQ),作为判断混合物中目标成分是否存在的依据。该算法可对混合物中的目标物质进行准确定性,并已成功应用于多种食品中色素鉴定。食品中色素的检出率; 达到99%,且结果稳健,其效果明显优于传统的命中质量系数法(Hit quality index,; HQI)。这证实了小波空间反向搜索方法是一种快速而准确的拉曼光谱定性算法。In this study, a gold nanocrystal colloid was used as the enhancement; factor for surfaceenhanced Raman scattering (SERS). Raman spectra were; transformed by continuous wavelet transform (CWT),and Mexican hat; wavelet were chosen as the wavelet basis. This procedure could be used; to alleviate the influence of baseline variations and random noise,and; find peak positions and the best scale wavelet coefficients of signal.; Reverse search method was proposed to compare the spectrum of an unknown; sample with a spectrum of standard using the information in wavelet; space. Reverse match quality (RMQ) could be obtained automatically to; determine whether a substance is present. It was used to identify; colorants in a variety of food successfully. The colorants could be; identified with 99 percent accuracy. It shows a better performance; compared with traditional hit quality index (HQI). The study confirmed; that the wavelet-based reverse search is feasible and accurate in; qualitative analysis.国家自然科学基金资助项目; 国家重大科学仪器设备开发专

Clinical Research of Kangshi Kangxian Recipe Treating on Hepatic Fibrosis of Chronic Hepatitis B

目的观察康氏抗纤方治疗慢性乙型肝炎肝纤维化的临床疗效,探讨其对肝组织N-花生四烯酸氨基乙醇(; arachidonoylethanolamine,AEA) 、2-花生四烯酸甘油( 2-arachidonoylglycerol,2-AG); 、大麻素受体1( cannabinoid receptor 1,CBR1) mRNA、大麻素受体2( cannabinoid receptor; 1,CBR2); mRNA含量变化的影响。方法将110例慢性乙型肝炎肝纤维化患者按随机数字表法分为治疗组和对照组,每组55例。治疗组予中药康氏抗纤方联合恩替卡韦分; 散片治疗,对照组用恩替卡韦分散片单药治疗,两组均治疗48周。判定两组临床疗效,检测血清ALT水平,HBV; DNA、HBsAg、HBsAb定量,肝组织病理、肝硬度变化,肝组织AEA、 2-AG含量和CBR1、CBR2; mRNA表达水平。结果与对照组比较,治疗组的临床总有效率、HBsAg阴转率、肝组织纤维化分期疗效有效率均高于对照组(chi~2 =; 4.453,4.152,6.364,均P < 0.05); 。与本组治疗前比较,治疗后两组患者肝纤维化瞬时弹性测定值、AEA、2-AG含量及CBR1、CBR2 mRNA表达均降低(均P <; 0.05),且治疗组降低更明显(均P < 0.05); 。肝组织病理显示:治疗后治疗组肝小叶结构基本完整,肝细胞轻度水样变性,汇管区纤维组织无增生,局部少量淋巴细胞浸润,炎症及纤维化较对照组明显改善。; 结论康氏抗纤方具有提高慢性乙型肝炎肝纤维化患者的临床总有效率、HBsAg阴转率、肝组织纤维化分期疗效有效率,其作用机制可能与调节内源性大麻素系统; 有关。Objective To observe the clinical effect of Kangshi Kangxian Decoction (; KSKXD) in treating on patients of hepatic fibrosis of chronic hepatitis; B ( CHB),and to explore the mechanisms of KSKXD by regulating the; contents of arachidonoylethanolamine ( AEA),2-arachidonoylglycerol (; 2-AG),cannabinoid receptor 1 ( CBR1 mRNA) and cannabinoid receptor 2 (; CBR2 mRNA) in the liver tissue. Methods Totally 110 patients with; hepatic fibrosis of CHB were assigned to the treatment group and the; control group according to random digit table,55 cases in each group.; The treatment group was treated with Chinese herb KSKXD combined with; Entecavir,and the control group was treated with Entecavir. Both of the; two groups were treated for 48 weeks. The clinical efficacy of the two; groups was determined. The serum ALT levels,HBV DNA, HBsAg and HBsAb; quantification,liver pathological changes,liver stiffness; changes,contents of AEA and 2-AG,mRNA expression of CBR1 and CBR2 in the; liver tissue were detected. Results The total effective rate,HBsAg; negative conversion rate,hepatic fibrosis staging and curative effect; rate of the treatment group were higher than those of the control group; (chi~2 = 4.453,4.152,6.364,allP <0.05). After treatment,the; instantaneous elasticity of liver fibrosis,the contents of AEA and; 2-AG,the mRNA expressions of CBR1 and CBR2 in the liver tissue in the; two groups were decreased compared to those of the same group before; treatment (P < 0.05),and the treatment group had better effect than that; of the control group (P < 0.05). The pathological changes in the; treatment group after treatment indicated the liver lobules; integrity,mild hydropic degeneration of liver cells,periportal fibrous; tissue hyperplasia,local small lymphocytic infiltration,which fibrosis; and inflammation were better than those of the control group.; Conclusions KSKXD was effective in the treatment of hepatic fibrosis of; CHB, which improved total effective rate,HBsAg seroconversion rate and; liver fibrosis stage efficiency. And its mechanism maybe related to the; regulation of the endocannabinoid system.国家自然科学基金资助项目; 福建省科技计划引导性项目; 厦门市科技惠民项目; 福建中医药大学临床专项校管课题基

Essence of tongue diagnosis of HE Meng-yao

岭南,指中国五岭以南的地区,相当于现在广东、广西及海南全境。因气候炎热潮湿,人群多脾胃虚弱,病多阳虚、痰湿。从晋代以后,当地医家以中原医学为基础; ,结合岭南特殊气候和人群体质特点,逐渐形成独具风格的岭南医学流派。何梦瑶作为岭南名医之一,其医术高明,医学著作颇丰,极大地促进了岭南医学的发展。; 《医碥》是其代表作之一,亦是其学术思想的精髓,为现代研究何梦瑶学术思想和岭南医家流派的主要古籍。其中所记载的舌诊方法,至今仍具有临床实用意义。Lingnan, Chinese refers to the south of the five ridges area, which is; equivalent to the current Guangdong province, Guangxi province and; Hainan province. All due to the hot and humid climate, majority of local; people are with spleen and stomach deficiency, most of the clinical; manifestation are yang deficiency and dampness. After the Jin dynasty,; based on the traditional Chinese medicine of central plains, the local; doctors gradually formed their unique medical schools, combining with; the characteristics of the local climate and peoples constitutions. As; one of the famous specialists in the south of the five ridges, HE; Meng-yao, greatly promote the development of local medical health level.; Yibian is one of his famous masterpieces, which is also the essence of; the his medicine. Records of tongue diagnosis in this book are still; practical in clinical.国家自然科学基金资助项目; 福建中医药大学校管课题; 福建省科技计划引导性项

Efficacy of Zaozhu Yinchen Recipe for Treating Non-alcoholic Steatohepatitis and Its Effect on Free Fatty Acid and TNF-α

目的观察皂术茵陈方治疗非酒精性脂肪性肝炎(non-alcoholic steatohepatitis,NASH)患者的临床疗效,并探讨其对游离脂肪酸(free fatty acid,FFA)及TNF-α的影响。方法采用随机数字表法将120例NASH患者分为治疗组及对照组,每组60例。治疗组予中药皂术茵陈方,每日1剂;对照组予水飞蓟宾葡甲胺片200 mg口服,每日3次,两组均治疗24周。分别于治疗前后通过检测血清ALT、AST活性及TC、TG水平;行腹部CT计算肝脾CT比值;应用肝组织病理检查评价非酒精性脂肪性肝病活动度积分(NAFLD activity score,NAS)及纤维化程度以评价临床疗效;并检测血清FFA及TNF-α含量。结果与本组治疗前比较,两组治疗后血清ALT、AST、TC、TG、FFA、TNF-α水平、肝组织NAS积分及症状体征积分均明显降低,肝纤维化程度明显改善(P<0.05,P<0.01),且治疗组降低更明显(P<0.05)。治疗24周后,治疗组肝纤维化分期总有效率及临床总有效率分别为80.00%(48/60)、85.00%(51/60),明显高于对照组[60.00%(36/60)、73.33%(44/60)],两组比较,差异有统计学意义(P<0.05,P<0.01)。结论皂术茵陈方可改善NASH患者的临床疗效,其作用可能与抑制血清FFA及TNF-α水平有关。Objective To observe the efficacy of Zaozhu Yinchen Recipe(ZZYCR) on non-alcoholic steatohepatitis(NASH) patients, and to explore its effect on serum free fatty acid(FFA) and tumor necrosis factor α(TNF-α).Methods Totally 120 patients with NASH were randomly assigned to the treatment group(60 cases,treated with ZZYCR, one dose per day) and the control group(60 cases, treated with Silibin Meglumine Tablets, 20 mg each time, thrice per day). The therapeutic course for all was 24 weeks. Serum levels of ALT and AST activities, TC and TG levels were detected before and after treatment. Peritoneal CT was performed in all patients, and CT ratios of liver and spleen calculated. NAFLD activity score(NAS) and degree of hepatic fibrosis were assessed using pathological examinations of liver tissue, and efficacy also evaluated. Serum contents of FFA and TNF-αwere also detected. Results Compared with before treatment in the same group, activities of ALT and AST, serum levels of TC, TG, FFA, and TNF-α, NAS, scores of symptoms and signs all obviously decreased, degree of hepatic fibrosis was obviously improved in the two groups(P < 0. 05, P < 0. 01). These changes were more obviously seen in the treatment group(P < 0. 05). After 24-week treatment, the total effective rate and total clinical efficacy were 80. 00%(48/60 cases) and 85. 00%(51/60 cases) in the treatment group, obviously higher than those in the control group [60. 00%(36/60 cases) and 73. 33%(44/60 cases) respectively], with significant difference(P < 0. 05, P < 0. 01). Conclusion ZZYCR could improve the clinical efficacy of NASH patients, and its mechanism might be associated with inhibiting serum levels of FFA and TNF-α.国家自然科学基金资助项目(No.81503529,81274155);; 福建省自然科学基金面上资助项目(No.2014J01374);; 福建省卫生厅中医药项目(No.wzpw201308);; 厦门市科技计划项目(No.3502Z20134020