Study on the Informationization Construction of Guiyang XX Automobile Trade Group

本文从贵阳某汽贸集团信息系统实际使用情况出发，整理、总结了现阶段汽贸集团运营管理方面日益显现的问题，尽管企业在信息化建设方面不断增加投入，信息系统不断增加，但仍然难以有效的满足业务部门对应用系统的需要。信息化系统的建设是一个风险性大，资金投入量高的系统工程，许多的企业为了建设信息化项目，不牺投入了企业大量的人力、物力、财力，然而，由于种种原因，建设的信息化项目都不是自己预期的目标或最终企业期望的效果，或者在项目建设的中期，项目不得不停顿、瘫痪，最后以失败告终。其本质原因主要是由于信息化项目管理不全面，缺乏科学有效的项目管理方法和风险控制是失败的一个重要因素。 文章重点阐述面对以上问题，针对贵...From the Guiyang automobile trade group information system in the actual use of the situation,, this article has sorted and summarized problems gradually appearing on operations management of auto trade group at the present stage. Although the investment and information system of enterprise information construction are on the increase, they cannot satisfy the requirement of operating department fo...学位：工商管理硕士院系专业：管理学院_工商管理硕士(高级管理人员工商管理硕士)学号：X201015635

阿托伐他汀对心室重塑和心肌 AVP、TGF-β1的影响

【目的】探讨阿托伐他汀能否通过抑制AVP的分泌而延缓心肌纤维化，为改善心肌梗死后心室重塑提供新思路。【方法】通过结扎大鼠冠状动脉前降支建立大鼠心肌梗死模型。建模成功后将大鼠分为假手术组（sham组）、心肌梗死大鼠安慰剂治疗组（MI组）及心肌梗死大鼠阿托伐他汀治疗组（A组），每组各有10只大鼠。干预5周后，超声心动图检测大鼠心功能；处死大鼠后，收集心肌组织标本，计算左心室质量指数；ELISA法检测左心室非梗死区和血清的血管加压素（AVP）含量；Masson染色检测心肌间质纤维化水平；免疫组织化学染色检测左心室非梗死区Ⅰ型胶原的表达；Western blot测定左心室非梗死区转化生长因子-β1（TGF-β1）蛋白的表达。【结果】干预5周后，Sham组、MI组和A组分别存活10只、9只和10只大鼠。与Sham组大鼠比较，MI组和A组大鼠的左室质量（LVM）和左室质量指数（LVMI）增加、左室射血分数（LVEF）降低、心肌间质纤维化明显加重、左心室非梗死区Ⅰ型胶原蛋白的表达、AVP含量以及TGF-β1蛋白表达水平明显升高（P<0.05）；阿托伐他汀干预后，LVM和LVMI降低、LVEF升高、心肌间质纤维化减轻、左心室非梗死区Ⅰ型胶原蛋白的表达、AVP的含量以及TGF-β1的蛋白表达水平显著降低（P<0.05）。【结论】阿托伐他汀能够改善心肌梗死后心室重塑，可能与抑制心室AVP的分泌及下调TGF-β1的表达有关

一种核壳型金/介孔硅碳复合纳米材料、制备方法及应用

一种核壳型金/介孔硅碳复合纳米材料、制备方法及应用，本发明的特点是合成以金纳米粒子为内核、具有有序介孔结构二氧化硅-表面活性剂为外壳的核壳型纳米材料，通过表面活性剂在介孔二氧化硅外壳中的原位碳化，制备金纳米粒子为内核、介孔硅碳复合结构为外壳的核壳型纳米材料。该材料具有高比表面积、高孔容、均一有序介孔结构硅碳外壳包覆且壳层厚度可控的特性。此纳米材料主要作为表面辅助激光解吸离子化质谱的基质，可避免传统有机基质在低分子量范围的背景干扰，实现待测化合物的高效激光解吸离子化

pH响应的包覆超顺磁性纳米颗粒的γ-聚谷氨酸二级结构研究

用傅里叶红外光谱法（FTIR）定量研究了pH对包覆超顺磁性纳米颗粒的γ-聚谷氨酸（γ-PGA）二级结构变化的影响。结合傅里叶去卷积技术和二阶导数法对原始谱带（酰胺I带）进行高斯拟合，计算了二级结构的相对百分含量。红外结果显示：pH变化影响γ-PGA的二级结构。γ-聚谷氨酸磁性纳米微球中γ-PGA的β折叠和β转角的总含量很大，达65％以上，而旷螺旋和无规卷曲的含量则比较少。随着pH值的增大，β折叠的含量逐渐减少相反β转角的含量逐渐增大。γ-PGA二级结构变化与γ-聚谷氨酸磁性纳米微球在水溶液的稳定性有关。考察了γ-聚谷氨酸纳米微球的zeta电位随pH的变化。结果表明，pH为10．2时zeta电位出现极小值，其绝对值最大，颗粒稳定性最好

effectsofpaddlestypesonthepreparationofultrafinegoethiteparticles

Typical stirring paddles inducing radical flow and axial flow as well as axial and radical flow were selected in order to investigate their effects on the process of goethite preparation. Experimental results show that PBT (pitched blade turbine) inducing axial and radical flow reveals good dispersibility and complete mixing properties, and makes apparent reaction rate of the system larger. Moreover, with the increase of reaction time, the viscosity value of reaction system becomes large at first, and then amounts to a plateau, increases again at last. At the same time, ultrafine goethite particles prepared by PBT are with narrow particles' size distribution, uniform morphology and few dendrities

Effects of paddle's types on the preparation of ultrafine goethite particles

Typical stirring paddles inducing radical flow and axial flow as well as axial and radical flow were selected in order to investigate their effects on the process of goethite preparation. Experimental results show that PBT (pitched blade turbine) inducing axial and radical flow reveals good dispersibility and complete mixing properties, and makes apparent reaction rate of the system larger. Moreover, with the increase of reaction time, the viscosity value of reaction system becomes large at first, and then amounts to a plateau, increases again at last. At the same time, ultrafine goethite particles prepared by PBT are with narrow particles' size distribution, uniform morphology and few dendrities