Progress of C_2-Symmetric Biphenyl Bisphosphine Ligands Ⅲ

手性膦配体的合成及其在手性诱导催化反应中的应用一直是不对称合成与催化研究中非常重要的研究领域之一。近10年来,大量的C2-轴对称手性双膦配体被合成出来并成功地应用于不对称催化研究,本文从C2-轴对称联苯类手性双膦配体的介绍、合成方法、C2-轴对称联苯类手性双膦配体在不对称催化氢化、以及其在其他不对称诱导反应中的应用4个方面综述了相关研究进展,并对今后配体的合成及应用前景进行了展望。A vast number of biphenyl atropisomeric diphosphine ligands are successfully applied in asymmetric catalysis.The synthesis and applications of this type of ligands are a continuous interesting theme in organic chemistry.This review describes recent progress in synthesis and application of C2-Symmetric diphosphine ligands on the asymmetric catalysis hydrogenation and other asymmetric induced reaction,and the future ligand synthesis and application prospect.国家自然科学基金(20272037); 教育部博士点基金(20080610022); 四川自然科学基金重点项目(07ZA109

Progress of C_2-Symmetric Biphenyl Bisphosphine LigandsⅡ

手性膦配体的合成及其在手性诱导催化反应中的应用一直是不对称合成与催化研究中非常重要的研究领域之一。近十年来,大量的C2-轴对称手性双膦配体被合成出来并成功地应用于不对称催化研究,本文从C2-轴对称联苯类手性双膦配体的介绍、合成方法、C2-轴对称联苯类手性双膦配体在不对称催化氢化以及其在其他不对称诱导反应中的应用4个方面综述了相关研究进展。A vast number of biphenyl atropisomeric diphosphine ligands have been successfully applied in asymmetric catalysis.The synthesis and applications of this type of ligands are a continuous interesting theme in organic chemistry.This review describes recent progress in synthesis and application of C2-Symmetric diphosphine ligands on the asymmetric catalysis hydrogenation and other asymmetric induced reaction.国家自然科学基金(20272037); 教育部博士点基金(20080610022); 四川自然科学基金重点项目(07ZA109

Progress of the Study on C_2-symmetric Biphenyl Bisphosphine Ligands(一)

手性膦配体的合成及其在手性诱导催化反应中的应用一直是不对称合成与催化研究中非常重要的研究领域之一。近10年来,大量的C2-轴对称手性双膦配体被合成出来并成功地应用于不对称催化研究,本文从C2-轴对称联苯类手性双膦配体的介绍、合成方法,C2-轴对称联苯类手性双膦配体在不对称催化氢化,以及其在其他不对称诱导反应中的应用4个方面综述了相关研究进展,并对今后配体的合成及应用前景进行了展望。A vast number of biphenyl atropisomeric diphosphine ligands are successfully applied in asymmetric catalysis.The synthesis and applications of this type of ligands are a continuous interesting theme in organic chemistry.This review describes recent progress in synthesis and application of C2-Symmetric diphosphine ligands in the asymmetric catalysis hydrogenation and other asymmetric induced reaction.And the future ligand synthesis and application are predicted.国家自然科学基金(20272037); 教育部博士点基金(20080610022); 四川自然科学基金重点项目(07ZA109

慢性HBV感染患者抗原表位特异性CTL与ALT水平无关

[目的]通过定量分析慢性乙型肝炎患者体内乙型肝炎病毒（HBV）特异性的细胞毒性T淋巴细胞,探讨特异性细胞毒性T淋巴细胞水平与血清丙氨酸氨基转移酶水平和病毒复制状态的关系.[方法]从慢性乙型肝炎患者外周血分离外周血单个核细胞（PBMC）,用HLA-A2限制的HBcAg抗原表位肽-五聚体复合体及CD8单克隆抗体染色后,用流式细胞仪检测HBV特异性的细胞毒性T淋巴细胞,同时检测患者的肝功能和定量分析HBV DNA.[结果]32例HLA-A2阳性的慢性乙型肝炎患者外周血均可检测到HBV特异性的细胞毒性T淋巴细胞,五聚体阳性细胞占CD8阳性细胞的比例为1.3%±1.1%,统计分析抗原表位特异性细胞毒性T淋巴细胞频率与丙氨酸氨基转移酶水平相关性不显著（r=0.163,P=0.163）.分组对比发现病毒载量低者（HBV DNA定量＜105拷贝/mL）抗原表位特异性细胞毒性T淋巴细胞水平（1.96%±1.26%）高于病毒载量高者（0.82%±0.52%,P＜0.05）.[结论]慢性乙型肝炎患者外周血中存在抗原表位特异性细胞毒性T淋巴细胞,抗原表位特异性细胞毒性T淋巴细胞可能与控制HBV的复制有关,但主要肝损害并非直接由抗原表位特异性细胞毒性T淋巴细胞引起

A Journey into the City. Migrant Workers' Relation with the Urban Space and Struggle for Existence in Xu Zechen's Early Jingpiao Fiction

In contemporary China, rural-urban migrants constitute a new urban subject with entirely new identity-related issues. This study aims at demonstrating how literature can be a valid field in investigating such evolving subjectivities, through an analysis of Xu Zechen’s early novellas depicting migrants’ vicissitudes in Beijing. Combining a close reading of the texts and a review of the main social problems characterising rural-urban migration in China, this paper focuses on the representation of the identity crisis within the migrant self in Xu’s stories, taking into account the network of meanings employed by the writer to signify the objective and subjective tension between the city and the countryside

探讨无人机倾斜摄影测量的关键技术及应用领域

本文通过介绍无人机倾斜摄影测量系统的组成,阐述无人机倾斜摄影测量的关键技术,并对无人机倾斜摄影测量的应用领域进行探究。结果发现：与一般摄影测量相比,倾斜摄影测量打破了垂直角度拍摄的局限性,可以在多台传感器的作用下完成多角度的拍摄,从而获取更加丰富的影像数据,将待测区域的真实地貌地物反映出来；再加上无人机操作灵活、机体轻等优势,使得无人机倾斜摄影测量技术得到了测绘领域的青睐。</jats:p

“互联网+环保”新思路下的大气模拟及生态保护

本文结合现有案例对互联网+环保模式进行分析,并对大气污染中排放的污染物、污染物来源及模型数值模拟内容展开阐述,希望对大气污染治理有所帮助,改善生态环境。</jats:p

瞬间——用镜头留住长江濒危动物

本书作者经过长达28年的积累，足迹踏遍长江中下游的江河故道，镜头扫遍长江中下游的各个角落，饱受雨雪风霜，忍耐无数寂寞，日复一日、年复一年，积累了数万幅珍贵的长江濒危动物照片。经过反复挑选，优中选优，甚至不得不“忍痛割爱”，遴选出这178张照片，将长江珍稀动物的美定格下来，呈献给读者，留给后人。你也许无法在野外看到这些生灵，你也许在博物馆看到过它们的标本，而本书将会因为它们的自然美使你的视觉受到震撼，将会使你的心灵得到升华

大数据时代下航天企业管理和发展的思考

随着云计算技术的日趋完善，人们逐渐进入了大数据时代。航天企业在大数据时代背景下迎来了新的发展契机，通过对大数据的解读，准确判断人们对于出行的方式和选择，形成科学严谨的企业管理制度，对航天企业在大数据时代下的发展具有重要意义。</jats:p

The adsorption of As(Ⅲ) on a novel granular Fe-Cu-Mn trimetal oxide (GFCM): Behavior and mechanism

A novel sorbent of granular Fe-Cu-Mn trimetal oxide (GFCM) was fabricated by coating method,with chitosan as adhesive. The GFCM presents an incomplete spheric shape with a diameter of 0.7~ 1.0 mm. It can effectively oxidize As(Ⅲ) to As(V) and efficiently adsorb the new formed As(V). Its maximal sorption capacity on As(Ⅲ) is up to 56.5 mg&middot;g~(-1) at pH 7.0,which is superior to most of reported granular sorbents. The GFCB also shows excellent As(Ⅲ) sorption efficiency over a wide range of pH from 5.0 to 9.0,and is less affected by ionic strength. The coexisting anions would restrain the As(Ⅲ) sorption efficiency by the following order: PO~(3-)_4 &gt; SiO_3~(2-) &gt; CO_3~(2-) &gt; Cl~-&gt; SO_4~(2-). The arsenic-loaded sorbent could be effectively regenerated by using NaOH solution and reused again. During the process of As(Ⅲ) removal,Mn oxide in sorbent is mainly responsible for As(Ⅲ) oxidation,while both Fe and Cu oxides are dominant for adsorbing As(Ⅲ) and formed As(V). Moreover,Cu oxide contributes to enhance As(Ⅲ) sorption performance of the GFCM.</p