拉米夫定阻断乙型肝炎病毒宫内传播的临床探讨

【目的】研究拉米夫定对HBsAg 阳性孕妇的乙肝病毒(HBV)宫内阻断作用。【方法】拉米夫定组43 例, 孕28 周 起口服拉米夫定, 每天100 mg 至产后30 d 。对照组52 例, 未予用药。两组孕妇均于孕28 周、分娩前, 其新生儿于生后24 h 内免疫接种前抽静脉血检测HBsAg 、HBeAg 及HBV 的定量。【结果】拉米夫定组孕妇HBV 的DNA 水平显著下降(P < 0.05), 其新生儿宫内感染率(16.3 %)明显低于对照组(32.7 %), P <0.05。两组孕妇及其新生儿未发现有不良反应。【结 论】携带HBV 孕妇产前服用拉米夫定可有效减少HBV 宫内感染发生率

Measurement of integrated luminosity of data collected at 3.773 GeV by BESIII from 2021 to 2024

We present a measurement of the integrated luminosity e+e- of collision data collected by the BESIII detector at the BEPCII collider at a center-of-mass energy of Ecm = 3.773 GeV. The integrated luminosities of the datasets taken from December 2021 to June 2022, from November 2022 to June 2023, and from October 2023 to February 2024 were determined to be 4.995±0.019 fb-1, 8.157±0.031 fb-1, and 4.191±0.016 fb-1, respectively, by analyzing large angle Bhabha scattering events. The uncertainties are dominated by systematic effects, and the statistical uncertainties are negligible. Our results provide essential input for future analyses and precision measurements

Determination of the number of ψ(3686) events taken at BESIII

The number of ψ(3686) events collected by the BESIII detector during the 2021 run period is determined to be (2259.3±11.1)×106 by counting inclusive ψ(3686) hadronic events. The uncertainty is systematic and the statistical uncertainty is negligible. Meanwhile, the numbers of ψ(3686) events collected during the 2009 and 2012 run periods are updated to be (107.7±0.6)×106 and (345.4±2.6)×106, respectively. Both numbers are consistent with the previous measurements within one standard deviation. The total number of ψ(3686) events in the three data samples is (2712.4±14.3)×10^