EFFECTS OF CORTICOSTERONE ON MORPHINE-INDUCED CONDITIONED PLACE PREFERENCE AND CONDITIONED LOCOMOTION ACTIVITY

目的 :研究皮质酮作用下吗啡条件性位置偏爱 (CPP)及条件性精神运动的变化趋势及其可能机制 ,为探讨应激、环境线索诱发复吸的机制提供基础。方法 :32只♂SD大鼠分成 4组。训练 2d ,1次药物匹配训练 (吗啡 2mg·kg- 1 ,皮质酮 5mg·kg- 1 ,ip ,提前 2 0min注射 ) ,1次生理盐水训练。观察训练前后大鼠在伴药侧停留的时间 ,急性给药后的运动及条件性精神运动的变化。结果 :(1)吗啡组训练后在伴药侧停留的时间显著长于对照组 (P 0 0 5 ) ; (2 )在 5 0、6 0min时皮质酮吗啡组的急性精神运动显著大于吗啡组和对照组 (P <0 0 1) ; (3)皮质酮吗啡组大鼠的条件性精神运动显著大于对照组、吗啡组 (P <0 0 1,P <0 0 5 )。结论 :5mg·kg- 1 的皮质酮显著抑制吗啡CPP的获得 ,但促进吗啡条件性精神运动的获得以及急性精神运动。CPP与条件性精神运动获得的机制可能存在差

Mirk/Dyrk1b在上皮性卵巢癌组织中的表达及意义

目的:探讨Mirk/Dryk1b(Minibrain-related kinase/Dual specificity tyrosine-phosphorylation-regulated kinase1B)在卵巢组织中的表达及其临床意义。方法:利用免疫组化检测Mirk/Dyrk1b在30例上皮性卵巢癌、20例上皮性卵巢囊腺瘤、10例正常卵巢组织中的表达。结果:Dyrk1b在上皮性卵巢癌中的表达明显高于上皮性卵巢囊腺瘤及正常卵巢组织(P0.05)。结论:Dyrk1b在上皮性卵巢癌中高表达,提示其可能参与了肿瘤的发生和发展,并有望成为临床早期诊断的肿瘤标志物和新的卵巢癌治疗的靶基因

采用涂有紫外线辐射反应材料的结构进行印刷的方法

本发明涉及采用涂有紫外线辐射反应材料的结构进行印刷的方法。通过将紫外线辐射反应材料施加到印刷用的图案化的转移表面上，使得所述图案化的转移表面的润湿性和印刷转移性得到增强。在将印刷材料转移到基板的过程中，紫外线激发所述紫外线辐射反应材料。该技术能够增加印刷精度，并且可用于将印刷材料转移到基板上，以在印刷基板上建立印刷电路部件(如电路走线)和印刷电路元件。在一个特定的构造中，紫外线辐射反应材料可以由自由基引发剂或偶氮苯材料组成。The present invention relates to a printing method using a structure coated with ultraviolet radiation responsive material. Wetting and print transfer from a printing patterned transfer surface is enhanced by applying an ultraviolet radiation responsive material to the patterned transfer surface. Ultraviolet activation of the ultraviolet responsive coating is performed during a transfer of printing material to a substrate. The technique increases precision of the printing process and is useful for transfer of printing material to a substrate in order to establish printed circuit components such as circuit traces and printed circuit elements on the substrate. In a particular configuration the ultraviolet radiation responsive material can be made of azobenzene material or free radical initiators

Approach of Color Image Edge Detection Based on Color Tracking

传统的边缘检测方法大都是基于灰度图像的,用于彩色图像边缘检测时效果往往不能令人满意.本文提出了一种新的彩色边缘检测算法,它充分考虑了彩色图像的边缘特性,使用彩色差进行跟踪,从而弥补了传统边缘检测方法检测时丢失边缘的不足.通过与其它成熟的边缘检测技术进行比较,结果显示:该算法能提取更多的彩色边缘信息,而且检测精度和效果都比较令人满意,具有一定的实用价值和良好的处理效果.The traditional methods of detecting edges are mostly based on gray images,which did not satisfy in detecting color image edges.In this paper,a new algorithm for detecting color image edge is presented.The new algorithm is based on color tracking and it focused on the property of edge.By comparisons with other well-established technologies for edge detection,the result shows that the new algorithm has practical value and better effect and it observes more color edge information and its detecting precision and effectiveness are satisfying

Synthesis and Crystal Structure of Fe_2BP_3O_12

采用固态反应方法合成了有序的铁基硼磷酸盐Fe2BP3O12,用X射线粉末衍射方法精修了其晶体结构,属三方晶系,空间群为P3,α=8.02703(6)°A,c=7.40168(9)°A,V=413.02(1)°A3,Dx=3.2758(1)(g/Cm3),Z=2,对于55个参数,用188条衍射线及18001个衍射强度全谱数据点精修到R(Ⅰ)=6.35％,R(p)=15.36％,所对应的R(dbw)=10.12％.B原子具有三角形氧配位,P和Fe的氧配位分别是四面体和八面体.Fe的两配位八面体共面形成新结构单元,BO3三角形联接磷氧和铁氧多面体形成三维结构.对比同构的铬硼磷酸盐,此化合物期望具有类似的非线性光学及其它非线性物理性质.Fe2BP3O12 was synthesized by high temperature solid state reactions. Its crystal structure was refined by powder X-ray diffraction methods, belonging to trigonal system with space group P3, α=8.02703(6)°A, c=7.40168(9)°A, v=413.02(l)°A3, Dx=3.2758(l)(g/cm3), Z=2. The full profile refinement resulted to R(Ⅰ)=6.35%, R(p)=15.36% and R(dbw)=10.12% for 55 parameters using 188 reflections and 18001 profile data points. The structure contains [BP3O12]4-poly-anion, built by trigonal planar BO3 sharing the three corner oxygen atom with three PO4 tetrahedra. And Fe2O9 bi-octahedra fused by two face-sharing FeO6 connect with the poly-anions forming three dimensional ordered structure. Compared with its chromium isotypic compound, Cr2BP3O12, which shows NLO property, the title compound may be a potential NLO material.国家自然科学基金委杰出青年基金(20025101);上海市光科技发展基金(022261015);国家科技部863计划(2002AA324070