530 research outputs found

    Ultraquantum magnetoresistance in Kramers Weyl semimetal candidate β\beta-Ag2Se

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    The topological semimetal β\beta-Ag2Se features a Kramers Weyl node at the origin in momentum space and a quadruplet of spinless Weyl nodes, which are annihilated by spin-orbit coupling. We show that single crystalline β\beta-Ag2Se manifests giant Shubnikov-de Haas oscillations in the longitudinal magnetoresistance which stem from a small electron pocket that can be driven beyond the quantum limit by a field less than 9 T. This small electron pocket is a remainder of the spin-orbit annihilatedWeyl nodes and thus encloses a Berry-phase structure. Moreover, we observed a negative longitudinal magnetoresistance when the magnetic field is beyond the quantum limit. Our experimental findings are complemented by thorough theoretical band structure analyses of this Kramers Weyl semimetal candidate, including first-principle calculations and an effective k*p model.Comment: A new version based on arXiv:1502.0232

    Ghost Dog

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    The single crystal of the extra-large pore zeolite, ITQ-33, was obtained and used to explore its crystal structure details. The ITQ-33 structure was found to be disordered with the columnar periodic building unit, explaining the morphology changes upon the different Si/Ge ratio, and the formation of the hierarchical structure from assembling of ITQ-33 nanofibers

    Self-Imaging of Molecules from Diffraction Spectra by Laser-Induced Rescattering Electrons

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    We study high-energy angle-resolved photoelectron spectra of molecules in strong fields. In an oscillating laser electric field, electrons released earlier in the pulse may return to recollide with the target ion, in a process similar to scattering by laboratory prepared electrons. If midinfrared lasers are used, we show that the images generated by the returning electrons are similar to images observed in typical gas-phase electron diffraction (GED). These spectra can be used to retrieve the positions of atoms in a molecule as in GED. Since infrared laser pulses of durations of a few femtoseconds are already available today, the study of these high-energy photoelectrons offers the opportunity of imaging the structure of transient molecules with temporal resolution of a few femtoseconds

    Signature of Ericson Fluctuations in Helium Inelastic Scattering Cross Sections Near the Double Ionization Threshold

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    We calculated the inelastic electron impact excitation cross sections of He⁺ by electrons for a model helium atom to examine the onset of the signature of quantum chaotic scattering in this simple system. We find Ericson fluctuations (EF) in the calculated inelastic scattering cross sections only when the impact energies lie within about 0.21 eV below the double ionization threshold. We also discuss the stringent requirements and the proper methods for analyzing the inelastic scattering cross sections in order to observe EF experimentally

    Prognostic modeling of glioma using epilepsy-related genes highlights PAX3 as a regulator of migration and vorinostat sensitivity

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    This study aimed to construct and validate a prognostic model for glioma based on epilepsy-related genes (ERGs) and to investigate the functional role of PAX3 in glioma progression and drug response. Transcriptomic and clinical data from TCGA, GEO, and CGGA databases were used to identify differentially expressed ERGs between glioma patients with and without epilepsy. Univariate Cox regression, LASSO regression, and multivariate Cox analysis were employed to establish a four-gene prognostic model comprising PAX3, RETN, VEPH1, and HTR1A. Patients were stratified into high- and low-risk groups based on the median risk score, which was calculated using gene expression levels and corresponding regression coefficients. The model showed robust prognostic performance, with AUC values exceeding 0.85 in the training set and remaining above 0.73 in internal and external validation cohorts. Kaplan–Meier survival analysis demonstrated significantly longer overall survival in the low-risk group. The risk score was also validated as an independent prognostic factor across multiple datasets. A nomogram integrating clinical features and risk score further improved prediction accuracy, with C-index values up to 0.843 and high calibration concordance. Among the ERGs, PAX3 showed the strongest correlation with the risk score and was overexpressed in glioma, where it promoted proliferation, migration, epithelial–mesenchymal transition, and resistance to vorinostat through regulation of HDAC1/2/3 targets, as confirmed by functional assays showing that PAX3 knockdown suppressed proliferation and migration, while overexpression enhanced these effects. In conclusion, this study developed and validated a four-gene ERG-based prognostic model with high clinical utility and identified PAX3 as a potential therapeutic target that drives glioma cell migration and vorinostat sensitivity
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