Drug Addicts Mental Health Conditions and Their Relations with Relapse Reasons

目的: 通过对比研究探讨吸毒者的自尊、抑郁、焦虑等心理健康状况及其复吸原因。方法: 采用自尊量表、Carrol 抑郁量表(CRS)、状态- 特质焦虑问卷及复吸原因问卷, 对260 名吸毒类及经济类劳教人员进行问卷调查。结果: ①吸毒者的自尊与抑郁、焦虑评分均呈显著负相关。不同教养类型的劳教人员在抑郁, 焦虑维度上差异显著, 吸毒者, 尤其女性程度更高; ②在复吸原因选择上, 心理因素是复吸者选择最多的因素, 且复吸原因与心理状况呈显著相关。结论: ①吸毒者的自尊、抑郁以及焦虑等心理健康状况之间存在显著相关, 吸毒者, 尤其是吸毒女性的抑郁、焦虑程度明显高于其它劳教人员; ②心理因素是导致吸毒者复吸的重要原因, 而复吸原因又与吸毒者心理健康状况相互关联。该研究提示了在这一领域进行深入探讨的必要性

纳米酶在疾病治疗中的最新进展

纳米酶是具有酶催化活性的纳米材料,对比天然酶,纳米酶具有价格便宜、制备工艺简单、稳定性好、循环利用率高等优势.早期的纳米酶研究主要集中在检测方面,包括检测离子、小分子、核酸、蛋白质、癌细胞等,随着对纳米酶的深入了解,研究人员发现纳米酶在疾病治疗领域也具有巨大的应用前景.本论文将介绍纳米酶在细菌感染、炎症、癌症、神经退行性疾病等治疗领域的最新研究进展

Anatomical Variation of the Origin of the Right Renal Artery : Assessment with an Angle of the Origin and Ventral Protrusion

The right renal artery has been considered to originate laterally from the anterior aspect of aorta. In some cases, it turns more ventrally than the aorta, which can lead to intraoperative right renal artery injury. For this reason, we evaluated how the right renal artery turns ventrally and analyzed the factors for ventral protrusion of the right renal artery. We examined contrast-enhanced computed tomography images of 195 individuals and measured their angles of the right renal artery and ventral protrusion from the aorta. Age and sex had no significant correlation with these variations. A weaknegative correlation was found between body mass index and these variations. Almost all the right renal artery originated from the ventral side of the aorta, and almost half the right renal artery arose ventrally more than the aorta. Careful attention should be paid to ventral protrusion of the right renal artery to prevent vascular injury during surgery using the anterior approach to the upper retroperitoneum

目标跟踪的视觉注意计算模型

借鉴心理学中有关视觉注意的研究成果，提出一种应用于视频图像序列的注意焦点计算模型。针对Itti 模型算法计算复杂度高、 运算速度慢等缺点，通过对注意焦点的跟踪来降低计算量，实现注意焦点的实时监测。利用相邻帧之间的相似性，通过加权颜色直方图， 以最大匹配度作为预测模型，得到下一帧注意焦点的位置。实验结果表明，该注意焦点计算鲁棒性较好，可以满足动态场景实时监测的 需要。国家“863”计划基金资助项目(2006AA 01Z129)；国家 自然科学基金资助项目(60672018

Preliminary Study on Linking Land Use & Landscape Pattern and Water Quality in the Jiulong River Watershed

选取亚热带中尺度流域九龙江为研究对象,运用空间分析与统计分析方法,从全流域和河岸缓冲区尺度分别建立了九龙江流域2002年和2007年土地利用、景观格局与河流水质的关联.结果表明,2002年和2007年土地利用/景观格局-水质的关联基本一致,表现为建设用地面积比例与bOd5、nO 3--n、nH 4+-n和高锰酸盐指数呈负相关,与dO呈负相关;林地面积比例与nO 3--n、nH 4+-n和高锰酸盐指数呈负相关;耕地与nO 3--n、nH 4+-n和高锰酸盐指数呈负相关性.景观多样性指数(SHdI)与高锰酸盐指数、TP、nH 4+-n呈正相关,与dO呈负相关;最大斑块指数(lPI)与bOd5、高锰酸盐指数、TP和nH 4+-n呈负相关,而与dO呈正相关;斑块密度(Pd)与bOd5、TP和nH 4+-n呈正相关;但其它的景观指数与水质的关联无法被合理地解释.相对于全流域,缓冲区的土地利用面积比例和景观指数与河流水质的关联更为显著,因为大部分水质参数在缓冲区都能被更好地解释,表现在调整判定系数AdJuSTEd r2更大;土地利用面积比例比景观指数能够更好地预测水质,表现在大部分水质参数与土地利用面积比例有较好的相关关系.Geospatial analysis and statistical analysis were integrated to link land use & landscape pattern and water quality in 2002 and 2007 at the entire watershed and buffer zone scale in the Jiulong River Watershed.Results show that the relationships between land use & landscape pattern and water quality in 2002 and 2007 were basically consistent,namely: ① Percentage of built-up area was positively correlated with BOD5,NO3--N,NH 4+-N and permanganate index,and negatively correlated with DO;percentage of woodland area was positively correlated with NO3--N,NH 4+-N and permanganate index;percentage of cropland area was negatively correlated with NO3--N,NH 4+-N and permanganate index.② SHDI was positively correlated with permanganate index,TP,NH 4+-N,and negatively correlated with DO at the entire watershed and buffer scale;LPI was negatively correlated with BOD5,permanganate index,TP and NH 4+-N,and positively correlated with DO at the entire watershed and buffer zone scale;PD was positively correlated with BOD5,TP and NH 4+-N;Most of the landscape pattern metrics was not the good predictors for water quality in study watershed.③ Water quality parameters in buffer zone area have more significant correlations with percentage of land use type areas and landscape pattern metrics,because most water quality parameters in the buffer zone can be better explained with greater adjusted coefficient of determination(Adjusted R2).④ Compared to landscape pattern metrics,percentage of land use type area can predict water quality better because most water quality parameters have more stable correlations.国家自然科学基金项目(40901100;40810069004);福建省自然科学基金项目(2009J01222

巨噬细胞移动抑制因子在原发性肝癌中的临床意义

【目的】探讨肝癌患者血清巨噬细胞移动抑制因子（macrophage migration inhibitory factor,MIF）水平与其临床特征及预后的关系。【方法】用酶联免疫吸附法检测2004年1月至2006年5月60例确诊初治的原发性肝癌患者的血清MIF水平,并与30例健康人相比较,分析其与临床特征及预后的关系。【结果】原发性肝癌患者血清MIF水平较健康对照组显著升高（中位值,34.1ng/mL与15.9ng/mL,P〈0.001）。血清MIF水平与血管侵犯（P=0.014）、进展的临床TMN分期（P=0.037）及转移（P=0.026）密切相关。血清MIF高（〉34.1ng/mL）的患者2年生存率较血清MIF低的患者（≤34.1ng/mL）明显降低（59%与28%,LogRank为6.02,P=0.014）。多因素分析表明MIF水平是影响患者生存的独立预后因素。【结论】MIF可能参与了原发性肝癌的疾病进展过程,提示MIF在原发性肝癌患者中可作为反应肿瘤侵袭及预后的一个有用的生物标记物

Visual Attention Computational Model Based on Tracking Target

中文摘要：借鉴心理学中有关视觉注意的研究成果，提出一种应用于视频图像序列的注意焦点计算模型。针对Itti 模型算法计算复杂度高、运算速度慢等缺点，通过对注意焦点的跟踪来降低计算量，实现注意焦点的实时监测。利用相邻帧之间的相似性，通过加权颜色直方图，以最大匹配度作为预测模型，得到下一帧注意焦点的位置。实验结果表明，该注意焦点计算鲁棒性较好，可以满足动态场景实时监测的需要。 英文摘要：This paper proposes a model of the focus of attention in video sequences. The Itti model has the complex and slow computation, so it reduces computation to monitor the focus of attention through tracking the focus of attention. It uses the similarity between the adjacent frames,establishes the color histogram, selects the maximum similarity as predicable model, and gets position of the focus of attention in the next fame. The experimental results indicate that this model is effective in robustness and real-time.基金项目：国家“863”计划基金资助项目(2006AA 01Z129)；国家自然科学基金资助项目(60672018

B细胞淋巴瘤SHP-1基因甲基化状态及其意义

【目的】探讨JAK/STAT信号转导途径负调控子SHP-1基因启动子区域CpG岛异常甲基化在B细胞淋巴瘤中的意义。【方法】收集存档石蜡包埋组织标本61例(52例B细胞非霍奇金淋巴瘤标本,9例良性增生淋巴结标本),健康人外周血单个核细胞DNA标本15例,用甲基化特异性PCR(methylation-specific PCR,MSP)和非甲基化特异性PCR(unmethylation-specific PCR,un-MSP)检测SHP-1启动子区域CpG岛甲基化状态,MSP、un-MSP和RT-PCR方法分别检测接受或未接受去甲基化处理的Burkitt淋巴瘤细胞系Raji的甲基化状态及mRNA的表达,MTT法检测接受去甲基化干预后细胞生长受抑情况。【结果】SHP-1基因启动子区域在弥漫性大B细胞淋巴瘤和滤泡性淋巴瘤甲基化频率分别为94%及97%,对照组9例淋巴结良性增生标本和15例正常人外周血单个核细胞标本中SHP-1基因启动子区域甲基化频率为0。经去甲基化干预后,Raji细胞SHP-1基因启动子区域呈去甲基化状态,基因恢复表达,细胞生长受到抑制。【结论】SHP-1基因启动子区域启动子区域CpG岛在B细胞淋巴瘤中存在高度甲基化，由其所致的SHP-1基因沉默可能是B细胞淋巴瘤发生的一个重要因素，SHP-1基因的甲基化可作为一个良好的分子诊断标记及可能的治疗靶点