213 research outputs found

    A Kind of Web Spreadsheets Based on POI

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    互联网技术的飞速发展使得基于Web的应用越来越普遍,同时也更加复杂。基于Web的动态Excel表格就是一个典型的实例。随着开发技术的不断发展,一些开源项目凭借其公开、自由以及免费等众多优势产生了越来越大的影响,很多项目都采用了开源技术。文中介绍了一种开源的基于Java的Excel报表开发组件POI引擎,阐述了其表格显示原理。通过在Web上实现动态Excel表格,给出了一种典型应用,并结合一个实际项目中的例子进行了分析,探索出了一种开发Web动态Excel表格的方法。With the development of Internet,Web application has been more popular and complicated.Dynamic Web spreadsheets is a typical case.With the development of developing technology,some open source projects become more infective for open and free,and are implemented in many projects.This paper introduces a kind of open source implementing dynamic spreadsheets on Web based on POI engine,describes the display theory of POI.This paper gives a typical application,analyses with an example in a practical project and finds a way to develop dynamic spreadsheets.国家985二期信息创新平台项目(0000-X07204

    从规则中艺术分的变化态势思考中国技巧运动的发展

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    通过对1979-2004年技巧规则中艺术分条文变化态势的分析及多次在世界大赛上与诸技巧运动强国优秀选手同场竞技、远程观摩历届大赛的基础上,提出重视具有远见性地深解并应用规则的艺术性的评分条文是中国技巧运动继续保持世界先进水平的一个重要因素

    Research on Image Recognition Basd on BP Neural Network

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    BP神经网络具有较强的容错性和自适应学习能力,因而在数字图像识别领域有着广泛的应用。本文在经典BP神经网络的基本算法的基础上,对BP算法的参数设置进行了优化,实现了一种基于分类的改进BP神经网络算法。通过探讨BP神经网络在数字图像分类识别中的应用,详细考察了各种参数对识别效果的影响。实验结果证明改进后的算法有很好的实用价值。Back-propagation neural network with high fault-tolerance and good adaptive learning ability,is found great applications in digital image recognition.This paper presents an improved algorithm through setting new parameters based on traditional BP algorithm,applies it to digital image recognition and analyzes the influence produced by improved parameters.The experimental result shows that the improved algorithm has a certain practical value.国家985二期信息创新平台项目(0000-X07204

    Progress of C_2-Symmetric Biphenyl Bisphosphine Ligands Ⅲ

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    手性膦配体的合成及其在手性诱导催化反应中的应用一直是不对称合成与催化研究中非常重要的研究领域之一。近10年来,大量的C2-轴对称手性双膦配体被合成出来并成功地应用于不对称催化研究,本文从C2-轴对称联苯类手性双膦配体的介绍、合成方法、C2-轴对称联苯类手性双膦配体在不对称催化氢化、以及其在其他不对称诱导反应中的应用4个方面综述了相关研究进展,并对今后配体的合成及应用前景进行了展望。A vast number of biphenyl atropisomeric diphosphine ligands are successfully applied in asymmetric catalysis.The synthesis and applications of this type of ligands are a continuous interesting theme in organic chemistry.This review describes recent progress in synthesis and application of C2-Symmetric diphosphine ligands on the asymmetric catalysis hydrogenation and other asymmetric induced reaction,and the future ligand synthesis and application prospect.国家自然科学基金(20272037); 教育部博士点基金(20080610022); 四川自然科学基金重点项目(07ZA109

    Progress of C_2-Symmetric Biphenyl Bisphosphine LigandsⅡ

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    手性膦配体的合成及其在手性诱导催化反应中的应用一直是不对称合成与催化研究中非常重要的研究领域之一。近十年来,大量的C2-轴对称手性双膦配体被合成出来并成功地应用于不对称催化研究,本文从C2-轴对称联苯类手性双膦配体的介绍、合成方法、C2-轴对称联苯类手性双膦配体在不对称催化氢化以及其在其他不对称诱导反应中的应用4个方面综述了相关研究进展。A vast number of biphenyl atropisomeric diphosphine ligands have been successfully applied in asymmetric catalysis.The synthesis and applications of this type of ligands are a continuous interesting theme in organic chemistry.This review describes recent progress in synthesis and application of C2-Symmetric diphosphine ligands on the asymmetric catalysis hydrogenation and other asymmetric induced reaction.国家自然科学基金(20272037); 教育部博士点基金(20080610022); 四川自然科学基金重点项目(07ZA109

    Progress of the Study on C_2-symmetric Biphenyl Bisphosphine Ligands(一)

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    手性膦配体的合成及其在手性诱导催化反应中的应用一直是不对称合成与催化研究中非常重要的研究领域之一。近10年来,大量的C2-轴对称手性双膦配体被合成出来并成功地应用于不对称催化研究,本文从C2-轴对称联苯类手性双膦配体的介绍、合成方法,C2-轴对称联苯类手性双膦配体在不对称催化氢化,以及其在其他不对称诱导反应中的应用4个方面综述了相关研究进展,并对今后配体的合成及应用前景进行了展望。A vast number of biphenyl atropisomeric diphosphine ligands are successfully applied in asymmetric catalysis.The synthesis and applications of this type of ligands are a continuous interesting theme in organic chemistry.This review describes recent progress in synthesis and application of C2-Symmetric diphosphine ligands in the asymmetric catalysis hydrogenation and other asymmetric induced reaction.And the future ligand synthesis and application are predicted.国家自然科学基金(20272037); 教育部博士点基金(20080610022); 四川自然科学基金重点项目(07ZA109

    Curcumin-induced Apoptosis Affects the Expression and Localization of hnRNP A2/B1 in Human Osteosarcoma MG-63 Cells

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    姜黄素(CurCuMIn)诱导处理的人成骨肉瘤Mg-63细胞,在光镜和电镜观察细胞凋亡的基础上,对HnrnP A2/b1在核基质中存在、分布及其与凋亡相关基因产物在Mg-63细胞中的共定位关系进行了研究.经姜黄素处理后,细胞出现染色质凝聚、细胞核固缩、凋亡小体等典型的细胞凋亡形态特征;双向凝胶电泳和质谱鉴定结果显示,HnrnP A2/b1存在于Mg-63细胞核基质蛋白组分中,在姜黄素处理后细胞核基质蛋白中表达下调.蛋白质印迹杂交结果,证实HnrnP A2/b1在姜黄素处理前后的Mg-63细胞核基质蛋白中的存在及其表达下调变化.免疫荧光显微镜观察显示,HnrnP A2/b1定位于Mg-63细胞核基质纤维上,经姜黄素处理后出现分布位置与表达水平变化.激光扫描共聚焦显微镜的观察结果显示,HnrnP A2/b1在Mg-63细胞凋亡过程中与bAX、bCl-2、fAS和P53等基因产物具有共定位关系,且其共定位区域发生了变化.研究结果证实了HnrnP A2/b1定位于核基质纤维上,是一种核基质蛋白,在姜黄素诱导人成骨肉瘤Mg-63凋亡过程中的表达与分布变化及其与凋亡相关基因的关系显然对Mg-63细胞凋亡具有重要影响,这为深入揭示肿瘤细胞凋亡的机制提供了重要科学依据和深入探索的新方向.The morphology of human osteosarcoma MG-63 cells under light microscopy and transmission election microscopy was altered when treated with curcumin.The distribution of heterogeneous nuclear ribonucleoprotein (hnRNP)A2 /B1 in the nuclear matrix and its colocalization with the apoptosis-related gene products were examined.The results demonstrated that curcumin induced typical apoptotic responses,such as chromatin agglutination,nuclei condensation,and apoptotic body formation.Twodimentional PAGE and mass spectrum analyses showed that hnRNP A2 /B1 was complexed with the nuclear matrix.Confirmed by Western blotting,curcumin treatment resulted in a down-regulation of hnRNP A2 /B1 expression.An altered distribution of hnRNP A2 /B1 with the nuclear matrix was observed in immunofluorescence assays.Laser confocal microscopy showed that hnRNP A2 /B1 colocalized with apoptosis-related molecules,including Bax,Bcl-2,Fas and p53,with different patterns before and after curcumin treatments.Our study showed that expression level and the distribution of hnRNP A2 /B1,a nuclear matrix protein,were altered by curcumin treatments and mought be involved in the process of apoptosis in MG-63 cells.国家自然科学基金项目(No.30871241)---

    异体骨结合骨髓间质干细胞移植治疗骨缺损的动物实验

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    【目的】研究使用异体骨混合骨髓间质干细胞移植治疗骨缺损的可行性及动物实验初步结果。【方法】将15只新西兰白兔双侧桡骨造成1 cm骨缺损模型,随机选择同一只动物的一侧为实验侧,自体配对的另一侧为对照侧。将表面脱钙的同种异体骨和来源于受体的体外培养增殖的骨髓间质干细胞混合植入实验侧骨缺损,对照侧仅植入同样制作的异体骨。12周后,进行X线检查、生物力学检查和组织学检查,将结果进行对比。【结果】动物在术后12周,实验侧X线片光密度测量结果,破坏载荷时扭矩和扭角测量结果均优于对照侧;组织学评分中,实验侧骨痂量评分优于对照侧,骨连接成熟程度和骨髓发育程度两者没有明显差异。【结论】骨髓间质干细胞可以促进异体骨在移植后的成骨作用,在增多成骨量的同时不影响骨组织发育
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