Observation on the Clinical Effect of Shiduqing Combined with Ebastine in the Treatment of Atopic Dermatitis

目的观察湿毒清和依巴斯汀联合应用治疗特应性皮炎的临床疗效以及治疗前后外周血EOS、血清Ig E水平的变化情况。方法将我科94例特应性皮炎患者随机分为治疗组和对照组,每组47例,对照组患者使用依巴斯汀口服,治疗组患者加用湿毒清胶囊口服,观察治疗后对照组和治疗组的临床疗效及外周血EOS、血清Ig E的水平变化。结果对照组患者治疗总有效率为63.83%,治疗组总有效率为93.62%,具有显著性差异(P<0.05),治疗后治疗组血清Ig E水平与治疗前及对照组相比均呈明显下降趋势(P<0.05),具有统计学意义。结论湿毒清联合依巴斯汀口服治疗特应性皮炎比单纯口服依巴斯汀的治疗效果更加显著

Effectivity and safety of three common antisyphilic drugs in treatment of early syphilis

目的观察3种驱梅药物治疗早期梅毒的临床治疗效果。方法选取2007年1月~2013年3月厦门大学附属第一医院门诊收治的早期梅毒患者共90例。随机将入选患者分为3组,分别是苄星青霉素组,克拉霉素组以及阿奇霉素组。观察比较3组患者的治疗效果,包括皮损的改善起效时间、皮损的痊愈时间及TruST转阴情况。结果 3组患者驱梅药物在一期梅毒治疗的平均皮损起效时间显示,苄星青霉素组与克拉霉素组、克拉霉素组与阿奇霉素组间比较差异均有统计学意义(T=14.603,P<0.05;T=12.682,P<0.05);而无论在一期梅毒治疗或二期梅毒治疗,3组患者的平均皮损痊愈的时间对比均没有显著性差异,二期梅毒患者平均皮损起效时间比较差异无统计学意义。苄星青霉素和克拉霉素的TruST转阴率为100%,阿奇霉素的转阴率为96.7%,但差异无统计学意义。结论苄星青霉素、克拉霉素和阿奇霉素的治疗效果相当,对于青霉素过敏的患者可以考虑采用克拉霉素和阿奇霉素进行早期梅毒治疗,能够取得满意的治疗效果。Objective To observe the clinical effect of three antisyphilic drugs in the treatment of early syphilis.Methods From January 2007 to March 2013,90 cases early syphilis in department of dermatology of our hospital were selected and randomly devided into three groups: benzathine penicillin group,clarithromycin group and azithromycin group.The efficacy including the onset time of improvement,recovery time of skin lesions and TRUST negative conversion rate were compared in three groups.Results The onset time of skin lesions improvement in patients with primary syphilis result showed that there was significant difference between benzathine penicillin and clarithromycin(t = 14.603,P < 0.05),clarithromycin and azithromycin(t = 12.682,P < 0.05).While in the treatment of primary syphilis and secondary syphilis,there were no significant differences among recovery time of skin lesions.And there were no significant differences the onset time of skin lesions improvement in treatment of secondary syphilis among three groups.The TRUST negative conversion rates of benzathine penicillin and clarithromycin both were 100%,and azithromycin was 96.7%,with no significant difference.Conclusion The antisyphilic efficacy of three drugs are similar.The patients allergic to penicillin may be treated with clarithromycin or azithromycin,who would aquaire a satisfied result.中华医学会2014年度中青年医师扶持计划(20140519

A Survey on the Human InFection of Phthiriu Pubis From Xiamen

于1991年4月至1993年7月，经厦门市第一医院皮肤科门诊检查获知，染有阴虱或其虫卵者计55例，其中男性32例，占58.18%，女性23例，占41.82%。年龄最小18岁，最大60岁，以21~30岁最多，占63.63%，职业分析以工人多见，占38；18%，传播途径认为与性生活混乱有关.During 1991～1993,about 55 human cases of pubic louse inFections werediagnosed in the Skin Department of Xiamen First Hospital.Among these cases,58;18%(32cases)was male amd 41.82%(23 cases)was Female,The youngest one was 18 uears old and theoldest 60 years old,while the majority of them belonged to the 21～30 year group(63.63%).Besides,the occupation records showed that 36.18%was worker,and 21.8%was cadre.Thedispersal pattem would be believed to be concerned with mixed sexuality

Measurement of integrated luminosity of data collected at 3.773 GeV by BESIII from 2021 to 2024

We present a measurement of the integrated luminosity e+e- of collision data collected by the BESIII detector at the BEPCII collider at a center-of-mass energy of Ecm = 3.773 GeV. The integrated luminosities of the datasets taken from December 2021 to June 2022, from November 2022 to June 2023, and from October 2023 to February 2024 were determined to be 4.995±0.019 fb-1, 8.157±0.031 fb-1, and 4.191±0.016 fb-1, respectively, by analyzing large angle Bhabha scattering events. The uncertainties are dominated by systematic effects, and the statistical uncertainties are negligible. Our results provide essential input for future analyses and precision measurements

Determination of the number of ψ(3686) events taken at BESIII

The number of ψ(3686) events collected by the BESIII detector during the 2021 run period is determined to be (2259.3±11.1)×106 by counting inclusive ψ(3686) hadronic events. The uncertainty is systematic and the statistical uncertainty is negligible. Meanwhile, the numbers of ψ(3686) events collected during the 2009 and 2012 run periods are updated to be (107.7±0.6)×106 and (345.4±2.6)×106, respectively. Both numbers are consistent with the previous measurements within one standard deviation. The total number of ψ(3686) events in the three data samples is (2712.4±14.3)×10^