Highly efficient enrichment of phosphopeptides using porous zirconium-phytic acid hybrid

Highly efficient enrichment of phosphopeptides using porous zirconium-phytic acid hybri

Synthesis of polymeric capillary monoliths via thiol-maleimide polymerization reaction for highly efficient capillary chromatographic separation

Synthesis of polymeric capillary monoliths via thiol-maleimide polymerization reaction for highly efficient capillary chromatographic separatio

一种含多面体寡聚倍半硅烷试剂的杂化整体材料的制备

本发明涉及高分子领域，具体涉及一种基于自由基聚合制备有机－无机杂化多孔整体材料的方法，本发明首先是将含有多个双键的多面体寡聚倍半硅烷试剂和引发剂在致孔剂中超声溶解，在一定的温度下发生自由基聚合反应，原位形成多孔的杂化整体材料，然后将含有引发剂和有机功能单体的溶液通入整体材料，在一定温度下将有机功能单体化学键合在整体材料表面上，最终制备成具有不同表面性质和功能的杂化整体材料。所述的制备方法具有操作简便快速，反应条件温和等优点，另外还可以根据不用的应用要求选择不同的有机功能单体，无需调节致孔体系，即可制备多种有机－无机杂化整体材料

Click polymerization for preparation of monolithic columns for liquid chromatography

In recent years, polymerizations based on click reactions (thiol-ene, thiol-yne, thiol-Michael, thiol-epoxy and amine-epoxy) have been utilized to prepare monolithic columns. These polymerization systems are easily carried out under mild conditions. Either hybrid or organic monolithic columns fabricated by click polymerization demonstrated homogeneous network structures. For separation of small molecules, the column efficiencies, such as plate height with less than 10 gm, have been greatly improved comparing with organic monolithic columns prepared with free radical polymerization. In this review, we will summarize recent progress on the preparation of monolithic columns and their chromatographic performances. (C) 2016 Elsevier B.V. All rights reserved

柱亲和介质用于内毒素去除的研究

以琼脂糖凝胶为基质,采用不同方法活化后,键合多粘菌素B配基,制备了3种用于内毒素去除的亲和介质.亲和介质的配基键合量及对内毒素的去除率随间隔臂长度的增加而增加.考察了盐浓度、pH、温度及流速对亲和介质3去除内毒素的影响.结果表明,亲和介质3在NaCl 浓度为0.05～0.5 mol/L,pH为6～10,温度为25～55℃,流速为0.20～0.80 mL/min范围内对内毒素去除效果最佳,去除率大于90%

Click polymerization for preparation of monolithic columns in capillary liquid chromatography

Click polymerization for preparation of monolithic columns in capillary liquid chromatograph

用于生物样品分离的杂化毛细管整体住的制备

Preparation of Hybrid Monolithic Capillary Columns for Separation of Biological Sample