凝胶推进剂模拟液静电雾化行为规律研究

针对凝胶推进剂雾化困难的问题,引入静电喷射技术雾化凝胶推进剂。以水凝胶模拟液为介质,探究静电雾化技术的可行性及试验条件,当收集距离2~5 cm、供液速率10~30μL/h时,凝胶模拟液可实现稳定雾化,收集液滴直径小于100μm,散射角分布在8°~36°之间,收集液滴直径和散射角均随收集距离的增大和针管直径的减小而减小;同样条件下,凝胶粘度越小,散射角和雾化液滴直径越小。在此基础上,针对单针管推力小的问题,分析使用多针管喷头进行凝胶推进剂静电雾化的可行性及其雾化区域分布,结果表明2号凝胶模拟液用于多喷头雾化可得到良好的雾化区域分布,适用于凝胶推进系统之中。国防科技重点实验室基金项目(61427040203162704004

Co-Ni-W三元系相图的实验测定与热力学计算

本研究采用合金法、电子探针显微分析仪(EPMA)和X射线衍射(XRD)技术,对Co-Ni-W三元系在1 000℃和1 200℃下的等温截面相图进行了实验测定。结合本研究和已报道的相平衡实验信息,基于CALPHAD (Calculation of phase diagrams)方法,对Co-Ni-W三元系相图进行了热力学优化与计算,获得了自洽性良好的热力学参数,计算结果与实验数据取得了良好的一致性。国家重点研发计划(2016YFB0701401)~

类泛素蛋白及其中文命名

泛素家族包括泛素及类泛素蛋白,约20种成员蛋白.近年来,泛素家族领域取得了迅猛发展,并已与生物学及医学研究的各个领域相互交叉.泛素家族介导的蛋白质降解和细胞自噬机制的发现分别于2004和2016年获得诺贝尔奖.但是,类泛素蛋白并没有统一规范的中文译名. 2018年4月9日在苏州召开的《泛素家族介导的蛋白质降解和细胞自噬》专著的编委会上,部分作者讨论了类泛素蛋白的中文命名问题,并在随后的\"泛素家族、自噬与疾病\"(Ubiquitinfamily,autophagy anddiseases)苏州会议上提出了类泛素蛋白中文翻译草案,此草案在参加该会议的国内学者及海外华人学者间取得了高度共识.冷泉港亚洲\"泛素家族、自噬与疾病\"苏州会议是由美国冷泉港实验室主办、两年一度、面向全球的英文会议.该会议在海内外华人学者中具有广泛影响,因此,参会华人学者的意见具有一定的代表性.本文介绍了10个类别的类泛素蛋白的中文命名,系统总结了它们的结构特点,并比较了参与各种类泛素化修饰的酶和它们的生物学功能.文章由45名从事该领域研究的专家合作撰写,其中包括中国工程院院士1名,相关学者4名,长江学者3名,国家杰出青年科学基金获得者18名和美国知名高校华人教授4名.他们绝大多数是参加编写即将由科学出版社出版的专著《泛素家族介导的蛋白质降解和细胞自噬》的专家

戊型肝炎病毒中和性单克隆抗体的鉴定

阻断实验发现,用戊型肝炎病毒(HEV)衣壳蛋白重组抗原制备的8株抗HEV单克隆抗体(mAb),分别识别3个构象表位和2个线性表位。用抗体捕获反转录PCR方法证实,其中识别2个构象表位的3个mAb可以直接捕获HEV颗粒,表明这2个表位位于HEV颗粒的外表面。识别这两个表位的mAb8C11和8H3均可中和HEV对恒河猴的致病性和感染性。mAb8C11缩短排毒时间的效应较明显,而mAb8H3延迟机体抗HEV抗体阳转时间的效应较明显。二者的中和效应具有较明显的协同作用。中和单抗8C11、8H3对戊肝不同感染时期的血清均有显著阻断作用,Fab片段的阻断作用与完整抗体类似,表明这两个mAb对应的中和表位是HEV体液免疫应答的优势表位

Evaluation on difference of therapeutic efficacy of Jiawei Xiaoyao Granules and Pills in treatment of emotional disorder during perimenopause based on Greene Climacteric Scale

目的:在前期加味逍遥丸治疗围绝经期情绪障碍具有比较优势的基础上,基于grEEnE量表探讨其颗粒剂和丸剂不同剂型间疗效差异。方法:经筛选后患有情绪障碍的围绝经期女性75例随机等分为A、b、C3组,分别对应采用帕罗西汀、加味逍遥丸和加味逍遥颗粒剂治疗8周。所有患者在治疗前后各进行1次grEEnE及其子因子评定,并在观察期结束时进行TESS评定。结果:grEEnE总分差及其焦虑、抑郁因子分差:3种治疗方法均能改善,且相互间无显著差异;grEEnE性因子和血管因子分差:后二组均优于A组(P<0.01);TESS评分:与A组比较,b、C组均有统计学意义(P<0.01),评分均小于A组,且后二组间无显著差异。结论:加味逍遥的2种剂型间疗效无显著差异,考虑到帕罗西汀的不良反应,治疗该病加味逍遥的2种剂型都值得推荐。Objective: To investigate the difference in therapeutic efficacy between Jiawei Xiaoyao Granules and pills based on the preliminary research of treating emotional disorder during perimenopause with Jiawei Xiaoyao Pills and Greene Climacteric Scale.Methods: 75 female patients with emotional disorder during perimenopause were slected and randomly divided into 3 groups as group A, B and C.Patients in the 3 groups were treated with paroxetine, Jiawei Xiaoyao Pills and Jiawei Xiaoyao Granules respectively for 8 weeks.Greene and Greene factors assessment were carried out in all the patients before and after treatment, and the TESS assessment was carried out at the end of the observation period.Results: The three therapies all could improve the gap in total score of Greene and its factors as anxiety and depressed, and the difference among these three groups was no significant.The factors of Greene and gap in score of vascular factors of group B and C was better than that of group A(P<0.01).The difference in TESS score between group A and group B and C was significant(P<0.01), while the difference between group B and group C was not significant.Conclusion: The difference in curative effect between the two formulations was not significant.Because of the adverse reactions of paroxetine, in the treatment of emotional disorder during perimenopause, the two formulations of Jiawei Xiaoyao Powder were worth to be recommended.国家自然科学青年基金项目(No.81302960)~

Comparative Study of the American Research University System: The case of the University of California, Berkeley

This book approaches the administration and education system of American research universities. We focus on the University of California, particularly Berkeley campus. 2018 is the 150th anniversary of the University of California, whose history includes the successful development of 10 research-intensive campuses. We believe we can learn many things about the nature and development of research universities from this example. Indeed, this book is, in part, the outcome of a graduate course in “Comparative Higher Education Management” at the Graduate School of Education at the University of Tokyo. Student groups visited Berkeley Campus twice in 2014 and 2016. In each of our visits, we met with more than fifteen people and engaged in lecture and discussion sessions over the course of one week. This book has four parts. Part 1 is about the UC system. Chapter 1 presents a historical overview of changes in UC’s financial model. Chapter 2 discusses its Board of Regents. Part 2 focues on the management and organizational structure of Berkeley. Chapter 3 discusses OPA and IR. Chapter 4 focuses on the role of the Provost, the important position for academic governance unique to American research universities. Chapter 5 considers the Alumni Association, which plays a critical role in Berkeley’s financial strength. Part 3 discusses aspects of quality assurance and improvement. Chapter 6 describes the accreditation process by WASC, an institutional accreditation board of California. Chapter 7 analyses how internal quality assurance of undergraduate education works at Berkeley. Chapter 8 discusses research strategy and support at Berkeley, focusing on the work of BRDO. The three chapters of Part 4 concern undergraduate education and student support. Chapter 9 discusses the admissions process in the UC system. Chapter 10 focuses on how the Student Learning Center works. Chapter 11 discusses financial support for undergraduate students of Berkeley.本書の趣旨と概要… 福留東土 i 第1部 カリフォルニア大学システム 　第1章 カリフォルニア大学の財政の変遷… 長野公則 1 　第2章 憲法上独立な大学理事会は「社会の代表」か? ―カリフォルニア大学理事会を例に―… 中世古貴彦 11 第2部 マネジメントと組織 　第3章 カリフォルニア大学バークレー校のマネジメント構造―組織エコロジーモデルから見たIR 機能の変遷―… 平田光子 21 　第4章 プロボストの位置づけと役割… 丸山勇 31 　第5章 カリフォルニア大学バークレー校の同窓会戦略… 野村由美 45 第3部 質の保証と改善システム 　第6章 カリフォルニア大学バークレー校とWASC によるアクレディテーション… 諏訪猛 55 　第7章 学習成果に基づく内部質保証サイクルの考察―カリフォルニア大学バークレー校の取組を踏まえて―… 河本達毅 65 　第8章 カリフォルニア大学バークレー校の研究戦略と研究支援… 岩崎琢哉 75 第4部 学士課程教育と学生支援 　第9章 カリフォルニア大学システムの学士課程教育における入学者選抜制度―多様性を評価する入学者選抜の観点から―… 廣中洋祐 83 　第10章 カリフォルニア大学バークレー校の学習支援に関わる担い手の考察―Student Learning Center（SLC）の取組を中心に―… 蝶慎一 95 　第11章 アメリカにおける学生への経済支援―カリフォルニア大学バークレー校を事例に―… 王帥 10

专题:中国非正规经济(下)

李明欢以非正规雇佣为主要内涵的非正规经济之所以能够在跨国领域大行其道,根源之一在于全球化正如同由跨国资本把握方向盘的巨型“压路机“,力图突破一切不利于其扩张之国境边界,朝着政治和