The progress of surgical treatment for scoliosis associated with intraspinal anomalies

随着磁共振成像(magnetic resonance imaging,MRI)技术在脊柱外科中的广泛应用,包括拟诊为特发性脊柱侧凸(idiopathic scoliosis,IS)在内的许多脊柱侧凸畸形被发现合并有脊髓病变~([1、2])。目前,关于脊髓病变与脊柱侧凸之间的伴发关系仍不清楚。此外,对于此类合并脊髓病变的脊柱侧凸,在进行脊柱畸形矫正时是否需要处理伴发的脊髓病变、如何处理及何时处理等尚未达成共识。笔者就

Experimental research state of preventive and therapeutic effect of traditional Chinses medicine on gastrointestinal injury after stress

应激会破坏胃肠道的自稳态,引起胃肠道功能紊乱,轻则出现恶心、呕吐、厌食、腹泻、腹胀,甚则可致应激性溃疡,影响人们的工作生活和健康。单药、经方、自; 拟方和针灸等中医药干预可通过抗胃肠黏膜损伤、调整紊乱的胃肠激素等途径有效改善各种应激后胃肠损伤,文章对此作一综述,并发现迄今为止在中医药预防应激; 后胃肠损伤的抗应激相关机制研究尚显不足,值得进一步研究。Various kinds of stress would destroy gastrointestinal homeostasis and; lead to functional disturbances of gastrointestinal tract, such as; nausea, vomiting, anorexia, diarrhea, abdominal distention and even; stress ulcer, which could influence the work, life and health of people; suffered from stress. Classical prescription, self-made prescription and; acupuncture could ameliorate symptoms and signs of gastrointestinal; stress reaction effectively by protecting from gastrointestinal mucosa; injury and regulating gastrointestinal hormones. This article reviewed; those researches and found that, so far, there were shortages of TCM in; prevention effect and mechanism of anti-stress, which deserved further; study.国家自然科学基金项目; 福建省自然科学基金项

Clinical application of tongue diagnosis and Xiang

象思维是中医学的核心思维,而舌象则是现阶段象思维现代化的突破点。在大数据时代背景下,以象思维的概念为切入口,结合各个象的视野和盲区,通过阐述舌象; 和象思维在诊断、治疗和预防上的应用,紧跟时代的步伐,促进理论在实际临床上的运用。Xiang is the core thinking of traditional Chinese medicine, the tongue; manifestation is the breakthrough point of modernization of Xiang at the; present stage. In the background of large data age, taking the concept; of Xiang as the entrance, combining the visual field and the blind area; of different Xiang, and elaborating the application of tongue; mannifestation and Xiang in diagnosis, treatment, and prevention,; following the pace of time, in order to promote the application of; theory in clinic.厦门市科技计划项

Experience of professor WANG Yan-hui's in treating tumor based on ‘tumor is the pathologic products'

王彦晖教授在多年的肿瘤诊疗过程中发现肿瘤与中医学之“病理产物“在病因、病位、病症方面有诸多共性,从而提出“肿瘤都是病理产物“的观点以指导治疗,强调治疗当以“祛除病理产物“为法,并且具体处方用药有4个特点:1祛邪贯穿治疗始终;2理气、化痰、祛瘀并用;3大剂量用药,功效突出;4持法守方。王教授以此治疗各种恶性肿瘤,验之有效,值得推广。Professor WANG Yan-hui has found that tumor and pathologic products have some qualities in common such as pathogenesis, location and symptom, so he proposes that tumor is the pathologic products.He emphasizes on the law of ‘eliminating pathologic products' in tumor's treatment.There are four characteristics in his prescription and medication as follows: 1eliminating pathology has always been throughout in the treatment, 2combination of regulation qi, dissolving phlegm and removing blood stasis, 3large dose medication, 4keeping the same law and prescription.This theory has been proved by professor WANG in his practices which is worth for learning

各种应激源对胃肠相关功能影响的研究进展

应激源指对机体构成任何威胁的刺激,包括物理（低温、高温等）、化学、机械、心理、社会等各种刺激。应激源作用于人体产生的非特异性应答反应称为应激。适当的应激可以促进机体逐步适应环境,而过度的应激则使机体正常稳态被破坏,发生一系列非特异性损害。胃肠道是机体与外界接触面积最大的器官,且由于其黏膜血管的解剖特点,在应激状态下更容易受影响,其中,肠道为多器官功能障碍的始动器官。国家自然科学基金项目（No.81302876）; 福建省自然科学基金项目（2013J05123

Effects of Ciji Hua'ai Baosheng Decoction on peripheral blood cells and spleen hematopoietic growth factors of tumor chemotherapy model mice with H22 hepatoma carcinoma cells

目的:研究慈济化癌保生汤(CHBT)对H22肝癌化疗小鼠外周血细胞以及脾脏造血生长因子红细胞生成素(EPO)、粒细胞-巨噬细胞集落刺激因子(GM-CSF)以及造血功能的作用。方法:将肝癌H22细胞悬液(2×107/m L)接种于Kunming种小鼠右前腋皮下,约7d后,全部形成移植瘤,环磷酰胺(CTX)按200mg/kg(0.2m L/10g)腹腔注射,建立H22肝癌小鼠化疗模型。随机分为模型组,CTX(0.033g/kg)组,CHBT高、中、低剂量(117、58.5、29.25g/kg)组,连续给药10d,采用全自动血细胞分析仪检测外周血红细胞、白细胞、血小板和血红蛋白,运用酶联免疫吸附测定法检测脾组织EPO和GM-CSF含量。结果:与模型组和CTX组比较,CHBT高、中、低剂量组红细胞、白细胞、血小板数量明显升高(P<0.05,P<0.01);CHBT高、中剂量组血红蛋白升高(P<0.05,P<0.01);CHBT各剂量组EPO、GM-CSF含量升高(P<0.01,P<0.05)。结论:慈济化癌保生汤能促进化疗后EPO和GM-CSF的生成并增强活性,刺激血细胞的产生,维持外周血象稳定性。Objective: To investigate the effects of Ciji Hua'ai Baosheng Decoction(CHBT) on peripheral blood cells, spleen hematopoietic growth factors such as erythropoietin(EPO) and granulocyte-macrophage colony stimulating factor(GM-CSF), and blood-producing function of tumor chemotherapy model mice with H22 hepatoma carcinoma cells. Methods: The suspension of H22 hepatoma carcinoma cells(2×107/m L) were subcutaneously injected into the right anterior armpit of Kunming mice. After 7 days, all mice formed the transplanted tumors, and then the cytoxan(CTX) at the dosage of 200mg/kg were intraperitoneally injected into the mice to establish the tumor chemotherapy model. The mice were randomly divided into model group, CTX(0.033g/kg) group, CHBT high, middle and low dose(117, 58.5, 29.25g/kg) groups. The experiment groups were treated for 10 days. The levels of red blood cells, white blood cells, platelet and hemoglobin in peripheral blood were detected by automatic blood cell analyzer. The contents of EPO and GM-CSF in spleen tissue were assayed by enzyme-linked immunosorbent assay. Results: Compared with model group and CTX group, the levels of red blood cells, white blood cells and platelet in high, middle and low dose CHBT groups were increased significantly(P<0.05, P<0.01), the levels of hemoglobin in CHBT high and middle dose groups were increased(P<0.05, P<0.01), the contents of EPO and GM-CSF in CHBT high, middle and low dose groups were increased significantly(P<0.05, P<0.01). Conclusion: The CHBT in given concentration could promote the production of EPO and GM-CSF after tumor chemotherapy and stimulate the hemocytogenesis to maintain the stability of peripheral haemogram, which may be the possible mechanism of CHBT ameliorating the haemogram of cancer after chemotherapy.国家自然科学青年基金项目(No.81202659);; 厦门市重大科技计划项目(No.3502Z20100006);; 福建省自然科学基金项目(No.2014J01373);; 厦门市科技计划项目(No.3502Z20153027)~

Analysis on the clinical experience of WANG Yan-hui in the treatment of tumor by syndrome differentiation based on Xiang thinking

王彦晖教授从事肿瘤中医治疗30余年,积累了丰富的临床诊疗经验。认为中医辨证论治思维的关键在于病机指导下的象症辨证。气滞、痰湿、瘀血等病理产物贯穿; 肿瘤病机的始终。病理产物必须除之而后快,而正气和脏腑的调理是祛邪的保障。病机的轻重缓急,应以象的变化为凭证。病机不变,象不变,临床上即应守方用药; 。王教授在临证中强调据象诊断、据象治疗、据象的变化反馈调整处方用药的中医诊疗思想颇具特色。Professor WANG Yan-hui has accumulated a wealth of clinical experience; in the treatment of tumor for more than 30 years. He thinks that the key; point of treatment based on syndrome differentiation is according to; Xiang thinking that under the guidance of pathogenesis. Qi stagnation,; phlegm-damp, static blood and other pathological products are always; complicated throughout the tumor pathogenesis. The pathological products; must be wiped out, while the regulation of vital qi and zang-fu viscera; is the insurance for eliminating pathogen. The order of priority of; pathogenesis should be according to the changes of Xiang. As the; pathogenesis and Xiang remains unchanged, the prescription of clinical; medication should be keeping the same. Professor WANG emphasizes that; diagnosis and treatment should be according to Xiang in the clinical.; The prescription adjustment by feeding back from the changes of Xiang is; a special characteristic of traditional Chinese medicine in diagnosis; and treatment.厦门市重大科技计划项目; 厦门市科技计划项

The Physiological Effects of Germanium Dioxide on the Germinating Rice Seeds

将水稻（OryzASATIVAl.）种子浸于从0到3Mg·l-1不同浓度梯度的gEO2溶液中，测量其生理指标：呼吸强度，可溶性糖含量，淀粉酶活性等。发现在浸种的前期，gEO2对以上各项生理指标均有促进作用，而随着浸种时间的延长，促进逐渐减弱并转为抑制，淀粉酶同功酶电泳则表明，植物体内复杂多样的同功酶系统在一定范围内对gEO2的毒害作用有某种程度的适应与调节能力Rice seeds were soaked in solutions with diffrent concentrations of GeO 2 ranged from 0 to 3.0 mg·L -1 .Respiratory intensity,quantity of soluble sugar and activity of amylase were tested during germination.It was shown that GeO 2 promoted all the indexes in the first stage of germination, but the promotive effect was decreasing late and at last GeO 2 became inhibitive.Isoenzyme of amylase was analyzed by PAGE.The results showed that the newly appeared isoenzyme of amylase in the germinating rice seed can releave the toxicity of GeO 2

人工气候箱在“六淫”研究中的应用

“六淫“的发生与气候密切相关,人工气候箱可以模拟出自然界可能出现的各种气候类型,为“六淫“实验研究的最重要手段之一,已在风、寒、湿、燥邪等研究中取得一定成果。然而由于气候对人体的影响规律尚不明确,所以研究中还存在同种邪气气候箱条件设置各异、动物在气候箱放置时间各异等问题,也是“六淫“研究今后要深入探讨的问题。认为随着人工气候箱的发展,可以模拟出更精确、复杂的气候环境,可望在“六淫“和其他气候相关科研中发挥更大作用。国家自然科学基金资助项目(81302876); 福建省自然科学基金资助项目(2013J05123

风险投资对上市公司投融资行为影响的实证研究

本文研究风险投资机构对上市公司投融资行为的影响机制和作用效果,结果发现:风险投资的加入不仅可以抑制公司对自由现金流的过度投资,而且可以增加公司的短期有息债务融资和外部权益融资,并在一定程度上缓解因现金流短缺所导致的投资不足问题。进一步研究还发现不同特征的风险投资机构均可起到抑制自由现金流过度投资的作用,但只有高持股比例、高声誉、联合投资或非国有背景的风险投资机构才能够显著地改善外部融资环境,缓解现金短缺公司的投资不足问题。综合本文研究结果,作者认为企业上市后仍然可以利用风险投资机构的监督职能、声誉资源和融资关系网络来解决代理问题和信息不对称问题,进而促进企业投融资行为的规范化和理性化