Different-source test image calibration method of image matching system

本发明涉及一种图像匹配系统的异源测试图像标定方法，包括以下步骤：建立可见光图像和红外图像序列的相似特征指标候选集合；利用灰色关联度分析方法度量异源图像候选集合中各个特征的相似性，并依此对相似特征指标集合进行关联程度排序，选取相似特征向量；根据基于Canny算子的边缘特征提取算法的阈值参数，选取不同参数，计算并划分特征值组合，形成标定测试试验方案；分别统计光电成像匹配系统对可见光图像和红外图像的匹配率，依据红外图像输出的匹配率结果进行分级，标定对应的可见光图像特征值范围。本发明保证在匹配系统工作在未知环境中，可以利用标定后的可见光图像完成匹配系统的测试与评估，保障图像匹配系统顺利完成任务。</p

Different-source test image calibration method of image matching system

本发明涉及一种图像匹配系统的异源测试图像标定方法，包括以下步骤：建立可见光图像和红外图像序列的相似特征指标候选集合；利用灰色关联度分析方法度量异源图像候选集合中各个特征的相似性，并依此对相似特征指标集合进行关联程度排序，选取相似特征向量；根据基于Canny算子的边缘特征提取算法的阈值参数，选取不同参数，计算并划分特征值组合，形成标定测试试验方案；分别统计光电成像匹配系统对可见光图像和红外图像的匹配率，依据红外图像输出的匹配率结果进行分级，标定对应的可见光图像特征值范围。本发明保证在匹配系统工作在未知环境中，可以利用标定后的可见光图像完成匹配系统的测试与评估，保障图像匹配系统顺利完成任务

多基因风险评分的构建及其在卒中领域的应用 Construction and Application of Polygenic Risk Score in Stroke

卒中是一种由遗传和环境因素共同作用引起的复杂疾病，人类遗传学的发展为卒中的个体化预防和治疗提供了新的机会。多基因风险评分是根据个体的基因型和相关的全基因组关联研究数据，对一种性状或疾病的遗传倾向进行估计，是遗传学研究中全基因组关联研究的补充方法。多基因风险评分可以对患者进行风险分层以进行个性化管理，从而有助于卒中等复杂疾病的精准预测和防控。基于此，本篇综述阐述了多基因风险评分的构建及其在卒中研究中的应用情况，以期为国内相关研究提供思路。 Abstract: Stroke is a complex disease caused by genetic and environmental factors. The development of human genetics had provided new opportunities for individualized prevention and treatment of stroke. Polygenic risk score (PRS) is an estimate of an individual's genetic liability to a trait or disease, calculated according to their genotype profile and relevant genome-wide association study (GWAS) data. PRS is a complementary method to GWAS in genetic research. PRS can stratify the risk of patients for personalized management, thus contributing to accurate prediction, prevention, and control of complex diseases such as stroke. Based on this, this review describes the development of PRS and its application in stroke research, aiming to provide insights for relevant domestic studies

一种用于观测液氧荧光光谱的样品池

本发明公开了一种用于观测液氧荧光光谱的样品池，包括液氧池、液氮池外胆及液氮池内胆，所述液氧池与液氮池的材质为派热克斯玻璃，并采用熔融一体的工艺制作。液氮池为内、外两层的保温装置，其内、外层之间为真空夹层。液氧池和液氮池两端为派热克斯玻璃材质的透明的激光通过窗，同时液氧池与液氮池侧壁中心处采用熔融一体的工艺焊接观察窗并用于收集荧光。本发明的优点在于解决了因液氮池与外界温差较大而在观察窗处结霜的问题，同时解决了液氧在室温下迅速挥发的问题

Pulmonary granulomas caused experimentally in mice by a recombinant trigger-factor protein of Propionibacterium acnes

Etiology of sarcoidosis remains unknown. A trigger factor from Propionibacterium acnes causes a cellular immune response in some sarcoid patients but not in nonsarcoid subjects. We examined whether experimentally induced hypersensitivity to the trigger factor gives rise to granulomas. Female C57BL/6 mice primed intravenously with P. acnes or not were sensitized with recombinant-protein RP35, a fragment of P. acnes trigger factor, and complete Freund\u27s adjuvant. In controls, RP35 was replaced with P. acnes or one of two control proteins. In primed and unprimed mice, pulmonary granulomas were found in some of the mice sensitized with RP35 or P. acnes but in no control-protein-sensitized mice. Detection of pulmonary granulomas (25-57%) did not differ significantly between mice sensitized with RP35 or P. acnes, primed or not. No difference in popliteal lymph-node-cell reactivity and serum antibodies to these two antigens was found between mice with and without pulmonary granulomas. P. acnes was cultured from the lungs of 8 (33%) of 24 untreated mice. The recombinant trigger-factor protein of P. acnes caused pulmonary granulomas in primed and unprimed mice sensitized with the protein and adjuvant. Sarcoid granulomas may form during hypersensitivity to antigens of P. acnes indigenous to the affected organ