Method of IC Layout Design and Examples

首先在理论上介绍了集成电路版图设计方法的详细步骤以及设计规则的特点。并结合一个运算放大器的版图设计实例详细讲解了集成电路版图设计的基本步骤技巧与准则。The theory and method of the layout design of integrated circuits were introduced So did the characters of the layout design rules By explaining the layout of an operational amplifier, the specific steps and principles of layout design were clearly illustrate

A Micro-Variable Capacitor Based on MEMS Technology

　通过对接触式电容压力传感器的改进,提出了一种基于MEMS技术的微变电容模型。为确定外加驱动电压与由此所引起的电容变化之间的非线性关系,提出了一种有效的基于有限元的方法,并设计了相应的加工工艺流程,说明了其工艺的可实现性。With the improvement of the touchmode capacitive pressuresensor,a microvariable capacitor based on MEMS technology is presented In order to define the nonlinear relationship between the applied driving voltage and the capacitance variation, an effective method based on finite element analysis (FEA)is proposed Processing steps are designed, and the feasibility of the process is elaborate

Design of a micro capacitive acceleration sensor based on MEMS

给出了一种基于MEMS技术制作的微电容式加速度传感器的结构及工艺。为了准确地把握这种微电容式加速度传感器的力学和电学特性,仔细地建立了它的力学模型。在此基础上,详细分析了它的动态特性———模态。并用有限元的方法分析和计算了微电容式加速度传感器的加速度与电容信号的非线性输入输出关系,并结合实测参数验证了模型的有效性。最后提出了一种详细的有效的基于MEMS技术的微电容式加速度传感器的结构以及加工工艺流程。基于MEMS技术制作的微电容式加速度传感器具有结构简单、工作可靠和工作范围大的特点。根据这套方法,可以比较方便地设计并加工不同测量要求的加速度计。Structure and process of a micro capacitive acceleration sensor based on MEMS technology were given.So did the fabrication process.With the purpose of grasping the sensor's characters of mechanics and electrics,its mechanics model was discussed.On this basis the sensor's modal analysis was made.In order to get the nonlinear relationship between the acceleration and capacitive signal,an effective method based on FEA was proposed.The detail processing steps was designed,which explained the feasibility of the fabrication.The sensor has advantages of simple structure,operation reliability and the wide work range.Using this set of method,sensors with different test ranges can be designed and fabricated

Relationship between Disaster Prevention Awareness and Personality Traits of Japanese Elementary School Students

本研究の目的は小学生の性格特性と防災意識との関連を明らかにすることである。対象者はA県内小学校5・6年生であった。調査内容は性格特性として小学生用5因子性格検査40項目と防災意識の質問10項目であった。その結果5・6年生124名の調査協力が得られ未回答者を除外した117名を分析対象とした。児童の性格特性は協調性と統制性の2項目が基準の平均値よりも得点が高く他者への思いやりや責任感が強い集団であった。児童の防災意識は「自然災害は怖いと思いますか？」等の得点が高かった。また統制性は防災意識10項目のうち9項目で有意な正の相関関係と重回帰分析の結果、防災意識7項目の影響要因であった。統制性は性格特性5因子の中で最も防災意識に影響を与える特性であることが示された。今後は個人の強みを活用しながら より広範な防災に対する風土を醸成することが重要である。This study aims to clarify the relationship between elementary school students’ personality traits and disaster prevention awareness. The participants were fifth-and sixth-graders at an elementary school. The content of evaluation consisted of 40 items of a 5-factor personality test for elementary school students as personality traits, and 10 questions on disaster prevention awareness. In all, 124 fifth- and sixth-grade students participated in the survey, and after excluding non-respondents, 117 students were included in the analysis. Regarding the children’s personality traits, their scores on the two items of agreeableness and controllability were higher than the standard average values, indicating that the children had a strong sense of concern and responsibility for others. Regarding children’s disaster prevention awareness, the scores for such items as “Do you think natural disasters are scary?” were high. In addition, controllability showed a significant positive correlation with 9 of the 10 disaster prevention awareness items, and multiple regression analysis showed that it was an influencing factor for 7 disaster prevention awareness items. Controllability was shown to be the personality trait that most influenced disaster prevention awareness. In the future, it will be important to foster a broader culture of disaster prevention while leveraging individual strengths.departmental bulletin pape

IC Design and Test of a High Performance Operational Amplifier Applied in Certain MEMS Devices

根据特定电容式微传感器后续处理电路的高性能要求,设计一个运算放大器芯片。设计中采用了美国MOSIS公司提供的n阱0.35μm cmos工艺的SPICE BSIM3 mos管模型,手算估计芯片的参数,然后采用了两种能系统反映芯片特性的测量电路对设计进行了性能测量,并根据测试结果对设计做出相应调整。从最终测试结果来看,设计的运算放大器具有很好的静态和动态性能。According to the specific performance objectives required by certain micro capacitive sensors, a high performance OpAmp was designed. Using the SPICEBSIM 3 model parameters for the 0. 35 fim, n -Well CMOS process provided by the MOSIS service, the hand calculations to estimate device sizes and bias currents were firstly made. Two test circuits used to test the systemic function of the OpAmp help adjust the initial design. The finial test results indicate the high performance of the OpAmp

牛樟芝寡糖的制备分离及其生物活性的研究

目的牛樟芝(Antrodia camphorata,Antrodia cinnamonea)为台湾特有珍贵药用真菌品种,据报道,牛樟芝含有多种生物活性多糖,具有抑制肿瘤细胞的增生、抑制内皮细胞血管新生、提高免疫力以及抗氧化等作用。与多糖相比,寡糖因其水溶性好、易被机体吸收利用等特点,近年来倍受关注,但牛樟芝寡糖的结构及其生物学活性讫今尚没有相关报道。本研究旨在建立牛樟芝寡糖的制备分离与质谱鉴定方法,同时对其生物活性组分进行初步评价。方法采用酸水解方法制备牛樟芝寡糖样品;采用TLC/HPLC/MALDI-TOF-MS分析方法对牛樟芝寡糖进行初步结构鉴定;对牛樟芝寡糖进行生物活性评价,包括体外抗氧化实验、细胞实验。结果对酸解牛樟芝寡糖样品进行初步结构鉴定发现水解产物主要为聚合度6-12的寡糖;体外抗氧化活性实验结果表明牛樟芝寡糖具有良好的抗氧化活性;细胞活性实验结果表明,牛樟芝寡糖对细胞没有损伤,能够促进细胞的增殖,具有明显的抗炎活性

化学酶法生产可控聚合度及脱乙酰度壳寡糖方法初探

壳寡糖具有抗炎、抗肿瘤及免疫调节等一系列生物活性。研究显示,壳寡糖的聚合度及脱乙酰度在其生物活性发挥过程中起到关键作用:较高聚合度(>5)及特定脱乙酰度壳寡糖具有更高的生物活性。目前,商品化的壳寡糖是以较高脱乙酰度(>90%)的壳聚糖为原料经酶法水解获得,产物中较低聚合度(<5)壳寡糖所占比例较大,影响其生物活性。本研究旨在探索一条可控聚合度及脱乙酰度壳寡糖的生产方法。在对甲壳素进行预处理的基础上,使用高浓度NaOH对其脱乙酰,实现了在较低温度(60℃)下较为均相的快速(<4h)脱乙酰反应,产物可完全溶解于1%乙酸。在此基础上,利用壳聚糖水解酶类对弱酸溶解的均相脱乙酰甲壳素进行全水解。MALDI-TOF质谱检测结果显示,经过1h均相脱乙酰的甲壳素酶解后的产物为脱乙酰度较低,聚合度主要集中在5-13的壳寡糖(图1)。通过脱乙酰时间及水解酶类的选择,我们可以初步实现壳寡糖聚合度及脱乙酰度的控制,这为不同聚合度及脱乙酰度壳寡糖生物活性的研究及其应用奠定良好基础

岩藻寡糖的制备及抗氧化活性测定

目的岩藻多糖多存在于褐藻以及海洋无脊椎动物中,是一种独特的结合有硫酸基团的水溶性多糖,由硫酸基岩藻糖、半乳糖、葡萄糖、木糖、鼠李糖、糖醛酸等单糖组成。研究发现岩藻多糖具有抗癌、增强免疫、抗炎、抑制神经细胞损伤、抗病毒等多种生物活性。与多糖相比,寡糖因水溶性好、易被机体吸收利用等诸多独特的功能,近年来更受人关注,但岩藻寡糖的生物学活性讫今尚没有相关报道。本研究旨在建立岩藻寡糖的制备方法,同时对其功能活性进行初步评价。方法采用毛细管电泳法测定岩藻多糖的单糖组成;用酸水解方法制备岩藻寡糖样品;对岩藻寡糖进行抗氧化活性评价,包括羟自由基清除实验、DPPH自由基清除实验、超氧自由基清除实验、还原活性实验与NO清除实验。结果通过毛细管电泳法确定岩藻多糖主要由Xyl:Glc:Rha:Fuc:Gal:Man:GlcA:GalA(ManA)组成,其摩尔比为1.10:1.00:0.60:15.41:9.56:4.78:5.13:2.13(1.51);对酸解寡糖样品进行质谱检测发现水解产物主要为2-8糖;体外抗氧活性实验结果表明,岩藻寡糖具有良好的自由基清除能力