Design and Implementation of Textile and Garment Enterprises ERP System

本文以新疆某纺织服装企业ERP项目的构建和部署为背景，参考现有的成熟ERP系统框架，对企业的ERP项目的实施过程进行了分析、设计与实现。论文重点阐述了在整个ERP系统实施过程中，将用户的需求与企业实际业务流程和管理结合起来，将企业业务流程管理与ERP理论融为一体，建立基于纺织服装企业样品、采购、仓储、生产、财务、行政的管理平台，解决了该企业业务流程管理混乱、数据处理低效繁琐、产品信息缺失等问题。 本文首先采用面向对象方法对企业业务流程、功能需求进行了详细分析和阐述，为软件系统开发和后期扩展建设提供有价值的依据。在此基础上，基于SSH框架和分层思想，对系统总体架构进行了设计，并优化了企业业务流...The dissertation uses build and deploy of ERP project of a textile and garment enterprise in Xinjiang as the background, eferring to the existing mature ERP system framework, to analysis this enterprise’s ERP project implementation process. Furthermore,to design and implementation of enterprise ERP software system. The dissertation describes the user’s requirements and the actual business manageme...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201323144

Study of (Asymmetric) A3 Coupling Reactions Catalyzed by A Dicopper Complex CuI2(pip)2 and Chiral Copper Complex

炔丙基胺类化合物是十分重要的有机合成中间体，在含氮化合物、天然产物的合成中具有非常广泛的用途，而许多含有手性炔丙基胺结构的化合物则具有重要的生理活性，是药物分子合成的关键砌块。本论文的目的是探索研究炔丙基胺类化合物的高效合成方法，主要包括以下两部分： 第一部分双核铜络合物CuI2(pip)2催化的醛-炔-胺(A3)偶联反应 近年来，非手性炔丙基胺类化合物的合成已经取得了重大的研究进展，尤以醛-炔-胺A3偶联反应的研究成果最为显著，且已发展形成了多种优秀的催化体系，然而这些合成方法中依然存在着许多问题与挑战。因此，深入研究A3偶联反应，发展更高效、普适的反应体系来合成炔丙基胺类化合物仍具有十...Propargylamines are versatile building blocks for the synthesis of nitrogen-containing heterocyclic compounds and natural products. Furthermore, some chiral propargylamines are important intermediates for the preparation of pharmaceutical agents. The present thesis aims to develop a highly efficient synthetic method to propargylamine, which contains two sections: Section one Aldehyd...学位：理学硕士院系专业：化学化工学院_物理化学学号：2052013115165

Study on the effects of retinoic acid on the configurational changes and alteration of nuclear matrix proteins in human osteosarcoma cell line MG-63

本文在鉴定维甲酸（retinoicacid，RA）诱导人成骨肉瘤MG-63细胞终末分化的基础上，应用选择性抽提、整装透射电镜和蛋白质组学分析技术，对MG-63细胞诱导分化过程中核基质-中间纤维系统的构型变化和核基质蛋白组成的变化进行系统研究。分析鉴定与肿瘤增殖分化相关的特异核基质蛋白，并探索它们在肿瘤细胞诱导分化过程中的调控作用，以期能够在较为整体的水平上进一步认识细胞癌变与逆转机理，从而找出细胞增殖与分化调控研究的新方向。实验结果显示，经1μmol/LRA处理之后，人成骨肉瘤MG-63细胞的增殖受到了明显抑制，发生了G0/G1期阻滞，细胞形态改变的同时伴随着癌基因c-myc、c-fos的表达...In this study, the Retinoic Acid (RA) was used to induce the human osteosarcoma MG-63 cells into differention and its effects were investigated by selective extraction-whole mount optic and transmission electron microscopy and techniques of proteomic. The differentially expressed nuclear matrix proteins were analyzed in order to explore the molecular mechanisms in a system level. The results re...学位：理学硕士院系专业：生命科学学院生物医学科学系_细胞生物学学号：20032608

A Study on Determinants of Investment Return of Private Placements in the Primary Market

近年来，我国定向增发发展势猛，不仅成为上市公司广泛采用的股权再融资方式，也成为广大投资者日益青睐的投资热点。而投资者除了可以利用公告效应在二级市场买卖股票进行套利之外，还可以直接在一级市场参与定向增发股份认购。但以往针对定向增发投资价值的研究主要是从二级市场投资者的角度出发，探讨定向增发的短期公告效应和长期股价反应，本文则站在一级市场投资者的视角，对定向增发解禁时的投资回报问题进行了探讨，试图为一级市场投资者的认购决策提供一定的意见，也为企业如何通过定向增发来实现股权价值最大化提供一定的思路。 本文利用2006~2013年之间进行定向增发并已解禁的上市公司为样本，从定向增发特点、发行公司特点...In recent years, the private placement has developed rapidly, which has become not only the most important refinancing way among listed companies but also a popular investment choice in capital market. While the previous studies on the investment value of private placement were mainly from the perspective of investors in secondary market to discuss the announcement effect and long-term stock price...学位：管理学硕士院系专业：管理学院_会计学学号：1752012115112

Effects of Retinoic Acid on Proliferation and Associated Gene Expression of Human Osteosarcoma MG-63 Cells

目的:研究维甲酸对人成骨肉瘤Mg-63细胞增殖和相关基因表达的影响,以探索其对成骨肉瘤细胞的生物学效应。方法:以1μMOl/l维甲酸处理人成骨肉瘤Mg-63细胞,生长曲线测定,流式细胞仪分析、光镜观察和免疫细胞化学检测等研究维甲酸对Mg-63细胞的生长曲线、细胞周期和相关癌基因、抑癌基因表达的影响,并对其作用机理进行初步分析。结果:维甲酸处理7天后,Mg-63细胞生长抑制率达到42.2%,g0/g1期比例达到61.8%,细胞形态铺展,排列趋于规则,癌基因C-MyC、C-fOS的表达降低,而抑癌基因rb、P27表达上调。结论:1μMOl/l维甲酸可以有效抑制细胞的增殖活动,改变细胞恶性形态特征,下调癌基因C-MyC、C-fOS和上调抑癌基因rb、P27的表达,从而对人成骨肉瘤细胞分化具有诱导作用。Objective:To explore effect of Retinoic Acid(RA) on proliferation of human osteosarcoma MG-63 cells and its mech-anism of antitumor.Methods:The MG-63 cells treated by 1μmol/L RA were subjected to growth curve counts,flow sytometry,im-muncocytochemical assay and light microscopy.We investigated the influence of RA on proliferation,cell cycle,expression of associated oncogene and tumor suppressor gene of MG-63 cells.Then we analyzed the mechanism of RA in inducing differentiation primarily.Re-sults:Seven days after treated by 1 μmol/L RA,the inhibition rate of proliferation of MG-63 cells amounted to 42.2 % and RA reduced the rate of progression from G1 to S phase.The cells tend to be flat and spread.Meanwhile,the expression level of oncogene was down-regulated and the expression level of tumor suppressor gene was upregulated.Conclusions:1μmol/L RA could inhibit proliferation of MG-63 cells,reverse the malignant phenotype characters,downregulate expression of Oncogene c-Myc,c-fos and upregulate expression of Tumor Suppressor Gene Rb,p27,as a result,induce MG-63 cells into differentiation effectively.国家自然科学基金资助项目(30470877

Response of Photosynthetic Apparatus to Different Irradiance in Flag Leaves of High-Yielding Winter Wheat PH01-35 Grown under Low Light Conditions

为了解弱光下生长的小麦叶片在不同光强下PS II和光合电子传递链的工作状态,解释其突然转入强光下时发生光抑制和光破坏的原因,以PH01-35为材料,采用大田人工遮光的方法,测定了小麦旗叶叶绿素含量、光合特性参数及快速光曲线。弱光处理15 d后,旗叶叶绿素含量明显上升,净光合速率、光补偿点、光饱和点、表观量子效率、羧化效率均出现不同程度的下降。与250μMOl M-2 S-1的弱光适应3 H相比,1 200μMOl M-2 S-1的强光适应3 H后,弱光下生长叶片的快速光曲线初始斜率下降幅度较大,曲线下降部分的斜率、最大相对电子传递速率、半饱和光强的上升幅度均小于自然光下生长的叶片,光能利用能力较低,其非光化学猝灭系数nPQ也明显低于自然光下生长的叶片,为自然光下生长叶片的87.5%。弱光下生长的小麦叶片光能吸收能力增强,但较低的光能利用能力和过剩光能耗散能力是其转入自然强光后易发生光抑制甚至光破坏的主要原因。To further explain the mechanism of photoinhibition and light damage in wheat(Triticum aestivum L.) leaves when it was suddenly transferred from low light to high light conditions,the responses of photosynthetic apparatus in shaded leaves of the high-yielding winter wheat line,PH01-35,were examined using chlorophyll fluorescence and gas exchange techniques.After 15-day shading,the chlorophyll content increased greatly,but the net photosynthetic rate(Pn),light compensation point(LCP),light saturation point(LSP),apparent quantum yield(AQY),and carboxylation efficiency(CE) all decreased.Compared with leaves grown in full sunlight,the initial slope(α),decline slope(β),maximum relative electron transport rate(rETRmax),and minimum saturating irradiance(Ek) of rapid light curves in leaves grown in low light were lower when the plant was transferred from low light intensity of 250 μmol m-2 s-1 to high light intensity of 1 200 μmol m-2 s-1.Non photochemical quenching(NPQ) in leaves grown in low light was significantly lower than that in leaves grown in full sunlight,indicating that the ability of light use and thermal energy dissipation was limited in leaves grown in low light.The wheat leaves grown in low light were more suscepti-ble to photoinhibition due to low CO2 assimilation and photoprotective ability,such as xanthophylls cycle-dependent dissipation of excessive energy,despite the better energy absorbability in low light conditions.山东省农业良种工程重大课题(鲁农良种字[2006]6号)资

轮状病毒VP4~*高聚体的制备及其免疫保护性评价

在前期工作中发现,截短的轮状病毒VP4~*蛋白(aa26–476)在大肠杆菌中能够以可溶形式表达,且在小鼠模型中具有较高的免疫原性和免疫保护性。本研究通过颗粒化进一步提高VP4~*蛋白的免疫保护性。通过37℃水浴加热处理24h使VP4~*蛋白多聚化,通过高效液相色谱、透射电镜、分析超离等分析VP4~*蛋白颗粒化程度,通过酶联免疫吸附试验分析颗粒化对VP4~*蛋白与中和抗体反应性的影响;通过差示量热法分析VP4~*高聚体的热稳定性;最后,通过小鼠母传抗体模型研究颗粒化对VP4~*免疫原性和免疫保护性的影响。结果表明,VP4~*蛋白高聚体结构均一,并且相比三聚体,具有更高热稳定性和中和抗体结合活性;在内毒素<20 EU/mg的条件下,与铝佐剂混合,刺激小鼠产生更高滴度的中和抗体;对轮状病毒导致的腹泻具有更高的免疫保护性。综上所述,VP4~*高聚体的研究为轮状病毒基因工程亚单位疫苗的研制提供了更广阔的思路。国家自然科学基金(No.81501741);;福建省科学技术创新平台(No.2014Y2004)资助~

Dynamic Evolution of Regional Ecological Services Based on TM Remote Sensing

针对传统评估区域生态系统服务价值空间异质性的问题,本研究将TM遥感影像与价值评估法相结合,测算出针对研究区域的当量因子表,并建立了只需遥感影像数据即可快速并较为精准地动态计算区域生态系统服务价值的多元回归模型。文章以北京市永定河、厦门市和青海省不同尺度为例,对该方法评估区域生态系统服务价值的可行性和准确性进行了讨论,以期为生态综合管理提供定量化参考依据。This paper discussed the dynamic evaluating of regional ecological services with remote sensing technique,based on the comprehensive analysis the character of indexes method and currently equivalent method applying to regional ecological services.With the established method in the literature,it discussed the practical possibility for evaluation the temporal and special regional ecological services in Yongding River,Xiamen and Qinghai province.Compared with the traditional static indexes evaluation,our method discussed the possibility of dynamically evolutional evaluation,in order to provide reference of ecosystem management.北京市科学技术委员会“永定河生态修复目标体系研究”(D090409004009003);北京市生态学重点学科项

Study on the Isolation Identification and Antitumor Activity of a Phenol Derivative from Mangrove Fungus BYY-1

[作者简介] 杜希萍( 1978—) ，女，讲师，从事天然产物化学方面的研究． 通讯作者: 苏文金( 1956—) ，男，教授，从事海洋药物与食品方向研究，E-mail: wjsu@ jmu. edu. cn．[中文文摘]采用硅胶柱层析、薄层层析、Sephadex LH-20柱层析从红树内生真菌BYY-1的次级代谢产物中分离到化合物B1.通过乙酰化、NMR、HR ESI-Q-TOF MS等技术鉴定了化合物B1的结构,确定其为首次从红树内生真菌中分离到的化合物.运用MTT法和流式细胞术研究了化合物B1的抗肿瘤活性,结果表明,化合物B1可显著抑制Hela细胞的增殖[英文文摘]Compound B1 was obtained from the secondary metabolites of mangrove fungus BYY －1 using silica gel column chromatography，thin layer chromatography and Sephadex LH － 20 column chromatography．The structure of compound B1 was elucidated by acetylation，NMR and HR ESI －Q －TOF MS analysis，and compound B1 was isolated from mangrove fungi for the first time． The antitumor activity of compound B1 was studied by the methods of MTT and flow cytometric DNA analysis． The results showed compound B1 could significantly inhibit the proliferation of Hela cells with IC50 3. 3 μg /mL，and induce evident Hela cells apoptosis when compound B1 was 4 μg /mL．中央高校基本业务费资助项目(2010121092); 福建省科技计划重点项目(2011N1008);; 集美大学博士启动基金资助项目(ZQ2011004

长汀县赢坪史前遗址发掘简报

2012年福建博物院对赢坪两处遗址进行了抢救性考古发掘,获得了一批包括石器、陶器、铜器、石范等内涵丰富的文化遗物,这批遗物可进一步了解闽西地区的史前文化发展序列及文化面貌,并且对于多地区文化间的交流研究也有一定的作用