4 research outputs found

    中老年HIV/AIDS患者合并慢性非传染性疾病情况与生命质量的关联研究

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    目的了解中老年HIV/AIDS患者合并慢性非传染性疾病(简称慢性病)的患病率及与生命质量的关联。方法采用横断面研究调查广州医科大学附属市八医院感染科门诊432名45岁及以上HIV/AIDS患者,经质量控制366名研究对象纳入分析。采用自制问卷和欧洲5维健康量表(EQ-5D-3L)调查慢性病和生命质量,采用Tobit回归分析慢性病与生命质量的关联。结果366名研究对象纳入分析,合并心血管疾病29人(7.9%),高血压45人(12.3%),高血糖122人(33.3%),高脂血症151人(41.3%),癌症7人(1.9%),慢性肾脏疾病17人(4.6%),慢性肝脏疾病38人(10.4%),肌肉骨骼疾病21人(5.7%),合并至少一类慢性病253人(69.1%)。EQ-5D效用指数的中位数(上下四分位数)为1.000(0.964~1.000)。多因素Tobit回归结果显示,合并癌症[ba=-0.08, 95%CI(-0.15, -0.01), P=0.036]、慢性肾脏疾病[ba=-0.07, 95%CI(-0.12, -0.02), P=0.006]、肌肉骨骼疾病[ba=-0.09, 95%CI(-0.13, -0.05), P<0.001]和≥3类慢性病[ba=-0.05, 95%CI(-0.08, -0.01), P=0.013]均与EQ-5D效用指数呈负向关联。不同CD4+T细胞水平分层分析结果显示,CD4≤500个/μL组合并高血压[ba=-0.07, 95%CI(-0.12, -0.02), P=0.007]、慢性肾脏疾病[ba=-0.10, 95%CI(-0.18, -0.03), P=0.006]、肌肉骨骼疾病[ba=-0.15, 95%CI(-0.22, -0.07), P<0.001]和≥3类慢性病[ba=-0.09, 95%CI(-0.09, -0.01), P<0.001]与EQ-5D效用指数呈负向关联,CD4>500个/μL组合并癌症[ba=-0.11, 95%CI(-0.20, -0.01), P=0.031]与EQ-5D效用指数呈负向关联。结论中老年HIV/AIDS患者合并慢性非传染性疾病比例较高,合并癌症、慢性肾脏疾病等慢性病及慢性病类数与生命质量呈负向关联,但这种关联在不同CD4水平HIV/AIDS患者中存在差异,建议对HIV/AIDS患者的慢性病进行预防和早期识别,并加强艾滋病与慢性病卫生服务的联系与整合,对艾滋病和慢性病进行共同管理和控制,以提高目标人群的生命质量

    Amplitude analysis of the decays D0π+ππ+πD^0\rightarrow\pi^+\pi^-\pi^+\pi^- and D0π+ππ0π0D^0\rightarrow\pi^+\pi^-\pi^0\pi0

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    Measurement of integrated luminosity of data collected at 3.773 GeV by BESIII from 2021 to 2024*

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    Determination of the number of ψ(3686) events taken at BESIII

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    The number of ψ(3686) events collected by the BESIII detector during the 2021 run period is determined to be (2259.3±11.1)×106 by counting inclusive ψ(3686) hadronic events. The uncertainty is systematic and the statistical uncertainty is negligible. Meanwhile, the numbers of ψ(3686) events collected during the 2009 and 2012 run periods are updated to be (107.7±0.6)×106 and (345.4±2.6)×106, respectively. Both numbers are consistent with the previous measurements within one standard deviation. The total number of ψ(3686) events in the three data samples is (2712.4±14.3)×10^
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