8 research outputs found

    실물옵션을 이용한 대형연구개발사업의 경제적 타당성 평가 방법론

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    학위논문(석사)--서울대학교 대학원 :협동과정 기술정책전공,2003.Maste

    췌장신경내분비종양에서의 병리학적 등급과 전산화 단층촬영 조영 증강 정도의 연관성

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    학위논문 (석사)-- 서울대학교 대학원 : 의학과, 2017. 2. 류지곤.Background/Aims: Pancreatic neuroendocrine tumors (PNETs) are rare diseases but gradually increasing in prevalence with different prognosis. Neuroendocrine tumors are classified into low-grade (G1), intermediate grade (G2), and high-grade (G3, neuroendocrine carcinoma) by WHO 2010 grading system. Prognostic validity of WHO grading system has been established by several studies. Multiphase contrast-enhanced computed tomography (CT) is known as the most useful imaging modality for the diagnosis of pancreatic tumors. We aimed to investigate whether CT enhancement pattern is associated with the pathologic tumor grades according to WHO classification and can predict those of pancreatic neuroendocrine tumor. Methods: Between January 2011 and December 2015, Ninety patients who underwent multi-phase contrast-enhanced CT and were diagnosed as pancreatic NETs histopathologically were retrospectively reviewed. The diagnosis of a PNETs were established by histopathological examination and immunohistochemistry on tissue samples, based on the 2010 WHO classification. Results: Ninety pancreatic NETs included sixty-two G1 (68.9%), twenty-one G2 (23.3%), seven G3 (7.8%). The enhancement values of the early arterial phase were significantly different among three groups (G1 vs. G2p=0.043, G1 vs. G3p=0.001, G2 vs. G3p=0.027). In the late arterial phase, there was a difference between grade 1 and grade 3, grade 2 and 3, but no significant difference between grade 1 and grade 2 (G1 vs. G2p=0.804, G1 vs. G3p=0.016, G2 vs. G3p=0. 0.022). The enhancement value of the portal phase did not differ significantly between the three groups. In G1 and G2, mean CT attenuation values highly increased in arterial phases and after which declined in portal phase. Enhancement values of G3 tumors showed no statistical difference between late arterial and portal phases. ROC analysis of the early arterial enhancement value for the differentiation of the grade 1 tumors was comparable to the tumor size. Conclusion: CT enhancement value of early arterial phase and degree of change among arterial phases can be help for the differentiation of pathologic grade of pancreatic neuroendocrine tumorsIntroduction 1 Methods 3 Results 6 Discussion 22 References 28 Abstract in Korean 31Maste

    폴리이미드의 구조-성질 관련성 : 분자 시물레이션 접근

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    Thesis (master`s)--서울대학교 대학원 :섬유고분자공학과,1997.Maste

    Setting the Evaluation standards and Evaluation of ‘dramatic ability’ in Drama Education

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    A study on erlang loss system with multi-type customers

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    학위논문(석사) - 한국과학기술원 : 산업및시스템공학과, 2013.2, [ iv, 25 p. ]본 학위 논문에서는 두 종류 이상의 고객이 도착하는 얼랑 손실 시스템에 대한 연구를 시행하였다. 이 연구를 통해 가역성을 전제로 하지 않는 상태의 시스템에서 정상 상태 확률을 구할 수 있었고, 이를 통해 시스템을 컨트롤 할 수 있는 변수로서의 서버 대응 확률을 찾았다. 또한 구한 확률 값을 이용하여 시스템의 단위 시간당 일 처리량인 작업처리율을 이용해 시스템을 최적화 할 수 있는 확률을 찾아 수치예제를 통해 분석하였다. 본 연구결과가 가존의 연구결과에 비교하여 의미를 갖는 점은 시스템을 최적화 하는데 필요한 대응확률을 구하고 이를 이용하여 작업처리율을 통해 실제 사례에서도 적용가능 하다는 것을 확인한 것이다. 추후 연구 과제로는 도착하는 고객의 종류가 세 종류가 되는 경우의 시스템을 분석하여 점진적으로 일반적인 경우까지 분석해 나가는 것이다.한국과학기술원 : 산업및시스템공학과
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