10 research outputs found
일개 대학병원 건강증진센터 방문 수진자들을 대상으로 한 C reactive protein, 백혈구와 2형 당뇨와의 상관관계
학위논문(석사)--서울대학교 보건대학원 :보건학과 보건학전공,2004.Maste
Related factors of metabolic syndrome and their gender difference in Korea
학위논문(박사) --서울대학교 대학원 :의학과 가정의학 전공,2007.Docto
Influences of electrophoresis of charged droplet on cells in dielectric fluid
MasterIn this research, when method of electrophoresis of charged droplet (ECD) was used for cell manipulation, safety of that method on living cells and availability was studied. ECD one of method for droplet actuation charge up droplet first, then using electric field make droplet moving in dielectric fluid. This mechanism needs high electricity for electric field and silicone oil for dielectric fluid. Electricity higher than 1000 V seem to enough dangerous to living cells and silicone oil. For resolving this concern, influences of electricity on cells in electric field range of 1 ~ 3 kV/cm was examined, and there is almost no influences. It could be explained by faraday`s cage theory. Silicone oil is not harmful to living cells, too. As the final outcome, method of electrophoresis of charged droplet is safe to cells and can be good method on field of biological application
펄스 레이저를 이용한 금속 나노 소재 소결 공정 개발
DoctorWith ever-increasing demand for flexible, high-resolution, lightweight, and miniaturized electronic devices, development of pulsed-laser sintering processes in micro/nanoscale has recently attracted substantial attention. In the sintering process, such metallic nanomaterials as metal nanoparticles (NPs) and nanowires (NWs) are widely employed owing to their unique characteristics. For example, as the size of a material is reduced to nanoscale, the melting/sintering temperature is remarkably lowered by the thermodynamic size effect. Accordingly, a number of laser sintering processes have been developed using various lasers. In laser sintering, CW (continuous-wave) lasers or pulsed lasers with a pulse width longer than nanoseconds have typically been employed.
In this work, we analyzed and developed micro-/nanoscale metal sintering processes using femtosecond and nanosecond pulsed-lasers. In the first part, an ultrafast laser sintering process was developed using a femtosecond laser with a pulse width of 50 fs. In the study, the physical mechanisms and characteristics of femtosecond laser sintering of silver nanoparticles (Ag NPs) were analyzed and compared with those of nanosecond laser sintering. In the second part, a novel non-thermal, i.e., mechanical, sintering process using pulsed laser-induced shockwave was developed for potential application of the technology to highly heat-sensitive substrates. Finally, for various substrates, optimized sintering strategies were proposed to enhance the properties of sintered film.
Fabrication of thin-film electrodes/patterns on various substrates, including polymer, silicon, glass, and metal substrates, by femtosecond laser irradiation was demonstrated, resulting in significantly better properties of sintered film than those obtained by nanosecond laser sintering. Femtosecond laser sintering occurred by solid-state atomic diffusion at low fluences and by liquid-state recrystallization, i.e., full-melting, at high fluences. Pulsed laser-induced shock pressing could sinter Ag NPs mechanically without severe thermal damages. Furthermore, the laser shock pressing method produced Ag films with substantially improved film properties, e.g., low surface roughness, reduced crack generation, increased adhesion strength, and low porosity. Comprehensive parametric studies were performed to optimize the femtosecond laser sintering process. For a given particle-substrate combination, matching the coefficient of thermal expansion was key to producing mechanically, and thus electrically, robust thin films
Autonomic Service Composition of Localized Ubiquitous Service for Open Service Gateway
학위논문(석사)--아주대학교 대학원 :전자공학과,2005무선 네트워크 기술과 모바일 컴퓨팅 기술의 발전과 함께 웹 서비스 기술이 발전되어, 유비쿼터스 컴퓨팅, 유비쿼터스 네트워크와 같은 새로운 패러다임을 탄생시켰다. 유비쿼터스 기술들을 기반으로 다양한 종류의 유비쿼터스 서비스들이 개발되고 제공될 것이다. 이러한 서비스들은 홈, 사무실, 공항, 전시장 등과 같은 위치 환경과 깊은 관계를 맺고 위치환경에 따라 차별된다. 지역화된 유비쿼터스 서비스들이 사용자가 깨닫지 못하는 사이에 사용자에게 제공되어지기 위해서, 사용자의 환경정보에 따라서 다양한 지역서비스를 사용하는데 필요한 프로그램들을 사용자의 기기에 동적으로 전달해주고, 지역에 따라 분산된 다양한 서비스들을 효과적으로 관리해 주는 시스템이 필요하다. 본 논문에서 이러한 시스템을 자동 서비스 구성 시스템(ASCS: Autonomic Service Composition System)이라 정의하고, 자동 서비스 구성 시스템을 제안하였다. 자동 서비스 구성시스템은 사용자가 서비스 지역에 들어오면 지역 환경정보를 사용자에게 제공하고 자동으로 사용자가 선택한 지역 서비스 프로그램을 다운받아 설치하여 사용할 수 있게 하여주고 분산된 지역 서비스들을 통합적으로 관리할 수 있게 한다. 이러한 자동 서비스 구성 시스템은 리모트 매니저, 서비스 게이트웨이, 모바일 디바이스로 구성되어 있다. 또한 본 시스템을 802.11b, Bluetooth, OSGi프레임 워크를 기반으로 구현하였다.목차
목차 = ⅰ
약어표 = ⅲ
그림목차 = ⅳ
국문요약 = ⅴ
제 1 장 서론 = 1
제 2 장 ASC 시스템 구성요소 = 4
제 1 절 환경인지 = 4
제 2 절 자동 서비스 구성 시스템 = 6
1. 리모트 매니저 = 7
2. 서비스 게이트웨이 = 8
3. 모바일 기기 = 9
제 3 절 모바일 코드 = 11
제 4 절 유비쿼터스 지역 서비스 = 12
제 3 장 ASC 시스템 구조와 플로우 = 14
제 1 절 ASC 시스템 구조 = 14
1. 원격 서비스 게이트웨이 관리 서비스 = 15
2. 환경인지 자동 서비스 구성 서비스 = 16
3. 위치 인지 서비스 = 18
제 2 절 ASC 시스템 플로우 = 19
제 3 절 ASC 시스템 구현 = 23
제 4 장 성능 평가 및 시나리오 = 26
제 1 절 성능 평가 = 26
제 2 절 구현된 시나리오들 = 30
제 5 장 결론 = 32
Acknowledgement = 33
참고 문헌 = 34
Abstract = 35|그림 목차
그림 1. 자동 서비스 구성(ASC) 시스템 구성도 = 6
그림 2. 자동 서비스 구성(ASC) 시스템 구조도 = 14
그림 3. 자동 서비스 구성(ASC) 시스템 플로우 = 19
그림 4. 서비스 게이트웨이와 모바일 기기의 구조도 = 23
그림 5. 자동 서비스 구성(ASC) 시스템의 성능평가 결과 = 28
그림 6. Hanging 시스템과 ASC 시스템의 세부 성능평가 비교 = 29
그림 7. Hanging 시스템과 ASC 시스템의 서비스 구성시간 비교 = 29MasterAs web service technology evolves with advances in wireless network technologies and mobile computing devices, many types of services provided through a ubiquitous environment will be created. These Services will be different according to their location environments like home, office, airport, exhibition, and so on. To provide these localized services to user unconsciously, we need a system that the different sets of services will dynamically drop into the mobile user’s devices depending on their context and manage the distributed localized services efficient. In this paper, we explain the concept and an implementation of Autonomic Service Composition System (ASCS). ASCS can install programs of localized services in user’s mobile device unconsciously and provide localized services to users that are in the local service zone automatically. And ASCS can manage distributed localized services remotely and efficiently. ASCS is composed of Remote Manager, Service Gateway, and Mobile Device. The prototype implementation is done using 802.11b Wireless Network and Bundles using OSGi Framework
Clinical Evaluation of(18)F-PI-2620 as a Potent PET Radiotracer Imaging Tau Protein in Alzheimer Disease and Other Neurodegenerative Diseases Compared With(18)F-THK-5351
Combination of automated brain volumetry on MRI and quantitative tau deposition on THK-5351 PET to support diagnosis of Alzheimer's disease
Imaging biomarkers support the diagnosis of Alzheimer's disease (AD). We aimed to determine whether combining automated brain volumetry on MRI and quantitative measurement of tau deposition on [18F] THK-5351 PET can aid discrimination of AD spectrum. From a prospective database in an IRB-approved multicenter study (NCT02656498), 113 subjects (32 healthy control, 55 mild cognitive impairment, and 26 Alzheimer disease) with baseline structural MRI and [18F] THK-5351 PET were included. Cortical volumes were quantified from FDA-approved software for automated volumetric MRI analysis (NeuroQuant). Standardized uptake value ratio (SUVR) was calculated from tau PET images for 6 composite FreeSurfer-derived regions-of-interests approximating in vivo Braak stage (Braak ROIs). On volumetric MRI analysis, stepwise logistic regression analyses identified the cingulate isthmus and inferior parietal lobule as significant regions in discriminating AD from HC and MCI. The combined model incorporating automated volumes of selected brain regions on MRI (cingulate isthmus, inferior parietal lobule, hippocampus) and SUVRs of Braak ROIs on [18F] THK-5351 PET showed higher performance than SUVRs of Braak ROIs on [18F] THK-5351 PET in discriminating AD from HC (0.98 vs 0.88, P=0.033) but not in discriminating AD from MCI (0.85 vs 0.79, P=0.178). The combined model showed comparable performance to automated volumes of selected brain regions on MRI in discriminating AD from HC (0.98 vs 0.94, P=0.094) and MCI (0.85 vs 0.78; P=0.065)
