Triple antibiotics와 관련한 치아 변색의 예방

Regenerative endodontics has a potential to heal a partially necrotic pulp, which can be beneficial for the continued root development and strengthening of immature teeth. For this purpose, triple antibiotic mixture of ciprofloxacin, metronidazole, and minocycline was recommended as intracanal medicament in an attempt to disinfect the root canal system for revascularization of a tooth with a necrotic pulp. However, discoloration of the tooth was reported after applying this. This case shows the idea for preventing the tooth discoloration using a delivery syringe (SW-O-01, Shinwoo dental) to avoid the contact between the clinical crown and the antibiotics.ope

Comparison of Root Filling Quality of Two Types of Single Cone-Based Canal Filling Methods in Complex Root Canal Anatomies: The Ultrasonic Vibration and Thermo-Hydrodynamic Obturation versus Single-Cone Technique

This study aimed to assess the effectiveness of ultrasonic vibration and thermo-hydrodynamic obturation (VibraTHO) using two types of root canal sealers, in comparison to the single-cone (SC) technique and a calcium silicate-based root canal sealer in complex root canal anatomies. Thirty single-rooted human maxillary premolars with two canals that had a complex root canal anatomy of transverse anastomoses or ramifications were prepared and assigned to the following three experimental groups, according to the filling method: SE group, SC technique with Endoseal TCS; VE group, VibraTHO with Endoseal TCS; and VG group, VibraTHO with GuttaFlow 2. Each tooth was scanned using micro-computed tomography, and the volume percentages of the filling material were calculated. The analysis of variance was used to analyze the statistical differences between the three groups (p < 0.05). The mean volume of the filling material was higher in the VG and VE groups than that in the SE group (p < 0.05) along the apical to middle-to-coronal thirds, and significant differences were observed between each root canal area (p < 0.05), with the only exception being at the apical thirds between the VE and SE groups. The VibraTHO technique using GuttaFlow 2 can be a more effective root canal filling method for anatomically complex root canal systems than the SC technique with Endoseal TCS. On the other hand, the VibraTHO technique using Endoseal TCS has a limited effect on improving the quality of the root filling at the apical portion of anatomically complex root canal systems, compared to the SC technique with Endoseal TCS.ope

Matrix metalloproteinase-8 and substance P levels in root canal exudates of nonvital teeth

OBJECTIVES: The aim of this study was to investigate levels of matrix metalloproteinase-8 (MMP-8) and substance P (SP) in root canal exudates during root canal treatment (RCT) of nonvital, painful teeth. MATERIALS AND METHODS: Patients scheduled for nonsurgical RCT were prospectively selected; the study was performed after obtaining informed consent from the patients and was approved by the Institutional Review Board for Clinical Research of Gangnam Severance Hospital, Yonsei University (3-2008-0118). Canal exudates samples were collected using sterilized paper points from teeth scheduled for RCT across three different time periods. MMP-8 and SP levels were measured using enzyme-linked immunosorbent assay (ELISA). Data were analyzed using a mixed model analysis and the Pearson correlation analysis (p < 0.05). RESULTS: MMP-8 and SP levels in GCF were decreased during RCT (p < 0.0001), and they showed a weak positive correlation to each other (p < 0.05). Patients'subjective pain levels and the response from percussion test were significantly related to SP level. CONCLUSIONS: This study demonstrated that periradicular inflammation endodontic origin can elevate SP and MMP-8 levels in root canal exudates. Interestingly, SP level of canal exudates showed a possibility of being used as an indicator of pain due to periapical pathosisope

Misdiagnosis of florid cemento-osseous dysplasia leading to unnecessary root canal treatment: a case report

This case report demonstrates an unnecessary endodontic treatment of teeth with florid cemento-osseous dysplasia (FCOD) due to a misdiagnosis as periapical pathosis and emphasizes the importance of correct diagnosis to avoid unnecessary treatment. A 30-year-old woman was referred to our institution for apicoectomies of the mandibular left canine and both the lateral incisors. The periapical lesions associated with these teeth had failed to resolve after root canal treatment over a 3-year period. Radiographic examinations revealed multiple lesions on the right canine, the second premolar, and both first molars as well as the anterior region of the mandible. Based on clinical, radiographic and histological evaluations, the patient condition was diagnosed as FCOD. The patient has been monitored for 2 years. To avoid unnecessary invasive treatment, accurate diagnosis is essential before treatment is carried out in managing FCOD.ope

기업의 환경성과 개선 유도 방안: 녹색물류사업을 중심으로

학위논문 (석사)-- 서울대학교 환경대학원 : 환경대학원 환경계획학과 환경관리 전공, 2016. 2. 홍종호.환경문제에 대한 관심이 집중되면서 기업의 수송활동에서의 오염저감에 대한 압박이 거세지고 있다. 수송은 기업활동의 시점에서 종점까지, 즉 전체적인 공급사슬망에 많은 영향을 미친다. 지속가능공급사슬관리 (sustainable supply chain management)는 기업활동의 전 과정에 해당하는 공급사슬망 관리를 통해 오염배출을 감소시키고자 하는 관점을 의미한다. 이는 기업의 수송부문에 대한 녹색물류활동을 증가시키면서 수송을 담당하는 물류기업들이 환경문제에 대한 중심적인 역할을 할 수 있는 잠재력을 가짐을 의미한다. 본 연구는 물류부문에서의 녹색환경활동을 촉진하는 근본적인 개념과 요인을 가려내기 위해 로짓모형을 활용하여 녹색물류사업에 참여하는 기업과 비참여기업 간에 유의미한 요인들을 살펴본다. 이러한 요인들에 대한 물류기업들의 현재의 녹색물류활동과 필요성에 대한 관계를 알아보고 향후 녹색물류에 대한 정책방향을 시사점으로 제시하고자 한다.Pressures on corporations to reduce the pollution impacts of their transport functions, which extends from the beginning to the end of the supply chain, is mounting. Sustainable supply chain management embodies this endeavor and is arising as a key measure to control the impacts of pollution, with logistics service providers having the potential to play a pivotal role in these efforts, through their active role in bringing about green logistics. This research identifies those concepts and factors that underlie the shift to green logistics and determines the extent to which Korean logistics firms are perceiving the needs toward greener logistics. In order to do this, logistic regression is employed to identify statistically significant factors contributing to participation and non-participation in the voluntary government-funded Korean Green Logistics Project.I. Introduction 1 1. Research Background 1 2. Research Purpose and Question 3 3. Research Scope and Methodology 5 II. Conceptual Framework Development 7 1. Sustainability of the Supply Chain and Green Logistics 7 1.1 Value-adding role of the logistics service provider in sustainable supply chain management 7 1.2 Assessing the uptake of green logistics by logistics service providers 9 1.3 Converging to standardized indicators for environmental and economic performance 10 1.4 Environmental certification as motivating the transition to green logistics 13 2. Need for Green Logistics in Anticipation of Strengthening International Climate Change Mitigation Efforts 14 3. Greening Korean Road Transport Logistics 16 3.1 Regulatory efforts to green logistics 16 3.2 Corporate efforts to green logistics 19 3.3 The Green Logistics Project 20 4. Derivation of Categories for Hypothesis Testing 23 III. Methodology 25 1. Hypothesis Development and Assumptions 25 2. Survey Questionnaire 27 3. Binary Logistic Regression 28 IV. Data Collection and Results 31 1. Data 31 1.1 Sampling 31 1.2 Data handling and labeling 32 1.3 Summary statistics 32 2. Results 35 2.1 Model fitting and interpretation 35 2.2 Probability Estimations 38 2.3 Additional note on small sample bias 40 2.3.1 Small sample bias in MLE 40 2.3.2 Firths penalized maximum likelihood estimation to overcome small sample bias 41 2.3.3 Comparison of coefficients 42 V. Conclusion 44 References 46 Abstract 54Maste

Effects of Vocalization on Upper Extremity Motion During Occupational Performance

The purpose of this study was to research the effects of vocalization on upper extremity motion during occupational performance and to compare non-meaning and meaning vocalization. Experiments were performed on 30 subjects. They had no medical history of neurological problems with their upper extremities. Using a tea cup, a tea tray, and a tea spoon, they set a table during vocalization. We used meaning and non-meaning vocalization with the subjects. An example of meaning vocalization would be naming something, and an example of non-vocalization would be saying, "Ah." We used a 3-D analysis system called CMS-HS. We analyzed the motion in the angular velocity and acceleration of the elbow while recording performance time. The results of this study showed that vocalization enhanced the angular velocity and acceleration of the elbow, and also enhanced performance time. In short, vocalization improved upper extremity motion by making it faster and smoother. There were no significant differences between meaning and non-meaning vocalization.ope

Diagnosis and treatment of teeth with primary endodontic lesions mimicking periodontal disease: three cases with long-term follow ups

A tooth with primary endodontic disease that demonstrates a periodontal defect might be extracted because of misdiagnosis as severe periodontal disease or a vertical root fracture. The aim of this case report was to demonstrate the long-term survival of endodontically treated teeth, which had been initially considered unsavable. With meticulous evaluation including the patient's dental history, clinical and radiographic examinations, teeth with primary endodontic lesions could be differentiated and saved after proper root canal treatment. Pain history, vitality test, and radiographic examinations, as well as a general periodontal condition check with periodontal probing on an affected tooth, might be the key methods to differentiate endodontic pathosis from that of periodontal disease.ope

Evaluation of retrievability using a new soft resin based root canal filling material

The aim of this study was to evaluate the retrievability of Resilon as a root canal filling material. Twenty-seven human single-rooted extracted teeth were instrumented utilizing a crown down technique with Gates-Glidden burs and ProFile system. In group1 (n = 12) canals were obturated with gutta percha and AH-26 plus sealer using a continuous wave technique and backfilled. In group 2 (n = 15) Resilon was used as a filling material. Then teeth were sealed and kept in 37℃ and 100% humidity for 7 days. For retreatment, the samples were re-accessed and filling material was removed using Gates-Glidden burs and ProFiles. Teeth were sectioned longitudinally to compare the general cleanliness and amount of debris (× 75) using SEM. Chi-square test was used (α = 0.05) to analyze the data. The total time required for removal of filling materials was expressed as mean ± SD (min) and analyzed by the Student t-test (α = 0.05). Required time for retreatment was 3.25 ± 0.32 minutes for gutta percha/AH 26 plus sealer and 3.05 ± 0.34 minutes for Resilon. There was no statistically significant difference between the two experimental groups. There was no significant difference between the groups in the cleanliness of the root canal wall. This study showed that Resilon was effectively removed by Gates-Glidden burs and ProFiles.ope

In Vivo Experiments with Dental Pulp Stem Cells for Pulp-Dentin Complex Regeneration

In recent years, many studies have examined the pulp-dentin complex regeneration with DPSCs. While it is important to perform research on cells, scaffolds, and growth factors, it is also critical to develop animal models for preclinical trials. The development of a reproducible animal model of transplantation is essential for obtaining precise and accurate data in vivo. The efficacy of pulp regeneration should be assessed qualitatively and quantitatively using animal models. This review article sought to introduce in vivo experiments that have evaluated the potential of dental pulp stem cells for pulp-dentin complex regeneration. According to a review of various researches about DPSCs, the majority of studies have used subcutaneous mouse and dog teeth for animal models. There is no way to know which animal model will reproduce the clinical environment. If an animal model is developed which is easier to use and is useful in more situations than the currently popular models, it will be a substantial aid to studies examining pulp-dentin complex regeneration.ope

Volume Percentage of Filling Voids in Root Canals Prepared by a Novel Nickel-Titanium Rotary System (TruNatomy) Using Two Different Obturation Techniques

This study aimed to compare the volume percentage of filling voids in root canals prepared with a newly introduced rotary system, TruNatomy (Dentsply Maillefer), and obturated by the modified continuous wave (CW) or single cone (SC) filling technique. Plastic tooth models with four canals were enlarged by using TruNatomy files and randomly allocated into either the CW or SC group. The volume percentage of filling voids at 1-6 mm from the apex was analyzed by using microcomputed tomography; mean values were compared by using independent two-sample t-tests (p < 0.05). The mean volume percentages of the filling voids were 2.81 ± 1.11% and 1.77 ± 0.82% in the CW and SC groups, respectively. In the apical area (1-4 mm), volume percentages in the palatal were significantly different between the CW and SC groups; in the middle area (4-6 mm), volume percentages in the palatal and the second mesiobuccal canals were significantly different (p < 0.05). The SC group showed lower volume percentages of filling voids than the CW group. The canals prepared by the TruNatomy system can be obturated well by both the SC and CW techniques. The SC technique showed a lower number of voids, especially in the palatal canals.ope