갈조류와 해면유래의 생리활성천연물에 대한 연구

Thesis(doctors) --서울대학교 대학원 :제약학과(천연물과학전공),2009.8.Docto

New antibiotics of the nocardamine class from a marine-derived Streptomyces sp.

Three cyclic peptides were isolated from the culture broth of the actinomycete Streptomyces sp. isolated from an unidentified marine sponge collected from Jaeju island. These compounds exhibited significant activity against various bacterial strains.2

New bioactive macrolides from the sponge Chondrosia corticata

A series of oxazole-containing macrolides and related metabolites were isolated from the sponge Chondrosia corticata collected form Guam. The structures of three new compounds were defined by combined spectroscopic analyses. These compounds exhibited significant cytotoxicity toward the human leukemia cell ine K562 as well as antifungal activity toward Candida albicans.2

(A) study on the development of marine biological resources in the southwest pacific (A coordinated report of marine biological resources study from 2000 to 2007)

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