Rescue of retinal function by macular translocation surgery in age-related macular degeneration and other diseases with subfoveal choroidal neovascularization

2001-05Age-related macular degeneration (AMD) is the leading cause of legal blindness among the elderly. In AMD and some other macular diseases, subfoveal choroidal neovascularization (CNV) damages the underlying retinal pigment epithelium (RPE), and because retinal function is dependent on a healthy RPE, vision is markedly reduced by a subfoveal CNV. To treat such CNVs, macular translocation surgery has been performed to move the sensory retina from the damaged RPE to healthier RPE. At present, this surgery is the only possible treatment to improve the visual acuity of patients with subfoveal CNV. Macular translocation surgery involves the detachment of the entire retina from the RPE by a subretinal infusion of fluid and creating a 360° circumferential retinotomy followed by the rotation of the retina. Severe postoperative complications such as recurrent retinal detachment have been reported in about 30% of the cases after macular translocation. To determine the efficacy of this surgery, it is necessary to demonstrate an improvement in macular and overall retinal function objectively as well as subjectively. To this end, we have assessed the changes in visual function by measuring the visual acuity subjectively, and the macular function objectively by focal macular ERGs (FERGs). We shall show that there is an improvement in the FERGs in most patients after retinal translocation surgery but the full-field ERGs were reduced by about 30%. Thus, macular translocation surgery with 360-degree retinotomy may be feasible for macular function, although some degree of peripheral retinal function is lost.departmental bulletin pape

幕末期鳥取藩の政治情勢と尊攘激派-岸本辰雄登場の背景-

Articledepartmental bulletin pape

体ほぐしの運動による仲間づくりが児童の自己肯定意識に及ぼす効果 -アドベンチャープログラムを導入した小学校体育授業実践を通して-

text紀要論文 / Departmental Bulletin Paperdepartmental bulletin pape

地域住民コホート研究、東温スタディにおける出生体重と将来の2型糖尿病発症の関連についての検討

優秀演題候補セッションjournal articl

Improved measurements of branching fractions and CP partial rate asymmetries for B-->omegaK and B-->omegapi

journal articl

Stewart, Donald

Donald Stewart - Executive Director of the General Alumni Association. In 1977 he was named editor of the Maine Alumnus.https://digitalcommons.library.umaine.edu/univ_photos/3584/thumbnail.jp

Assessing "Public Deliberation" and "Place"

departmental bulletin pape

Catalpa bignonioides Walt.

原著和名: アメリカキササゲ科名: ノウゼンカズラ科 = Bignoniaceae採集地: 千葉県 千葉市 千葉大学 (下総 千葉市 千葉大学)採集日: 1979/6/15採集者: 萩庭丈壽整理番号: JH026901国立科学博物館整理番号: TNS-VS-97690

Additional file 2: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

and 2–1 show detailed process of MP score computation. (DOCX 106 kb

Additional file 4: of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

shows detailed description of identified drug candidates for breast and prostate cancer. (XLSX 140 kb