11 research outputs found

    アメリカ合州国における銀行・証券分離問題

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    Articledepartmental bulletin pape

    SBML Level 3: an extensible format for the exchange and reuse of biological models

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    Abstract Systems biology has experienced dramatic growth in the number, size, and complexity of computational models. To reproduce simulation results and reuse models, researchers must exchange unambiguous model descriptions. We review the latest edition of the Systems Biology Markup Language (SBML), a format designed for this purpose. A community of modelers and software authors developed SBML Level 3 over the past decade. Its modular form consists of a core suited to representing reaction‐based models and packages that extend the core with features suited to other model types including constraint‐based models, reaction‐diffusion models, logical network models, and rule‐based models. The format leverages two decades of SBML and a rich software ecosystem that transformed how systems biologists build and interact with models. More recently, the rise of multiscale models of whole cells and organs, and new data sources such as single‐cell measurements and live imaging, has precipitated new ways of integrating data with models. We provide our perspectives on the challenges presented by these developments and how SBML Level 3 provides the foundation needed to support this evolution

    SBML Level 3: an extensible format for the exchange and reuse of biological models

    Get PDF
    Systems biology has experienced dramatic growth in the number, size, and complexity of computational models. To reproduce simulation results and reuse models, researchers must exchange unambiguous model descriptions. We review the latest edition of the Systems Biology Markup Language (SBML), a format designed for this purpose. A community of modelers and software authors developed SBML Level 3 over the past decade. Its modular form consists of a core suited to representing reaction-based models and packages that extend the core with features suited to other model types including constraint-based models, reaction-diffusion models, logical network models, and rule-based models. The format leverages two decades of SBML and a rich software ecosystem that transformed how systems biologists build and interact with models. More recently, the rise of multiscale models of whole cells and organs, and new data sources such as single-cell measurements and live imaging, has precipitated new ways of integrating data with models. We provide our perspectives on the challenges presented by these developments and how SBML Level 3 provides the foundation needed to support this evolution.journal articl

    <論説>経営戦略と組織間関係

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    application/pdfdepartmental bulletin pape

    日本の民営化における公共性と企業性(1) : JRとNTTを素材として

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    2000-06-30departmental bulletin pape

    ネットワークセキュリティに関する活動報告 (ネットワークグループ活動報告2001)

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    application/pdfdepartmental bulletin pape

    Induced spectral broadening about a second harmonic generated by an intense primary ultrashort laser pulse in ZnSe crystals

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    The induced spectral broadening about a weak non-phase-matched 530-nm second-harmonic pulse is observed by propagating an intense primary 1060-nm picosecond laser pulse through ZnSe crystals. This broadening is attributed to the induced phase modulation of excitation states.application/pdfjournal articl
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