14 research outputs found

    商工自営業者の意識構造

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    Articledepartmental bulletin pape

    SBML Level 3: an extensible format for the exchange and reuse of biological models

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    Abstract Systems biology has experienced dramatic growth in the number, size, and complexity of computational models. To reproduce simulation results and reuse models, researchers must exchange unambiguous model descriptions. We review the latest edition of the Systems Biology Markup Language (SBML), a format designed for this purpose. A community of modelers and software authors developed SBML Level 3 over the past decade. Its modular form consists of a core suited to representing reaction‐based models and packages that extend the core with features suited to other model types including constraint‐based models, reaction‐diffusion models, logical network models, and rule‐based models. The format leverages two decades of SBML and a rich software ecosystem that transformed how systems biologists build and interact with models. More recently, the rise of multiscale models of whole cells and organs, and new data sources such as single‐cell measurements and live imaging, has precipitated new ways of integrating data with models. We provide our perspectives on the challenges presented by these developments and how SBML Level 3 provides the foundation needed to support this evolution

    SBML Level 3: an extensible format for the exchange and reuse of biological models

    Get PDF
    Systems biology has experienced dramatic growth in the number, size, and complexity of computational models. To reproduce simulation results and reuse models, researchers must exchange unambiguous model descriptions. We review the latest edition of the Systems Biology Markup Language (SBML), a format designed for this purpose. A community of modelers and software authors developed SBML Level 3 over the past decade. Its modular form consists of a core suited to representing reaction-based models and packages that extend the core with features suited to other model types including constraint-based models, reaction-diffusion models, logical network models, and rule-based models. The format leverages two decades of SBML and a rich software ecosystem that transformed how systems biologists build and interact with models. More recently, the rise of multiscale models of whole cells and organs, and new data sources such as single-cell measurements and live imaging, has precipitated new ways of integrating data with models. We provide our perspectives on the challenges presented by these developments and how SBML Level 3 provides the foundation needed to support this evolution.journal articl

    Study on Surface Modification of Mild Steel

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    departmental bulletin pape

    グループウェアの導入と評価報告 (ネットワークグループ活動報告2001)

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    application/pdfdepartmental bulletin pape

    社会保障の内容及び根拠 : ヌスバウムを導きの糸としつつ

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    2000-06-30departmental bulletin pape

    The influence of the Great Meteor Seamount on the distribution of phytoplankton

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    No abstracts are to be cited without prior reference to the author.The influence of the Great Meteor Seamount on the distribution of phytoplankto

    MOESM1 of A non-native macroalga is less attractive for herbivores but more susceptible to light limitation and grazing stress than a comparable native species

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    Additional file 1. The study consisted of three sequential stages: (i) assessing algal light compensation points, (ii) inducing light limitation and grazing and (iii) assessing grazer consumption rates in no-choice feeding assays after light limitation and grazer impact
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