13 research outputs found

    Structure and 1H n.m.r. spectrum of a binuclear copper(I) complex with non-bridging and bridging 2-vinylpyridine ligands (vpy), [Cu 2(μ-vpy)2(vpy)2](ClO4) 2

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    The dimeric copper(I) complex [Cu2(μ-vpy)2(vpy)2](ClO4)2(vpy = 2-vinylpyridine) containing bridging and non-bridging vpy has been synthesized and characterized crystallographically; the CC distance in the co-ordinated vinyl group is slightly longer than those found in unco-ordinated vpy.application/pdfjournal articl

    先進国労使関係の変容と労働者協同組合運動の意義

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    Articledepartmental bulletin pape

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    text紀要論文 / Departmental Bulletin Paperdepartmental bulletin pape

    SBML Level 3: an extensible format for the exchange and reuse of biological models

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    Abstract Systems biology has experienced dramatic growth in the number, size, and complexity of computational models. To reproduce simulation results and reuse models, researchers must exchange unambiguous model descriptions. We review the latest edition of the Systems Biology Markup Language (SBML), a format designed for this purpose. A community of modelers and software authors developed SBML Level 3 over the past decade. Its modular form consists of a core suited to representing reaction‐based models and packages that extend the core with features suited to other model types including constraint‐based models, reaction‐diffusion models, logical network models, and rule‐based models. The format leverages two decades of SBML and a rich software ecosystem that transformed how systems biologists build and interact with models. More recently, the rise of multiscale models of whole cells and organs, and new data sources such as single‐cell measurements and live imaging, has precipitated new ways of integrating data with models. We provide our perspectives on the challenges presented by these developments and how SBML Level 3 provides the foundation needed to support this evolution

    SBML Level 3: an extensible format for the exchange and reuse of biological models

    Get PDF
    Systems biology has experienced dramatic growth in the number, size, and complexity of computational models. To reproduce simulation results and reuse models, researchers must exchange unambiguous model descriptions. We review the latest edition of the Systems Biology Markup Language (SBML), a format designed for this purpose. A community of modelers and software authors developed SBML Level 3 over the past decade. Its modular form consists of a core suited to representing reaction-based models and packages that extend the core with features suited to other model types including constraint-based models, reaction-diffusion models, logical network models, and rule-based models. The format leverages two decades of SBML and a rich software ecosystem that transformed how systems biologists build and interact with models. More recently, the rise of multiscale models of whole cells and organs, and new data sources such as single-cell measurements and live imaging, has precipitated new ways of integrating data with models. We provide our perspectives on the challenges presented by these developments and how SBML Level 3 provides the foundation needed to support this evolution.journal articl

    ウェーバーの大統領制論とワイマル共和国崩壊の憲政史的問題(三・完)

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    2000-06-30departmental bulletin pape

    Levels of Mercury in the Organs of Normal and Acatalasemic Mice Exposed to Metallic Mercury Vapor

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    P(論文)The levels of mercury in the organs of normal and acatalasemic mice exposed to metallic mercury vapor after administration of ethanol or aminotriazole was inves tigated. Levels of mercuric ion in the liver of normal and acatalasemic mice immediately and after 6 hours following exposure to metallic mercury vapor increased in order to mice pretreated with ethanol (ET), pretreated with aminotriazole (AT) and control mice, respectively. Levels of mercuric ion in the lungs of both mice after 6 hours following exposure to mercury vapor decreased than those of mice immediately after exposure. On the other hand, levels of mercuric ion in the liver of both mice pretreated with ethanol or aminotriazole was significantly higher than that of control mice, which indicated that catalase plays a role in oxidizing and taking up mercury. The amounts of metallic mercury in the arterial and orbital venous bloods of normal and acatalasemic mice exposed to metallic mercury vapor were investigated. The amounts of metallic mercury and ratios of metallic mercury to total mercury in the both bloods of acatalasemic mice were significantly higher than those of normal mice. On the other hand, the amounts of total mercury in the both bloods of normal mice were significantly higher than that of acatalasemic mice.departmental bulletin pape
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