Time-resolved deuterium–deuterium fusion born 1 MeV triton confinement study in EAST deuterium plasma

ORCID　0000-0003-4555-1837A time-resolved deuterium–deuterium (D–D) fusion-born triton confinement study, aimed at understanding alpha particle confinement ability, was performed in Experimental Advanced Superconducting Tokamak (EAST) deuterium plasmas for the first time. A scintillating fiber detector was developed for measuring the secondary deuterium–tritium (D–T) neutrons, which provide evidence of triton slowdown, in EAST. The D–D fusion-born triton confinement experiment was performed by measuring secondary D–T neutrons in D-beam-heated D plasma with a plasma current of 400 kA. The secondary D–T neutron signal and its time evolution were obtained using pulse height discrimination analysis. The D–T neutron rate was calculated using the classical energetic ion confinement model to clarify the D–T neutron measurements. The secondary D–T neutron emission rate obtained from the numerical simulation closely agrees with the experimentally obtained results when considering the prompt loss of the tritons.journal articl

Composite of Gadolinium-Labeled Dendrimer Nanocluster And Graphene Oxide Nanosheet for Highly Efficient Liver T1Weighted Imaging Probe

Magnetic resonance contrast agent employs the use of gadolinium chelates, which has many limitations for clinical use including a low contrast effect, a short diagnostic window, and a brief blood circulation time. On this basis, we designed a gadolinium-labeled dendrimer nanocluster (GdDN) loaded graphene oxide nanosheet (GO-GdDN) to boost T1 contrast ability for imaging in vivo and improve blood circulation time. GO-GdDN presented an ultrahigh r1 relaxivity up to 19.07 mM–1 s–1 in a 9.4 T MR scanner, and a bright contrast image in vitro experiment. In addition, GO-GdDN could be internalized by HepG2 cells and presented strong cell contrast enhancement and reduction of the T1 value in HepG2 cells. In vivo, the retention time of GO-GdDN was significantly improved, so that the accumulation of GO-GdDN in liver was enhanced. Moreover, compared to Gd-DTPA, systemic delivery of GO-GdDN dramatically enhanced the signal-to-noise ratio of liver images, which was helpful for accurate imaging of liver and detection of liver lesions in vivo. Thus, this study demonstrates the utility of a powerful diagnosis tool for liver tumor or lesions

Presentation1_Bioinspired skin towards next-generation rehabilitation medicine.PPTX

The rapid progress of interdisciplinary researches from materials science, biotechnologies, biomedical engineering, and medicine, have resulted in the emerging of bioinspired skins for various fantasticating applications. Bioinspired skin is highly promising in the application of rehabilitation medicine owing to their advantages, including personalization, excellent biocompatibility, multi-functionality, easy maintainability and wearability, and mass production. Therefore, this review presents the recent progress of bioinspired skin towards next-generation rehabilitation medicine. The classification is first briefly introduced. Then, various applications of bioinspired skins in the field of rehabilitation medicine at home and abroad are discussed in detail. Last, we provide the challenges we are facing now, and propose the next research directions.</p

Variant genotypes of miRNA processing genes and their associations with risk of HNC.

a<p>Adjusted for age, sex, smoking status and alcohol status.</p

Distributions of selected variables in HNC cases and cancer-free controls.

a<p>Two-sided <i>χ²</i> test.</p>b<p>2 subjects were absent of smoking information and 2 subjects were absent of drinking information.</p>c<p>Including nasal sinuses, parotid and salivary gland.</p>d<p>Including adenocarcinoma, undifferentiated carcinoma and undetermined cancer.</p

DICER 3′UTR luciferase plasmids (T allele or C allele) and chemically synthesized mature has-miR-574-3p expression plasmids in 293T, Hela and Tca8113 cells.

<p>(*, P<0.05; **, P<0.001).</p

Stratified analyses on associations between variant genotypes of rs1057035 and oral cancer risk (Dominant model).

<p>Stratified analyses on associations between variant genotypes of rs1057035 and oral cancer risk (Dominant model).</p

7) 興味ある経過をとった自己免疫性肝炎の1例(一般演題, 第16回リバーカンファレンス総会)

departmental bulletin pape