<Case Report> Intraoperative Brachytherapy of Carcinoma of the Maxillary Sinus

Two patients with advanced carcinoma of the maxillary sinus were treated by intraoperative brachytherapy with a high dose-rate remote afterloading system after conventional radiotherapy with external photon beams. The technique allowed easy insertion of a small Iridium-192 source of high radiation intensity into the area even at a depth where the removal of malignant tissue seemed to be insufficient. However, results in these two cases were not satisfactory, although we feel that, if appropriate patients were selected the technique might be of help in eliminating the little localized tumors remaining after surgery, which are likely to be the source of recurrence.journal articl

Study of double charmonium production in e+e- annihilation at sqrt[s]≈10.6 GeV

journal articl

タイワ オンセイ データベース ノ ジドウ ラベリング ト トウケイテキ ブンセキ ニ モトヅク ハナシ コトバ オンキョウ モデル ノ コウチク

奈良先端科学技術大学院大学修士(工学)master thesi

Analysis of the accessible genomes from <i>C. glutamicum</i>, <i>C. efficiens</i>, <i>C. diphtheriae</i> and <i>C. jeikeium</i>.

<p>The homologous genes of the chaperonin GroEL2 and a poly phosphate kinase PPK2 enclose a presumed conserved porin domain. The operon covering the genes Cg<i>porH</i> and Cg<i>porA</i> whose proteins build the bicomponental main cell wall channel of <i>C. glutamicum</i> is inferred to exist in all strains except for <i>C. jeikeium</i>. Possible terminator sequences of mRNA transcripts were predicted with TranstermHP (indicated by hairpins <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0075651#pone.0075651-Kingsford1" target="_blank">[62]</a>; or were identified manually (marked by asterisk).</p

Identification of effector substances inactivating the repressor protein SugR

<p><b>Copyright information:</b></p><p>Taken from "The DeoR-type transcriptional regulator SugR acts as a repressor for genes encoding the phosphoenolpyruvate:sugar phosphotransferase system (PTS) in "</p><p>http://www.biomedcentral.com/1471-2199/8/104</p><p>BMC Molecular Biology 2007;8():104-104.</p><p>Published online 15 Nov 2007</p><p>PMCID:PMC2222622.</p><p></p> Electrophoretic mobility shift analysis of 15 pmol purified SugR protein complexed with 0.05 pmol of the DNA fragment I2 in the presence of different putative effectors were conducted. Effectors applied to the SugR/I2-complex at varying concentrations as described were A) fructose-1-phosphate (F-1-P), B) fructose-1,6-bisphosphate (F-1,6-P), C) fructose-6-phosphate (F-6-P), and D) glucose-6-phosphate (G-6-P

Electrophoretic mobility shift assays (EMSA) with selected upstream DNA fragments of PTS coding regions using the purified SugR protein

<p><b>Copyright information:</b></p><p>Taken from "The DeoR-type transcriptional regulator SugR acts as a repressor for genes encoding the phosphoenolpyruvate:sugar phosphotransferase system (PTS) in "</p><p>http://www.biomedcentral.com/1471-2199/8/104</p><p>BMC Molecular Biology 2007;8():104-104.</p><p>Published online 15 Nov 2007</p><p>PMCID:PMC2222622.</p><p></p> The physical maps of the extended fructose-PTS gene cluster as well as of the genes and are shown. Beneath the maps the fluorescently labelled PCR fragments are indicated which were used for EMSA studies. These studies were carried out with 15 pmol of purified SugR protein and 0.05 pmol of labeled PCR fragments. The results obtained for each PCR fragment are presented by agarose gel photos. In each picture, the left lane shows the shift in presence of the SugR protein, whereas the right lane shows the negative control without added SugR protein. Transcriptional terminators are denoted as stem loop structures

複数荷重を考慮した線形弾性体の多目的形状最適化(平均コンプライアンス最小化問題を例として)

This paper describes a numerical analysis method for multiobjective shape optimization problems of linear elastic structures. For an example, we treat a multiloading mean compliance minimization problem with a volume constraint. The presented method is based on the traction method that was proposed as a solution to the domain optimization problems by one of the authors. The traction method is implemented to analyze the speed field, which represents the domain variation,with regard to the deformation field of the linear elastic continuum formed in the objective domain applying the force in proportion to the shape gradient function.To scalarize the multiobjective functionals we employ the weighted l_p-norm method with four types of norms.The shape gradient functions for each scalarized objective functional are obtained using the Lagrange multiplier method.For the numerical analyses we used a general-purpose finite-element code.Numerical results to a multiply connected plate problem and to a solid structure problem under the multiloading conditions show the validity of the present method to obtain practical Pareto solutions.journal articl

Average single-channel conductance, G, of purified PorACj in different salt solutions.

<p>The membranes were formed of 1% PC/<i>n</i>-decane. The aqueous solutions were unbuffered and had a pH of about 6 if not indicated otherwise. The applied voltage was 20 mV and the temperature 20°C. The single values represent the means (± SD) of at least 100 single-channel events derived from at least four individual membranes.</p

Alignment of PorACj (JK0268) against the class of PorA and PorH proteins of <i>C. glutamicum</i> ATCC13032, <i>C. glutamicum</i> R, <i>C. efficiens</i> ATCC15991, <i>C. callunae</i> AJ12310, <i>C. diphtheriae</i> ATCC11913 and <i>C. diphtheriae</i> NCTC13129.

<p>The alignment was performed using Pole Bioinformatique Lyonnaise Network Protein Sequence Analysis (<a href="http://npsa-pbil.ibcp.fr" target="_blank">http://npsa-pbil.ibcp.fr</a>) and employing the Clustal W Protein sequences multiple alignments (using the following settings: Gap Opening Penalty: 10; Gap Extension Penalty: 0.2; Protein Weigth Matrix: Gonnet; Gap Separation Distance: 4; Delay Divergent Cutoff (%): 30;). Amino acids identical in all three proteins are highlighted in red (*), strongly similar amino acids (:) are given in green and weakly similar ones (.) in blue. The total number of amino acids is indicated.</p