“Traditional African Medicine” as Living Cultural Heritage : Conditions and Politics of Knowledge Transfer

departmental bulletin pape

小学生を対象としたものづくり教室 ‘ 第三回こども技塾うつのみや’実践報告

text紀要論文 / Departmental Bulletin Paperdepartmental bulletin pape

Search for B-→J/ψΛp̅ decay

journal articl

Machiavelli 2

departmental bulletin pape

トラフィック トクチョウ チュウシュツ ニヨル ネットワーク ウンヨウ シエン シュホウ ニ カンスル テイアン トヒョウカ

奈良先端科学技術大学院大学修士(工学)master thesi

Polymorphism of Long-Chain Alkane-α,ω-Diols with an Even Number of Carbon Atoms

Crystal structures of long-chain alkane-α,ω-diols with an even number of carbon atoms from 20 to 24 are determined. The molecular structures are similar to those of the lower homologues with an even number of carbon atoms analyzed previously; however, the methylene chain packings are different from each other. In the newly analyzed structure, it is found that the crystal structure type has an advantage in the close packing for the methylene part with increasing hydrophobic interactions. Crystal structures of a different polymorphic form in the even number of carbon atoms from 16 to 24 are also determined. The molecular and crystal structures are similar to those of an odd number of carbon atoms analyzed previously. However, the structures are slightly different from self-assembled multilayer structures whose models are derived from a grazing incidence synchrotron X-ray diffraction data. The carbon number starting to exhibit a polymorphic form coincides with that starting to show a rotator phase which are observed just below their melting points. From the viewpoint of the epitaxial growth at the surface and of the calculated density, it is found that the crystal structure of the polymorphic form has an advantage in exhibiting the rotator phase

Masao Maruyama and Takaaki Yoshimoto: What Modern Literary Scholars need to know

論文(Article)第二部(Part2)application/pdfdepartmental bulletin pape

Nucleophilic Additions of Arylzinc Compounds to Aldehydes Mediated by CrCl₃: Efficient and Facile Synthesis of Functionalized Benzhydrols, 1(3<i>H</i>)-Isobenzofuranones, Benzyl Alcohols, or Diaryl Ketones

In the presence of a stoichiometric amount of CrCl3 and trimethylchlorosilane (TMSCl), nucleophilic addition of arylzinc compounds 1c−h to arylaldehydes 2a,b,g smoothly proceeded at room temperature to yield corresponding benzhydrols 4a−f in good yields. From arylzinc compounds 1a,b, 3-aryl-1(3H)-isobenzofuranones 3a−f were given by the CrCl3-mediated reaction with arylaldehydes 2a−f. Diaryl ketones 5a−e were obtained in good yields by the addition of excess amount of benzaldehyde as an oxidant to the resulting solution after the CrCl3-mediated reaction between arylzinc compounds 1c−g and arylaldehydes 2b,g was completed. In the nucleophilic additions of arylzinc compounds 1a,d,f to alkyladehydes 6b−f, the treatment of arylzinc compounds with CrCl3 was required prior to the addition of the aldehydes in order to prevent the fast protodezincation of arylzinc compounds by the enolizable aldehydes. In these CrCl3-mediated nucleophilic additions of arylzinc compounds to aldehydes, arylchromium(III) species are probably reactive intermediates

Gene expression change of monocytes using blood glucose lowering model.

(A) Schematic showing experimental protocol. Eight-week-old db/+ and db/db mice were fed CD or CD mixed with the SGLT2 inhibitor luseogliflozin for an additional 12 weeks. Mice were sacrificed and Ly6Chigh monocytes were sorted from the bone marrow and analyzed. Body weight (B) and blood glucose levels (C) in db/+ and db/db mice treated as described in (A). Results are presented as the means ± SEM. N = 6 mice/group. *p<0.05, **p<0.01. CD, control diet; Ctrl, control; Luse, luseogliflozin. (D) qRT-PCR analysis of expression of the indicated genes in monocytes from mice treated as described in 4A. Data are expressed as the means ± SEM. N = 6 mice/group, *p<0.05, **p<0.01. Luse, luseogliflozin; N.S., not significant. (ANOVA with Fisher’s PLSD).</p

Experimental protocol and flow cytometry results.

(A) Schematic showing experimental protocol. Upper row: Eight-week-old db/+ and db/db mice were fed normal control diet (CD) for an additional 8 weeks. Middle row: Eight-week-old C57BL/6 mice were injected with citrate buffer (vehicle) or streptozotocin (50 mg/kg) once daily for 5 days and fed CD for an additional 8 weeks. Lower row: Eight-week-old C57BL/6 mice were fed CD or a high-fat diet (HFD) for an additional 8 weeks. Mice were sacrificed and bone marrow cells were analyzed by flow cytometry for the ratio of Ly6Chigh to Ly6Clow monocytes. Ly6Chigh monocytes were sorted and analyzed by quantitative RT-PCR. (B-D) Representative flow cytometry dot plots (upper panels) and quantification (lower panels) of CD115+ Ly6Chigh and Ly6Clow in monocytes obtained from the bone marrow of (B) db/db mice and db/+, (C) vehicle- and STZ-treated mice, and (D) Ctrl- or HFD-fed mice. Data are the expressed as the means ± SEM. N = 11 mice/group. Ctrl, control diet; HFD, high-fat diet; STZ, streptozotocin. N.S., not significant. (unpaired t-test).</p