振動を活用したトンネル覆工の変状進展性評価に関する研究

University of Yamanashi (山梨大学)博士(工学)doctoral thesi

Observation of b→dγ and Determination of |Vtd/Vts|

journal articl

Chemical structure of linezolid, the first oxazolidinone antimicrobial compound

<p><b>Copyright information:</b></p><p>Taken from "Update on the appropriate use of linezolid in clinical practice"</p><p></p><p>Therapeutics and Clinical Risk Management 2006;2(4):455-464.</p><p>Published online Jan 2006</p><p>PMCID:PMC1936365.</p><p>© 2006 Dove Medical Press Limited. All rights reserved</p>The first ring (from the left) contains a morpholino group, which enhances its pharmacokinetic profile and improves water solubility. In the second ring (from the left), the strategically located fluorine atom enhances drug activity.The “bridge” structure after the third ring (from the left) bears a necessary 5-(S) configuration.The terminal (right) C-5 acylaminomethyl group is essential for ensuring the unique drug characteristics

締約強制論の現代的展開（五） 契約締結自由の原則の意義と限界を求めて

2007-12-25departmental bulletin pape

Essay on Copper Ore Dressing

工部大学校種別:卒業論文thesi

A Study of Measures to Prevent Tax Avoidance through Profit and Loss Aggregation

亜細亜大学修士（経済学）master thesi

HMG Domain Containing SSRP1 Is Required for DNA Demethylation and Genomic Imprinting in Arabidopsis

In Arabidopsis, DEMETER (DME) DNA demethylase contributes to reprogramming of the epigenetic state of the genome in the central cell. However, other aspects of the active DNA demethylation processes remain elusive. Here we show that Arabidopsis SSRP1, known as an HMG domain-containing component of FACT histone chaperone, is required for DNA demethylation and for activation and repression of many parentally imprinted genes in the central cell. Although loss of DNA methylation releases silencing of the imprinted FWA-GFP, double ssrp1-3;met1-3 mutants surprisingly showed limited activation of maternal FWA-GFP in the central cell, and only became fully active after several nuclear divisions in the endosperm. This behavior was in contrast to the dme-1;met1 double mutant in which hypomethylation of FWA-GFP by met1 suppressed the DNA demethylation defect of dme-1. We propose that active DNA demethylation by DME requires SSRP1 function through a distinctly different process from direct DNA methylation control.journal articl