音声からキーワードを検出する技術の高度化に関する研究

University of Yamanashi (山梨大学)博士(工学)doctoral thesi

Observation of b→dγ and Determination of |Vtd/Vts|

journal articl

MUTAGENIC INTERACTIONS BETWEEN MALEIC HYDRAZIDE AND X-RAYS IN THE STAMEN HAIRS OF TRADESCANTIA CLONE BNL-4430

Mutagenic interactions between maleic hydrazide (MH; a promutagen known to be activated into a mutagen in plant cells) and X rays were studied in the stamen hairs of Tradescantia clone BNL 4430, a blue/pink heterozygote. The young inflorescence-bearing shoots with roots cultivated in the nutrient solution circulating growth chamber were used as tester plants. After determining dose-response curves for X rays and for MH, nine combined treatments with MH (0.5 and 1 mM) and X rays (292 to 1,240 mGy) were conducted, exposing to X rays either 20 or 44 h before, at the midpoint of, or 2 or 44 h after the MH treatments for 4 h. Clear synergistic effects in inducing somatic pink mutations were detected when X rays were given before the MH treatments. On the contrary, however, antagonistic effects were often observed when X-ray treatments were carried out during or after the MH treatments. The synergistic effects detected were thought to be the results of interactions between DNA strand breaks (and the resultant chromosomal breaks) induced by X rays and those by MH, whereas the antagonistic effects observed were presumed to have resulted from X-ray-caused inhibition of the activation of MH in the stamen-hair cells.textapplication/pdfjournal articl

勝野炭山計画

東京帝国大学工科大学種別:卒業論文thesi

Rab33a Mediates Anterograde Vesicular Transport for Membrane Exocytosis and Axon Outgrowth

Axon outgrowth requires plasma membrane expansion, which results from post-Golgi vesicular transport and fusion. However, the molecular mechanisms regulating post-Golgi vesicular trafficking for membrane expansion and axon outgrowth remain unclear. Here, we show that Rab33a expression became upregulated during axon outgrowth of cultured rat hippocampal neurons. Rab33a was preferentially localized to the Golgi apparatus and to synaptophysin-positive vesicles that are transported along the growing axon. Previous studies showed that synaptophysin is localized to post-Golgi vesicles transported by fast axonal transport in developing neurons. Reduction of Rab33a expression by RNAi (RNA interference) inhibited the anterograde transport of synaptophysin-positive vesicles, leading to their decrease in axonal tips. Furthermore, this treatment reduced membrane fusion of synaptophysin-positive vesicles at the growth cones and inhibited axon outgrowth. Overexpression of Rab33a, on the other hand, induced excessive accumulation of synaptophysin-positive vesicles and concurrent formation of surplus axons. These data suggest that Rab33a participates in axon outgrowth by mediating anterograde axonal transport of synaptophysin-positive vesicles and their concomitant fusion at the growth cones.journal articl

Mean per capita out-of-pocket (OOP) payments for health care by states and ETL state groups in India, NSS 2004 and NSS 2014.

Mean per capita out-of-pocket (OOP) payments for health care by states and ETL state groups in India, NSS 2004 and NSS 2014.</p

Inequality in the burden of out-of-pocket health payments across states and ETL groups in India, NSS 2004 and NSS 2014.

Inequality in the burden of out-of-pocket health payments across states and ETL groups in India, NSS 2004 and NSS 2014.</p

Heterogeneities in households with catastrophic health expenditure across states in India, NSS 2014.

NSS = National Sample Survey.</p

Percent change in catastrophic health expenditure (CHE) across states of India from NSS 2004 to NSS 2014.

*For comparison purpose Andhra Pradesh has been considered as an undivided state in NSS 2014. NSS = National Sample Survey.</p

Households with catastrophic health expenditure (CHE) across ETL state groups by MPCE quintiles in India, NSS 2004 and NSS 2014.

Households with catastrophic health expenditure (CHE) across ETL state groups by MPCE quintiles in India, NSS 2004 and NSS 2014.</p