29 research outputs found

    Observation of b→dγ and Determination of |Vtd/Vts|

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    journal articl

    Design of the Working of the Wanibuchi Mine(鰐淵鉱山計画)

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    東京帝国大学工科大学種別:卒業論文thesi

    十七世紀の福建寧化県における黄通の抗租反乱(一)

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    1973-03-31departmental bulletin pape

    IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes.

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    Adult multipotent neural progenitor cells can differentiate into neurons, astrocytes, and oligodendrocytes in the mammalian central nervous system, but the molecular mechanisms that control their differentiation are not yet well understood. Insulin-like growth factor I (IGF-I) can promote the differentiation of cells already committed to an oligodendroglial lineage during development. However, it is unclear whether IGF-I affects multipotent neural progenitor cells. Here, we show that IGF-I stimulates the differentiation of multipotent adult rat hippocampus-derived neural progenitor cells into oligodendrocytes. Modeling analysis indicates that the actions of IGF-I are instructive. Oligodendrocyte differentiation by IGF-I appears to be mediated through an inhibition of bone morphogenetic protein signaling. Furthermore, overexpression of IGF-I in the hippocampus leads to an increase in oligodendrocyte markers. These data demonstrate the existence of a single molecule, IGF-I, that can influence the fate choice of multipotent adult neural progenitor cells to an oligodendroglial lineage.journal articl

    Unadjusted and adjusted odds ratios (OR) and 95% confidence intervals (CI) of Metabolic Syndrome: Results from logistic regression analyses.

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    <p>OR = odds ratio; CI = confidence interval.</p><p>*Data on literacy and marital status were missing for 3 participants.</p>#<p>Data on asset index was missing for 24 persons.</p>§<p>Data on Nutritional status was missing for 13 persons.</p>a<p>ORs (95% CIs) were derived from the model that included age, sex, literacy, marital status, asset index, smoking, tobacco leaf and nutritional status.</p
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