10 research outputs found

    Nursing role in end of life care supporting

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    終末期を在宅で過ごす患者は、病状の進行等の理由により、在宅療養が困難となることが多い。今回、多くの医療者が関わり、患者の病状に合わせた必要な治療やケアをおこなうことで、9ヶ月間の在宅療養を支えることができた症例を経験した。この症例を通して、終末期を在宅で過ごす患者・家族への関わりとして、早期からの医療チームによる支援、外来看護師による情報収集・伝達、医療チーム間の連絡調整、患者・家族の精神面での支援が必要であることがわかった。Article信州大学医学部附属病院看護研究集録 38(1): 93-98(2009)departmental bulletin pape

    Improved Search for νμ→νe Oscillation in a Long-Baseline Accelerator Experiment

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    journal articl

    palustris

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    Poa palustris Linnaeusfowl bluegrass;fowl meadow grass;swamp bluegrasspâturin des marais;pâturin palustre;pâturin de la baie d'Hudson;pâturin tardifpalustris4.2 km NE of CouttsDry Mixed Grass: rolling prairie - wet to moist slough meadow3440 feetBeckmannia, Polygonum, Poa, Hordeum, Potentilla, Eleocharis, Rumex, Juncu

    飯盛鉱山計画

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    東京帝国大学工科大学種別:卒業論文thesi

    前方文脈を考慮した定冠詞theの推定

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    application/pdf三重大学大学院工学研究科博士前期課程情報工学専攻30thesi

    Psychological coping with elevation : preliminary approaches to the effect of residence in multi-storied housing

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    1994-03The present study is concerned with elevation as a variable of residential environment of multistoried housing and examines its psychological and behavioural effects. In the first part, housewives who had lived in multistoried housings were asked to respond to a questionnaire consisted of 32 items including different aspects; cognition and evaluation of environment, positive and negative emotion aroused, interpersonal relations, and daily behaviours. The result showed that resident's emotional arousal was reduced with lapse of time. In the second part, accidents of falling down from elevation were analyzed, since the author paid much attention to a tendency that accidents of this type had increased. Accidents mostly occurred in familiar places. They were attributable to insufficient attention to environment and/or reduced fear of elevation.Youngsters tend to give rise to accidents. These findings suggest that the increasing tendency of this type of accidents reflects the desensitization facilitated by livingat an elevated place. It is 'overadaptation' to the environment. In the third part, attempt was done to assess different visual environments by comparing their effects on the performance of a judgmental task (selective reaction time; RT). Elevation delayed and dispersed RTs, making the response erroneous. This suggests that elevation arouses psychological tension (fear) more strongly and that living experience reduces the fear of height.departmental bulletin pape

    ブライ ン中の有機物に関する研究

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    application/pdfpostprintThe identification and quantitative analysis of organic compounds dissolved in brines circulating through mercury type Cl₂-caustic electrolytic processes were carried out by means of gas chromatograph-mass spectroscopy and gas chromatography. The possibility of a formation of CH₃HgCl by the reactions of HgCl₂ with halogenated organic compounds were also studied at 70℃ in brine (NaCl 300g/l, pH5.8 and 11.8). The results obtained as followed; (1) The dissolved compounds in brines were founds such as CH₃Cl, CH₂Cl₂, CHCl₃, CH₂ ClCH₂Cl, CH₃3Br, CHBrCl₂, and CHBr₃. (2) Among these compounds, especially, contents of CH₂Cl₂, CHCl₃ and CH₂ClCH₂Cl in brines were 0.X ppm order. (3) A substance estimated as CH₃HgCl was scarcely detected at pH11.8 and not detected at pH5.8 by above-mentioned reactions.departmental bulletin pape

    Calcium signalling mediates self-incompatibility response in the Brassicaceae

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    ARC1 is known to interact with, and is phosphorylated by, the kinase domain of SRK in Brassica napus9,10. ARC1 is a U-box protein with E3 ubiquitin ligase activity11, and interacts with Exo70A112, a putative component of the exocyst complex, which generally functions in polarized secretion13. These results suggested a model in which activated SRK phosphorylates ARC1, leading to the preclusion of as-yet unknown ‘compatibility factors’ secretion to the stigmatic surface and inhibiting pollen entrance14. However, the suppression of ARC1 expression results in incomplete breakdown of self-incompatibility in both B. napus and Arabidopsis lyrata10,14, and self-compatible Arabidopsis thaliana that lacks ARC1 acquires the self-incompatibility phenotype by introducing SRK and SP11/SCR genes15. Therefore, the extent ARC1 to which is involved in the signalling pathway downstream of SRK remains unclear8,16,17.In this study, we focused on investigating the cytoplasmic Ca2+ dynamics in stigma papilla cells during the self-incompatibility response. A previous study injected dyes to monitor Ca2+ dynamics in the self-incompatibility response18. By combining the in vivo imaging using genetically encoded [Ca2+]cyt probes and pharmacological approaches, we found that cytoplasmic Ca2+ drastically increases in the papilla cells after self-pollination, which can be efficiently blocked by the inhibitors of glutamate receptor channels that mediate the influx of extracellular Ca2+. Pretreatment of papilla cells with glutamate receptor channel inhibitor compromised the self-incompatibility response in vivo, whereas an artificial increase in [Ca2+]cyt in papilla cells induced arrest of pollen hydration to compatible pollen. The [Ca2+]cyt increase in papilla cells during the self-incompatibility response of GLR mutants was significantly reduced. Our results overall strongly suggest that the Ca2+ influx in papilla cells mediated by GLR is the key self-incompatibility response that leads to self-pollen rejection.Self-incompatibility in the Brassicaceae is controlled by multiple haplotypes encoding the pollen ligand (S-locus protein 11, SP11, also known as S-locus cysteine-rich protein, SCR) and its stigmatic receptor (S-receptor kinase, SRK). A haplotype-specific interaction between SP11/SCR and SRK triggers the self-incompatibility response that leads to self-pollen rejection, but the signalling pathway remains largely unknown. Here we show that Ca2+ influx into stigma papilla cells mediates self-incompatibility signalling. Using self-incompatible Arabidopsis thaliana expressing SP11/SCR and SRK, we found that self-pollination specifically induced an increase in cytoplasmic Ca2+ ([Ca2+]cyt) in papilla cells. Direct application of SP11/SCR to the papilla cell protoplasts induced Ca2+ increase, which was inhibited by D-(?)-2-amino-5-phosphonopentanoic acid (AP-5), a glutamate receptor channel blocker. An artificial increase in [Ca2+]cyt in papilla cells arrested wild-type (WT) pollen hydration. Treatment of papilla cells with AP-5 interfered with self-incompatibility, and Ca2+ increase on the self-incompatibility response was reduced in the glutamate receptor-like channel (GLR) gene mutants. These results suggest that Ca2+ influx mediated by GLR is the essential self-incompatibility response leading to self-pollen rejection.Flowering plants have developed self-incompatibility as a genetic system to prevent inbreeding and thus promote outcrossing. In many species, self-incompatibility is controlled by an S locus with multiple haplotypes1. Each S-haplotype encodes both male- and female-specificity determinants (S-determinants), and self/non-self-discrimination is accomplished by the S-haplotype-specific interaction between these S-determinants.In the Brassicaceae, the male and female S-determinants have been identified as SP11/SCR and SRK, respectively1. SP11/SCR is a polymorphic small peptide secreted from the anther tapetum that localizes to the pollen surface, whereas SRK is a polymorphic Ser/Thr receptor kinase that localizes to the plasma membrane of stigma papilla cells. SP11/SCR and SRK from each S-haplotype function respectively as a ligand and its cognate receptor. Upon self-pollination, the S-haplotype-specific interaction between SP11/SCR and SRK induces autophosphorylation of SRK, which is thought to trigger a signalling cascade in the papilla cells, resulting in the rejection of self-pollen2. Although self-pollination is known to evoke multiple physiological changes in the papilla cells, including disruption of actin bundles, fragmentation of vacuolar structure and modification of microtubules3,4, the signalling pathway downstream of SRK that leads to these processes remains largely unknown.Thus far, two candidate molecules, M-locus protein kinase (MLPK) and Arm-repeat containing 1 (ARC1), have been identified as the direct downstream effectors of SRK. MLPK was identified as a gene responsible for a self-compatibility mutation in Brassica rapa5, and encodes a membrane-anchored cytoplasmic protein kinase that interacts with SRK on the papilla cell membrane6. Recent studies have suggested that MLPK is also involved in intraspecies unilateral incompatibility of B. rapa7, but it remains unclear whether MLPK is required for self-incompatibility throughout the Brassicaceae.journal articl

    自律分散型ロボットシステムにおける通信を用いた協調チーム編成手法の開発と評価

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    In this paper, a method of organizing for a collaborating team in a distributed autonomous robotic system, ACTRESS, is discussed. In this system, plural robotic agents are organized in a collaborating team, in which they cooperate to execute a common task. All agents are equipped with a communication system. An efficient negotiation method is developed to organize an optimal team. It utilizes the record of past negotiations. The robotic agents in a collaborating team exchange messages which contain the functional status of robotic agents, record these data in their own knowledge-bases, and select cooperative agents. In the learning mechanism, the robotic agent calculates suitability of cooperative agents in the collaborating team in advance, using its knowledgebase, and negotiates the organization of the collaborating team with a limited number of agents. With this learning mechanism, efficient negotiation is achieved, which is verified by simulation.rights: 社団法人日本機械学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation: IsVersionOf: http://ci.nii.ac.jp/naid/110002382041/textapplication/pdfjournal articl
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