7 research outputs found
Gemcitabine plus carboplatin in patients with advanced non-small-cell lung carcinoma : phase I/II study of 28-day schedule
Get PDFUniversity of Yamanashi (山梨大学)博士(医学)医工博乙第61号 山梨医科学雑誌 Vol.27 no.2 page.51-58 (2013)doctoral thesi
Validity and reproducibility of the intake of trans-fatty acids estimated using a Food Frequency Questionnaire and characteristics of trans-fatty acid intake of the Japanese population: The JPHC FFQ Validation Study
Get PDFWe aimed to validate a method for assessing trans-fatty acid (TFA) intake in the Japanese population using the FFQ developed in the 1990s from a prospective study that was based on the Japan Public Health Center-based Prospective Cohort Study. For FFQ validation, we included 565 participants (Cohort I: n 215, Cohort II: n 350) aged 40–69 years. We used a 28-d dietary record (DR) over 1 year and two FFQ administered before and after DR assessment. We calculated total TFA intake, TFA from industrial oils (i-TFA) and TFA from ruminants (r-TFA) considering a database of measurements obtained mainly from Japan. Spearman’s rank correlation coefficients (CC) were computed for validity and reproducibility. Energy adjustments were applied using two methods considering the TFA measurement: density method for TFA % of total energy and residual method for TFA g/d. The total TFA intake (% of the total energy intake) was 0·08–0·76 % (median, 0·27–0·37 %) in DR of both cohorts and was 0·00–1·13 % (median, 0·30–0·40 %) in FFQ. The i-TFA accounted for approximately 50 % of the total TFA intake in DR and approximately 40 % in FFQ. For total TFA (% of the total energy intake), CC were 0·54–0·69, and weighted κ coefficients were 0·88–0·92 for both cohorts. The de-attenuated CC was 0·46–0·62 for i-TFA (g/d) and 0·57–0·68 for r-TFA (g/d). Our study showed that the validity and reproducibility of TFA intake estimation using the FFQ were reasonable, suggesting its suitability among the Japanese population with low-TFA intake.journal articl
Improved Constraints on D0-D̅0 Mixing in D0→K+π- Decays from the Belle Detector
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Colony-live --a high-throughput method for measuring microbial colony growth kinetics-- reveals diverse growth effects of gene knockouts in Escherichia coli
Get PDFPrecise quantitative growth measurements and detection of small growth changes in high-throughput manner is essential for fundamental studies of bacterial cell. However, an inherent tradeoff for measurement quality in high-throughput methods sacrifices some measurement quality. A key challenge has been how to enhance measurement quality without sacrificing throughput.journal articl
