Effects of combined one-lung ventilation and intrathoracic carbon dioxide insufflation on intrathoracic working space when performing thoracoscopy in dogs

OBJECTIVE To evaluate the effects of combining one-lung ventilation and carbon dioxide insufflation (OLV-CDI) on intrathoracic working space (determined by means of CT) during thoracoscopy in dogs and investigate conditions that could safely improve working space compared with OLV alone. ANIMALS 6 healthy Beagles. PROCEDURES Dogs were anesthetized, and right- or left-sided (n = 3/side) OLV was instituted. On the blocked side, a laparoscopic trocar sleeve was placed in the ninth intercostal space for CDI. CT was performed under 3 conditions: with OLV alone, with OLV-CDI at an intrapleural pressure (IPP) of 3 mm Hg, and with OLV-CDI at an IPP of 5 mm Hg. Working space volume (WSV), ventilation space volume (VSV), and thoracic cavity volume (TCV) were determined from CT images. RESULTS With OLV-CDI at an IPP of 3 or 5 mm Hg, WSV and TCV were significantly increased, compared with values obtained during OLV alone. With OLV-CDI at an IPP of 5 mm Hg, VSV and Spo2 were significantly decreased, compared with values obtained during OLV alone. Additionally, contralateral pneumothorax was observed in 4 dogs at an IPP of 5 mm Hg. CLINICAL RELEVANCE Combining OLV and CDI could provide a larger working space than OLV alone, even with an IPP of 3 mm Hg, in dogs of limited size. However, an evaluation of the effects on oxygenation and cardiovascular variables is needed before clinical use.journal articl

Improved Constraints on D0-D̅0 Mixing in D0→K+π- Decays from the Belle Detector

journal articl

Determination of Trace Elements in River Arakawa(Regional Information Management)(<Special Issue>FID)

The river stems from a mountain, runs through the land and flows in the sea. She covers the area of the mountain side, that of the agricultural field and that of the city which is crowded by the people. The function is important for the sustenance of the good life of people of good quality, because the river water in the country side area works as the source of the ground water which is used in the daily life, and works in the agricultural field as that of the irrigation water for the rice and vegetables. Moreover, in the modern days, the river has a key function in the city life as the source of tap water. Accordingly, the data on the quality of the river water are the controls of great importance for the human activities of modern days. How we can meet this condition of the river? We should recognize the river as a system of information, where creation of information (data production), data accumlation, then networking of those data must be formulated as a system. For data creation, experimental science must work. For systematization of the data, information scientists should join and work. Top level work in the experimental science is needed for data creation. Patient and enormous efforts are also necessary for accumlation of the data. This report will call the attention of the information scientists for the fact that the subject of the experimental science needs the eyes of information scientists. Human lives of modern time hold the danger of having hazardous chemical substances in water which needs chronological monitoring. But, first of all, the methods of measurement of those substances with the highest sensitivity and accuracy must be invented, and then this method must be applied in reality. This paper will report the results of the invention of the method and application of the said method for six monitoring sites of the river. As a matter of the future problem, the on-line base data access and the networking of those monitoring stations must be materialized, although some experimental stations are already being built in this country. This paper will be presented as an example which refers to the importance of the eyes to see the river as an information system which bridges multiphases of the modern lives.rights: 情報知識学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation: IsVersionOf: http://ci.nii.ac.jp/naid/110003375683/textapplication/pdfjournal articl

Membrane Modification for Ion Separations and Drug-target Identification

Cation-exchange membranes modified with polyelectrolyte multilayers (PEMs) could provide a platform for lithium purification based on the large hydrated radius and hydration energy of lithium relative to the corresponding values for other alkali metal ions. The PEMs give rise to Li+ selectivity, and the cation-exchange membrane allows separation through either Donnan dialysis (DD) or electrodialysis. Alternating adsorption of protonated poly(allylamine hydrochloride) (PAH) and poly(4-styrenesulfonate) (PSS) on Nafion 115 membranes increases the K+/Li+ DD selectivity and with source phases containing 0.01 M HNO3, the K+/Li+ selectivity reaches ~60. However, more recent studies suggest this may depend on the batch of cation-exchange membranes. Ellipsometric studies show increased PEM swelling at low pH, which may open cation-exchange sites that preferentially bind K+ to enable highly selective transport. Subsequent studies modified the interior of porous membrane with PEMs to allow attachment of small-molecule drugs and identification of their protein targets. A model system of carbonic anhydrase II (CAII) binding to immobilized 4-(2-aminoethyl)benzenesulfonamide (AEBSA) demonstrates the efficiency and selectivity of affinity capture in modified membranes. Selective elution of captured protein, tryptic digestion, tandem mass spectrometry analysis, and label-free quantification (LFQ) identify CAII as the dominant AEBSA target in diluted serum or cell lysate Global proteomics shows that the spiked CAII is the only protein with a log2 ratio (sample/control intensity) consistently >2, and the detection limit for CAII identification is 0.004 wt% of the total protein in 1:4 diluted human serum or 0.024 wt% of the total protein from breast cancer cell lysates. The same approach also identifies native CAII in human kidney cell lysate as an AEBSA target.Comparison of affinity capture using membranes, Affi-Gel 10 resin or M-270 Dynabeads derivatized with AEBSA suggests that only membranes allow identification of low-abundance CAII as a target.</p

bending test-sub.mp4

When the transparent LED screen is being dynamically bent into a radius as small as about 15 mm, the LEDs can still work

線材と板材とのパーカッション溶接部の継手強度に及ぼす加圧方式の影響

application/pdf三重大学大学院工学研究科 博士前期課程 機械工学専攻 材料機能設計研究室80thesi

Result of the antisaccade task.

Inhibition is the key factor of attentional control (AC). Basketball players are typically exposed to noise from the audience or opposing teams while competing. These distractions disrupt the attentional systems, ultimately compromise the athletes’ inhibition ability and directly affect their performance on the court. Hence, effective AC strategies are crucial. Two studies were demonstrated to investigate the effects of noise distractions on attentional control and the moderating effect of self-talk. In Study 1, 36 participants undertook the Stroop task, showing an increased error rate with noise distraction. Thirty-nine national second-level basketball players participated in Study 2, where they engaged in the Antisaccade task under both quiet and noise-distraction conditions, employing different self-talk strategies. Results showed that instructional self-talk reduced the antisaccade error rate in quiet conditions, while motivational self-talk increased the error rate under noise distractions. These findings suggests that noise distraction reduces AC. In competition scenarios, basketball players are required to appropriately implement self-talk strategies to improve AC and prevent potential counterproductive effects.</div

Antisaccade task.

A 1000ms “ready” was presented first, followed by a 1000ms cross fixation, which the participant needed to look at before the cross fixation disappeared, otherwise it was considered an invalid trial. The distractor stimulus was then presented for 600ms, followed by a 200ms arrow after the distractor stimulus disappeared. After the arrow vanishes, a circular stimulus appears and remains until the participant responds to the arrow’s direction.</p

Image_1_Individual differences in the language task-evoked and resting-state functional networks.jpg

The resting state functional network is highly variable across individuals. However, inter-individual differences in functional networks evoked by language tasks and their comparison with resting state are still unclear. To address these two questions, we used T1 anatomical data and functional brain imaging data of resting state and a story comprehension task from the Human Connectome Project (HCP) to characterize functional network variability and investigate the uniqueness of the functional network in both task and resting states. We first demonstrated that intrinsic and task-induced functional networks exhibited remarkable differences across individuals, and language tasks can constrain inter-individual variability in the functional brain network. Furthermore, we found that the inter-individual variability of functional networks in two states was broadly consistent and spatially heterogeneous, with high-level association areas manifesting more significant variability than primary visual processing areas. Our results suggested that the functional network underlying language comprehension is unique at the individual level, and the inter-individual variability architecture of the functional network is broadly consistent in language task and resting state.</p

Demographic information and manipulation check.

Inhibition is the key factor of attentional control (AC). Basketball players are typically exposed to noise from the audience or opposing teams while competing. These distractions disrupt the attentional systems, ultimately compromise the athletes’ inhibition ability and directly affect their performance on the court. Hence, effective AC strategies are crucial. Two studies were demonstrated to investigate the effects of noise distractions on attentional control and the moderating effect of self-talk. In Study 1, 36 participants undertook the Stroop task, showing an increased error rate with noise distraction. Thirty-nine national second-level basketball players participated in Study 2, where they engaged in the Antisaccade task under both quiet and noise-distraction conditions, employing different self-talk strategies. Results showed that instructional self-talk reduced the antisaccade error rate in quiet conditions, while motivational self-talk increased the error rate under noise distractions. These findings suggests that noise distraction reduces AC. In competition scenarios, basketball players are required to appropriately implement self-talk strategies to improve AC and prevent potential counterproductive effects.</div