境界要素法とノイマン級数に基づく摂動解法を組合せた起伏地形の地震応答解析手法

山地や谷地形などの地形の起伏や，埋没谷などの基盤の不整形性を有する地盤では複雑な地震応答を示すことが指摘されている。このため様々な地震応答解析が行われているが，複雑な応答が生じるメカニズムについ　ては依然として不明な点が多い．本研究では，地表面の起伏に着目し，起伏が地震応答に与える影響を検討するための手法として，境界要素法と摂動解法を組み合わせた新たな手法を展開した．この手法には地震応答を入射波と次数ごとの散乱波の寄与に分離できる利点がある．また，本解析手法の適用例を示し，地盤の応答関数が散乱波の寄与から解釈できること，散乱波の寄与は散乱波の発生地点の地表面の法線方向とこの地点から地震応答を考える地点への方向との関係，及び両地点の距離の二つの要因の影響を受けることなどを指摘した It has been pointed out that the ground with an irregular surface causes complicated seismic responses. However, the process of generating this complex response is not yet clarified. In this study, boundary element-perturbation method has been developed to investigate scattering of seismic waves due to an irregular surface. This method is based on the boundary element method in frequency domain and perturbation technique employing the Neumann series. By using this method, the ground response can be separated into those induced by incident waves and scattered waves. Numerical results showed that the amplitudes of the scattered waves are affected by both distance and direction of the irregular surface to the observation points.textapplication/pdfjournal articl

Role of orexin receptors in histamine- and chloroquine-induced pruriceptive processing

It is known that orexin peptides are involved in nociceptive processing, while little is known about the roles of these peptides in itch processing. To reveal the functions of orexin peptides in pruriceptive processing, orexin A (OX-A) and orexin B (OX-B) were applied before histamine or chloroquine (CQ). The administration of OX-A reduced the numbers of scratching events and c-Fos positive cells induced by histamine and CQ, but not OX-B. To clarify the involvement of orexin receptors in pruriceptive processing, OX-A was administered after the injection of an orexin receptor type 1 (OX1) antagonist (SB334867) or an orexin receptor type 2 (OX2) antagonist (JNJ10397049) before histamine and CQ injections. The attenuating effects of OX-A on histamine- and CQ-induced scratching events were reversed by JNJ1039 and SB334867, respectively. To confirm the role of OX2 receptor, an OX2 receptor agonist (YNT185) was applied before the injection of histamine or CQ. Scratching events and c-Fos expression induced by histamine, but not CQ, were attenuated by the pretreatment with YNT185. These results indicate that OX-A elicits the attenuating effects in pruriceptive processing and that itch signals induced by histamine and CQ appear to be differentially regulated by the OX2 receptors and OX1 receptors

COLLECTING OF SIMULTANEOUS INTERPRETATION PATTERNS USING BILINGUAL SPOKEN LANGUAGE CORPUS

This paper provides an investigation of simultaneous interpreting patterns using a bilingual spoken monologue corpus. 4,578 pairs of English-Japanese aligned utterances in CIAIR simultaneous interpretation database were used. This investigation is the largest scale as the observation of simultaneous interpreting speech. As a result, we collected 203 cases out of aligned utterances in which simultaneous interpreters' strategies for raising simultaneity were observed. These 203 cases could be categorized into 12 types of interpreting pattern. These interpreting patterns can be expected to be used as interpreting rules of simultaneous machine interpretation.conference pape

Milling and Cyaniding of the Sado Mine＇s Low Grade Ore（佐渡鉱山採鉱及青化製煉計画）

東京帝国大学工科大学種別:卒業論文thesi

Current Status of Pediatric Fever Outpatient Division During the Outbreak of COVID-19

application/pdf峡南医療センター富士川病院の小児発熱外来では，新型コロナウイルス感染症の診察前検査を延べ544例で行った。新型コロナウイルス感染症患者と診断されたのは9例(1.65％)で，受診契機は非新型コロナウイルス感染症患者と比較し，保健所からの依頼，接触歴，頭痛，咽頭痛が有意に多かったが（順にP＝0.007, P < 0.0001, P =0.014, P =0.042），発熱の有無や最高体温に差を認めなかった。複数回受診者220例（40.4％）は，１回受診者に比し，有意に低年齢（平均年齢4.7歳対7.0歳，P＜ 0.0001）で，鼻汁（65.5％対46.7％，P＝0.0003），咳嗽(54.1％対 38.6％，P＝0.0004）が多く，咽頭痛（17.7％対24.1％，P＝0.0099）が少なかったが，発熱率や最高体温に差を認めなかった。小児発熱外来での診察前検査は，新型コロナウイルス感染症患者と一般外来患者との接触機会の減少に寄与した。journal articl

Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice

Citation: Haruta-Tsukamoto A, Miyahara Y, Funahashi H, Nishimori T, Ishida Y. Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice. Biochem Biophys Res Commun. 2020 Dec 17;533(4):1102-1108. doi: 10.1016/j.bbrc.2020.09.109. Epub 2020 Oct 4. PMID: 33028486