The Review of psychological studies on romantic relationships of university students : The pursuit of ways to help for clients' resolution of romantic relationship problems in student counseling

本研究は，学生相談における恋愛問題解決支援のあり方を探求するために，国内外の大学生の恋愛に関する心理学的研究を概観することを目的とした。研究１では，学術情報データベースを用いて収集した国内外の査読学術論文を概観した。その結果，国外の研究論文が４５本，国内の研究が２１本収集された。恋愛関係進展度別に論文数を調べたところ，国外，国内ともに恋愛関係継続時の論文が最も多かった。研究１の結果，国内における事例研究が皆無であったことから，恋愛問題の解決を部分的に支援している事例研究の有無とその特徴を概観することを目的に研究２を実施した。研究２では，青年の事例研究を多く掲載している３つの学術誌（心理臨床学研究，学生相談研究，精神分析研究）から収集した。その結果，３９本の論文が収集された。また，女性クライエントが女性セラピストに対して，母親からの情緒的応答の体験不足の影響と思われる恋愛関係継続時の悩みを訴える事例研究が最も多いという特徴が見られた。これらの結果から，学生相談において恋愛問題解決を支援する際には，背景に養育者の情動的応答体験不足があることを理解した上で，セラピストが適切な情動的応答を行なうことが肝要であることが示唆された。This paper reviews psychological studies on university students’romantic relationships with the goal of supporting relationship problem resolution in student counseling. In Study 1, we collected and reviewed domestic and foreign peer-reviewed papers from academic information databases. As a result, we collected forty-five foreign and twenty-one domestic papers. We counted the number of papers according to the progress of students' romantic relationships, and found that most papers concerned the continuation of romantic relationships. Because the domestic papers reviewed in Study 1 did not include case studies, in Study 2 we examined domestic case study papers on support for partial resolution of romantic relationship problems. We collected thirty-nine papers from three academic journals and found that in the case studies, female clients who experienced a lack of proper emotional responses from their mothers sought counseling from female counselors on how to continue their romantic relationships. From results of this study, we found that it is important for therapists to understand the effects of lack of clients' experiences of emotional responses from their caregivers and to help to resolve clients' romantic relationship problems with proper emotional responses.departmental bulletin pape

Comparison of one-year real-world outcomes between red (670 nm) subthreshold micropulse laser treatment and intravitreal aflibercept injection for treatment-naïve diabetic macular edema

Purpose To evaluate the treatment outcomes of subthreshold micropulse laser (SMPL) with a wavelength of 670 nm (red) for treatment-naïve diabetic macular edema (DME). Methods A retrospective observational study which included 42 eyes in 34 patients diagnosed with treatment-naïve DME was conducted. Twenty-one eyes underwent red SMPL and the other 21 eyes underwent intravitreal injection of aflibercept (IVA) as initial treatment and were followed up for 12 months. Best-corrected visual acuity (BCVA), central retinal thickness (CRT) on optical coherence tomography (OCT), vessel density (VD), and foveal avascular zone area on OCT angiography (OCTA) were measured and compared between the two groups. Results In the red SMPL group, the mean BCVA slightly improved from 0.29 ± 0.28 at baseline to 0.22 ± 0.29 at 12 months (p = 0.18), while the mean CRT significantly decreased from 472 ± 200 µm at baseline to 320 ± 136 µm at 12 months (p = 0.003). At 12 months from baseline, the mean change in BCVA and CRT were similar between the red SMPL and IVA groups (p = 0.79 and p = 0.31, respectively). No significant change was detected in OCTA parameters except for VD at the nasal section in the red SMPL group. Conclusion Red SMPL for treatment-naïve DME maintained BCVA and significantly reduced CRT at 12 months. These treatment outcomes were equivalent to IVA in real-world settings, which tend to be inferior to clinical trials

Association of Polyp Regression after Loading Phase with 12-Month Outcomes of Eyes with Polypoidal Choroidal Vasculopathy

Purpose: We compared 12-month outcomes of eyes with polypoidal choroidal vasculopathy (PCV) with or without complete regression of polyps observed one month after three monthly intravitreal administrations (loading phase) of aflibercept (2.0 mg/0.05 mL) or brolucizumab (6.0 mg/0.05 mL). Methods: All patients underwent indocyanine green angiography at both baseline and 3 months after initial injection and were followed up monthly with an as-needed regimen for up to 12 months. A total of 62 patients with PCV were included: 30 eyes were treated with brolucizumab, and 32 were treated with aflibercept. Eyes with complete regression of polyps (regression group) had significantly smaller maximum polyp diameter and were more frequently treated with brolucizumab than those without complete regression (non-regression) group. Results: Best corrected visual acuity was comparable between the two groups at 12 months. Although the 12-month retreatment-free proportion was comparable between the two groups (33.0% versus 27.0%, p = 0.59), a retreatment-free period was significantly longer in the regression group than in the non-regression group (8.3 ± 3.3 versus 6.5 ± 3.6 months, p = 0.022), and the number of additional injections was significantly fewer in the regression group than in the non-regression group (1.2 ± 1.2 versus 3.0 ± 2.6, p = 0.007). Conclusions: Complete regression of polyps observed after the initial phase possibly prolongs the retreatment-free period and reduces the number of additional injections irrespective of aflibercept or brolucizumab

2018ネンド トショカン ゲンバ エンシュウ ホウコク / <アイチケン トショカン> / <イバラキ シリツ チュウオウ トショカン> / <ウジシ チュウオウ トショカン> / <オオサカ シリツ チュウオウ トショカン> / <オオサカ フリツ ダンジョ キョウドウ サンカク セイショウネン センター ジョウホウ ライブラリー> / <オオサカ フリツ チュウオウ トショカン> / <オオサカ フリツ ナカノシマ トショカン> / <オオツ シリツ トショカン> / <キョウタナベ シリツ チュウオウ トショカン> / <キョウトシ ウキョウ チュウオウ トショカン> / <キョウトシ ダイゴ チュウオウ トショカン> / <キョウトシ フシミ チュウオウ トショカン> / <キョウト フリツ キョウトガク レキサイカン> / <キョウト フリツ トショカン> / <クマモト シリツ トショカン> / <コウベシ チュウオウ トショカン> / <コクサイ ニホン ブンカ ケンキュウ センター トショカン> / <コクリツ コッカイ トショカン トウキョウ ホンカン> / <ジョウヨウ シリツ トショカン> / <セタガヤ クリツ チュウオウ トショカン> / <タカツキ シリツ チュウオウ トショカン> / <ドウシシャ コウトウ ガッコウ トショカン> / <ドウシシャ ジョシ ダイガク トショ ジョウホウガク センター> / <ドウシシャ ジョシ チュウガッコウ コウトウ ガッコウ トショ ジョウホウ センター> / <ドウシシャ ダイガク トショカン> / <トヨナカ シリツ オカマチ トショカン> / <ナラ ケンリツ トショ ジョウホウカン> / <ニシノミヤ シリツ チュウオウ トショカン> / <ヒロシマ シリツ チュウオウ トショカン> / <ヒラカタ シリツ チュウオウ トショカン> / <ヤス トショカン> / <ヤワタ シリツ ヤワタ シミン トショカン>

application/pdfdepartmental bulletin pape

J.A.ホブスンと直接民主主義

2006-09-30This inquiry is an attempt to grasp the significance of democracy in J.A.Hobson's political thought. After the triumph of the 1906 election, the Liberal Government, pursuing a policy of social reform, was confronted with the obstructive action of the House of Lords, which, by wielding a veto, rejected or mutilated important Liberal measures passed by the House of Commons. Faced with the crisis of the Liberal Government, Hobson proposed to introduce the referendum into the English Constitution. His scheme of referendum was moulded upon that of Switzerland. The Swiss democracy was drawing the attention of Hobson and H.D.Lloyd, who had investigated the working of economic and political power of the American Trusts exercising absolute control over markets. For Switzerland, without carrying out a policy of territorial expansion, concentrated her energy on her internal resources, developed various institutions of direct democracy, and fastened a sense of responsibility upon the minds of the citizen-voters by stimulating their participation in the acts of government. Profoundly impressed by the lessons of the Swiss democracy, Hobson advocated the referendum to check abuses of the representative system by capitalist organizations and to give concrete expression to the popular will.departmental bulletin pape

地下空間 : 21世紀に向けて : 2.地下空間利用の歴史的背景

rights: 社団法人地盤工学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation: IsVersionOf: http://ci.nii.ac.jp/naid/110003967251/textapplication/pdfjournal articl

GPR17 is an essential regulator for the temporal adaptation of Sonic hedgehog signalling in neural tube development

Dorsal-ventral pattern formation of the neural tube is regulated by temporal and spatial activities of extracellular signalling molecules. Sonic hedgehog (Shh) assigns ventral neural subtypes via activation of the Gli transcription factors. Shh activity in the neural progenitor cells changes dynamically during differentiation, but the mechanisms regulating this dynamicity are not fully understood.Here we show that temporal change of the intracellular cAMP level confers the temporal Shh signal, and the purinergic-type G-protein coupled receptor GPR17 plays an essential role for this regulation. GPR17 is highly expressed in the ventral progenitor regions of the neural tube and acts as a negative regulator of the Shh signal in chick embryos. While the activation of the GPR17-related signal inhibits ventral identity, perturbation of GPR17 expression leads to aberrant expansion of ventral neural domains. Notably, perturbation of GPR17 expression partially inhibits the negative feedback of Gli activity. Moreover, GPR17 increases cAMP activity, suggesting that it exerts its function by inhibiting the processing of Gli3 protein. GPR17 also negatively regulates Shh signalling in neural cells differentiated from mouse embryonic stem cells, suggesting that GPR17 function is conserved among different organisms. Our results demonstrate that GPR17 is a novel negative regulator of Shh signalling in a wide range of cellular contexts.journal articl

Blood and Hair Manganese Concentrations in Pregnant Women from the Infants’ Environmental Health Study (ISA) in Costa Rica

Manganese (Mn), an essential nutrient, is a neurotoxicant at high concentrations. We measured Mn concentrations in repeated blood and hair samples collected from 449 pregnant women living near banana plantations with extensive aerial spraying of Mn-containing fungicide mancozeb in Costa Rica, and examined environmental and lifestyle factors associated with these biomarkers. Mean blood Mn and geometric mean hair Mn concentrations were 24.4 μg/L (8.9–56.3) and 1.8 μg/g (0.05–53.3), respectively. Blood Mn concentrations were positively associated with gestational age at sampling (β = 0.2; 95% CI: 0.1 to 0.2), number of household members (β = 0.4; 95% CI: 0.1 to 0.6), and living in a house made of permeable and difficult-to-clean materials (β = 2.6; 95% CI: 1.3 to 4.0); and inversely related to smoking (β = −3.1; 95% CI: −5.8 to −0.3). Hair Mn concentrations were inversely associated with gestational age at sampling (% change = 0.8; 95% CI: −1.6 to 0.0); and positively associated with living within 50 m of a plantation (% change = 42.1; 95% CI: 14.2 to 76.9) and Mn concentrations in drinking water (% change = 17.5; 95% CI: 12.2 to 22.8). Our findings suggest that pregnant women living near banana plantations aerially sprayed with mancozeb may be environmentally exposed to Mn

Clinical and genetic characteristics of simple central serous chorioretinopathy according to age

ABSTRACT Purpose To investigate whether genetic and clinical characteristics differ depending on generations using 326 patients (male/female, 259/67; mean age, 55.4 ± 12.5 years) with simple CSC. Methods All patients were diagnosed with simple CSC, defined as a retinal pigment epithelium alteration area equal to or smaller than 2-disc areas based on multimodal imaging at the initial presentation. We cross-sectionally evaluated clinical characteristics at the initial visit and genotyped CFH rs800292 and rs1329428 for all patients using TaqMan technology. Results As generations decreased, the proportion of males, subfoveal choroidal thickness, and prevalence of fibrin significantly increased (p < 0.001, p < 0.001, and p = 0.012, respectively), and the best-corrected visual acuity improved (p < 0.001); in contrast, the prevalence of pachydrusen significantly decreased (p < 0.001). The younger presentation was significantly associated with male and risk variants (T allele) of CFH rs1329428 (p = 9.1 × 10−7 and p = 0.042, respectively), and patients were estimated to present 2 years younger per one T allele of CFH rs1329428 (p = 0.042, β = −1.95, stepwise regression analysis). Conclusion Clinical and genetic characteristics differed significantly among patients with simple CSC, depending on their generation