SV2TTSによる感情音声合成を用いた感情認識

電気通信大学修士2022近年,超高齢化社会を迎えた日本では,認知症患者に対する介護の需要が急速に増加しており、現場で働く介護士たちの負担も同じく増加している。認知症患者の認知機能の低下により暴言・暴力の増加、徘徊などのBPSDと呼ばれる併発症は対応する介護者の心身疲労につながりやすく、早期発見し適切に対応することが求められる。このようなBPSDの発症を予測するためには、声による感情変化の予測が極めて重要である。しかし、認知症患者の音声による感情認識器を作成するためには、感情付き音声の大量収集が必要であるが、感情を含んだ音声を認知症患者から集めることは，プライバシーの問題や指導の困難さの観点から非常に困難である。 本研究では、SV2TTSを用いて少量のデータから（Zero shot）認知症患者の音声の特徴を求め、その特徴から大量の感情付き音声データを生成するモデルを構築し、そのモデルから生成した音声から感情認識用モデルを作成し，認知症患者の音声の感情予測の可能性を検討する。本研究ではSV2TTSモデルをもとに感情符号化法を適用することで、感情モデルの訓練を行い、感情付き音声合成を行った。認知症患者感情音声のシミュレーションデータセットを作成し、環境音認識モデルに感情音声のラベルを追加して音声認識モデルの訓練を行った。認識精度は18%に達したが、今後も続くプロジェクトの前段階として、感情音声合成・認識の課題を明らかにできた。thesi

コーポレート・ガバナンス，企業価値から顧客価値へ《特別寄稿》

はじめに 1．企業価値とは，そしてその流行の問題点 2．企業価値評価とは―将来キャッシュ・フローの割引現在価値の構造，でも思い通りにならない 3．企業価値評価の問題点―将来期待はどうしたら測れるのか 4．真の企業価値は何か―貸借対照表左側「顧客価値」に意義ありtextapplication/pdfdepartmental bulletin pape

Observation of a Resonancelike Structure in the π^+-Ψ' Mass Distribution in Exclusive B → Kπ^+-Ψ' Decays

A distinct peak is observed in the π^±Ψ'invariant mass distribution near 4.43 GeV in B→ Kπ^±Ψ' decays. A fit using a Breit-Wigner resonance shape yields a peak mass and width of M = 4433± 4(stat)± 2(syst) MeV and Γ= 45\begin+18\-13\end(stat)\begin+30\-13\end(syst)MeV.The product branching fraction is determined to be B(B^0→ K^∓Z^±(4430)→ π^±Ψ')= (4.1±1.0(stat)±1.4(syst))×10^{-5}, where Z^±(4430)is used to denote the observed structure. The statistical significance of the observed peak is 6.5σ. These results are obtained from a 605 fb^{-1} data sample that contains 657 ×10^6 B\bar{B} pairs collected near the Υ(4S) resonance with the Belle detector at the KEKB asymmetric energy e^+e^- collider.journal articl

Search for CP Violation in the Decay B0→D*±D∓

journal articl

Correlation between match to optimal σ promoter (−35 and −10 sequences) measured by the pftools 2

<p><b>Copyright information:</b></p><p>Taken from "Detection of low-level promoter activity within open reading frame sequences of "</p><p>Nucleic Acids Research 2005;33(19):6268-6276.</p><p>Published online 31 Oct 2005</p><p>PMCID:PMC1275588.</p><p>© The Author 2005. Published by Oxford University Press. All rights reserved</p>2 program (homology score, ) and log of the promoter (β-galactosidase, ) activity. The regression line for the 39 randomly isolated promoters that have homology scores of 45 or greater (open circles) has the formula = −5.5496 + 0.14772 and an of 0.417. Two SDs are indicated by the dashed lines. The eight inserts selected on the basis of high activity are shown by filled circles

The distribution of promoter (β-galactosidase) activities of 105 random fragments of as assayed in the promoterless tester plasmid, pRS551

<p><b>Copyright information:</b></p><p>Taken from "Detection of low-level promoter activity within open reading frame sequences of "</p><p>Nucleic Acids Research 2005;33(19):6268-6276.</p><p>Published online 31 Oct 2005</p><p>PMCID:PMC1275588.</p><p>© The Author 2005. Published by Oxford University Press. All rights reserved</p> We defined a sequence as having potential promoter activity when the β-galactosidase activity of the strain was increased by 3-fold or more over that of the strain with the parental plasmid pRS551 (i.e. to >10 MU). We found that 56 (53%) of the inserts (tested in only one orientation) exhibited promoter activity by this criterion. However, some of the inserts may contain more than one promoter. Applying the Poisson distibution, (0) = e, where (0) is the probability of finding no activity (i.e. the null class of plasmids expressing 0–10 MU = 47%), and solving for λ (the average number of potential promoters per insert), we calculate there are on average 0.76 promoters per fragment (in one of the two possible orientations). We therefore conclude that there are ∼1.52 (twice 0.76) promoters per 163 bp or one full promoter in either direction per ∼107 bp

TolC, EmrB, and MdtB are required for extreme-acid survival.

<p>Strains W3110 (K-12 parent strain), JLS1015 (W3110 <i>tolC</i>::<i>kan</i>), JLS1027 (W3110 <i>emrB</i>::<i>kan</i>), and JLS1024 (<i>mdtB</i>::<i>kan</i>) were diluted into LBK pH 2 and exposed with rotation for 2 hours at 37°C after overnight growth to stationary phase in buffered LBK at <b>A</b>) pH 7.0 for non-acid-adapted cells and <b>B</b>) pH 5.5 for acid-adapted cells. Error bars = SEM, n = 6. *Below the level of detection.</p

<i>E. coli</i> K-12 strains and plasmids used in this study.

<p><i>E. coli</i> K-12 strains and plasmids used in this study.</p

TolC is required for extreme-acid survival in a strain defective for eight MDR efflux inner membrane pumps.

<p>Strains N7829 (K-12 derivative), M5567 (N7829 <i>tolC</i>::<i>kan</i>), M6293 (N7829 <i>acrB</i>::<i>frt acrD</i>::<i>frt emrB</i>::<i>frt emrY</i>::<i>frt macB</i>::<i>frt mdtC</i>::<i>frt mdtF</i>::<i>frt acrEF</i>::<i>spc</i>), and JLS1042 (M6293 <i>tolC</i>::<i>kan</i>) were grown overnight to stationary phase in LBK buffered at pH 5.5 (100 mM MES), diluted into LBK pH 2, and exposed for 2 hours at 37°C. Grey bars represent the parent strain listed with the additional kanamycin resistance insertion in <i>tolC</i>. Error bars = SEM, n = 6.</p

TolC is required for expression of the glutamate-dependent acid resistance system.

<p><i>E. coli</i> wild-type MG1655 and its TolC-deficient derivative MG1655T (<i>tolC</i>::Tn<i>10</i>) were assayed for glutamate decarboxylase activity, <i>gadA</i> mRNA expression, and GadA/B expression. <b>A</b>) Both strains were tested for glutamate decarboxylase activity at pH 7.5 and pH 5.5 using the GAD reagent as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018960#s4" target="_blank">Materials and Methods</a>. The pH indicator dye bromocresol green changes from yellow to blue when L-glutamic acid is decarboxylated. There was almost no change in color with the <i>tolC</i>::Tn<i>10</i> strain at pH 5.5. <b>B</b>) Northern analysis of <i>gadA</i> and <i>cadA</i> mRNA at pH 7.5 and pH 5.5 with the wild-type and <i>tolC</i>::Tn<i>10</i> strains; 16S rRNA bands are provided as a control. <b>C</b>) A 53 kDa protein band (indicated by an arrow) was observed by SDS-PAGE only in wild-type cultures at pH 5.5; this band was identified as a mixture of GadA and GadB proteins by mass spectrometry analysis (MALDI-TOF).</p