22 research outputs found
〈Book Review〉 "A study of Tales on Dreams Collected in Uji Shūi monogatari" by Jiyoung Cho
application/pdf日本韓国研究. 2021, 1, P.116-118journal articl
研究速報 : 揮発性有機化合物の拡散・吸脱着等のモデリングとその数値予測に関する研究 : 室内濃度分布計算における吸脱着面のモデル化と数値解析
departmental bulletin pape
Additional file 2: of Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers
Table S1. Epitope mapping of HER3-VIA using spotted 15-mer peptide arrays. Epitope mapping was performed using spotted peptide arrays of 15-mer peptides overlapping by four amino acids representing the full length of the human HER3 protein. HER3 peptides were coated onto cellulose membranes using a Spot Robot ASP 222 (AbiMed) and epitope mapping of HER3-VIA (1:100 dilution in saline) was performed as described [26]. (PDF 36 kb
Near-infrared Colorized Imaging Technologies and Their Fundus Camera Applications
This study proposes to adapt the fundus camera for use as a personal healthcare tool. The proposed system uses near-infrared light to avoid blinding the subject and three-wavelength near-infrared imaging to acquire colorized fundus images. First, the optical system with the fundus camera was tested using a three-plate near-infrared snapshot camera. Subsequently, image processing and denoising techniques, including tracking and image integration, were applied to reduce the blur caused by biological scattering. Furthermore, a singlechip three-wavelength near-infrared-compatible image sensor is required for device miniaturization, for which a dielectric multilayer Fabry-Perot bandpass filter was adopted as its transmission wavelength can be easily controlled. In this study, the optical design of the dielectric multilayer structure, the fabrication process of the mosaic filter, and the chip mounting technology are investigated. The demosaicing process and color space conversion corresponding to the spectral response characteristics of the fabricated image sensor are also discussed.journal articl
Additional file 3: of Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers
Figure S2. Flow cytometric detection of cell surface EGFR/HER2/HER3 expression after treatment with HER3-VIA, trastuzumab, cetuximab and lapatinib. To assess the internalization of EGFR family receptors, SKBR3 cells, positive for EGFR/HER2/HER3, were incubated with HER3-VIA, GFP-VIA (1:100 dilution), trastuzumab (1 μM), cetuximab (1 μM), or lapatinib (1 μM) for 3 h or 24 h. Cells were harvested using cell-dissociation buffer and stained with PE-conjugated anti-EGFP (clone 5E10D3, Novus Biologicals), anti-HER2 (clone Neu 24.7, BD Bioscience) or anti-HER3 antibody (Clone 1B4C3, BioLegend) and acquired by LSRII flow cytometer. Isotype control mouse IgG was used as negative control staining and is shown as filled gray histograms. Experiments were performed four times for EGFR expression analysis and twice for HER2 and HER3, and representative histograms are shown. Median fluorescence intensities (MFIs) of reagent-treated cells were compared to untreated control cells and ratios (MFI of treated/MFI of untreated) were calculated in each experiment. The averages of ratios are shown in each histogram. (PDF 732 kb
Supplementary Figure 3 from Preclinical Activity Profile and Therapeutic Efficacy of the HSP90 Inhibitor Ganetespib in Triple-Negative Breast Cancer
PDF file - 2583K, DNA damage and cell cycle distribution following combination ganetespib + doxorubicin treatment.</p
Supplementary Methods, Figure Legend from Preclinical Activity Profile and Therapeutic Efficacy of the HSP90 Inhibitor Ganetespib in Triple-Negative Breast Cancer
PDF file - 62K</p
