Beyond Vygotsky ?

departmental bulletin pape

Observation of B̅0→D(*)0pp̅

journal articl

Asymptotic behavior of solutions of Black-Scholes type equations based on weakly dependent random variables

departmental bulletin pape

高出力パワーアシスト装置による物体運搬の重量知覚特性解析に関する研究

application/pdf三重大学大学院 工学研究科 機械工学専攻 システム設計研究室62pthesi

ヘーゲル論理学批判序説 (I)

application/pdfNach der Zeit von Hegel ist ed die Aufgabe der Philosophie, die Hegelsche Philosophie zu begreifen und zu kritisieren. Der Kern der Hegelschen Philosophie besteht in der Begriffslehre von seiner "Logik", also muss sie begriffen und kritisiert werden. Wir konnen den Prozess der Vollendung oder Reifung der burgerlichen Gesellschaft in Japan heute und den Prozess der Kritik am negativen Zusammenhang zwischen Sozischen Philosophie zusammenfassen. Dabei handelt es sich um Allgemeinheit, Besonderheit und Einzelheit.departmental bulletin pape

養護 子どもの心が動く健康教育をめざして : 医療保健格差から考える(Ⅶ. 教科研究)

2010-01-25生徒が地球の一市民であるという自覚の元に持続可能な健康的な生活を送るためには、個人の実践力だけでなく、共に関わりあい、平和に暮らしていこうという視点も重要である。そこで、高校２年生の学校設定科目で、医療保健格差から考える授業実践を行った。また、ネパールでの医療保健の現状を参考に教材開発を試みた。多様な視点から健康教育を実践していく意義は大変大きいと考えている。departmental bulletin pape

Tuberculin-Specific T Cells Are Reduced in Active Pulmonary Tuberculosis Compared to LTBI or Status Post BCG Vaccination

Functional characteristics of tuberculosis (TB)-specific CD4 T cells were studied in clinically active pulmonary TB (n = 21) and high TB exposure including LTBI (n = 17). Following tuberculin stimulation, activated CD4 T cells were identified by flow-cytometry (CD154 up-regulation, degranulation, interferon gamma [IFN-gamma], tumor necrosis factor alpha [TNF-alpha], and interleukin 2 [IL-2\ production). Interestingly, CD154 up-regulation accounted for similar to 80% of activated CD4 T cells in the active TB group but just 40% in the controls, whereas IFN-gamma accounted for only similar to 50% of activated cells in each group. The frequencies of CD4 T cells displaying at least 1 activation marker discriminated better between the groups than those displaying degranulation or IFN-gamma production alone

Loss of CD27 on tuberculin-reactive CD4 T-cells identifies smear and/or culture positive TB.

<p>A: Patients with smear and/or culture positive pulmonary TB were distinguishable from those with smear and culture negative pulmonary TB using a threshold of 48% (dotted line). Patients more than 1 year after beginning of treatment mostly had values >48% if TB was initially smear positive (empty squares), and <48%, if TB was smear negative (filled squares). Statistically significant differences are indicated (Chi-square test). Primary end-point was the percentage of CD27-negative cells among reactive cells. Vertical numbers indicate the number of evaluated events (median and range). B: Loss of CD27 expression on tuberculin and ESAT-6 specific CD4 T-cells is closely correlated.</p

Flow diagram of the blind prospective diagnostic study.

<p>Eligible patients were recruited by the admitting physician. Diagnostic standard refers to the standard diagnostic procedure for TB in this hospital including history, X-ray, sputum microscopy and culture, PCR, biopsy and histology where applicable. TST = tuberculin skin test</p

CD27 expression on tuberculin-reactive CD4 T-cells reverts very slowly .

<p>A: CD27-expression on tuberculin-reactive CD4 T-cells was plotted against the length of the interval between the collection date of the analyzed blood sample and the collection date of the last positive sputum sample (all data from blinded study). Negative values indicate that sputum was already smear and culture negative when tuberculin-reactive CD4 T-cells were analyzed, positive values indicate that sputum samples were still positive and remained so for the indicated time. B: serial measurements in 7 individuals (data analysis blinded).</p