山东方言的文化特征及其演变 : 与小木裕文先生对谈

departmental bulletin pape

Beyond Vygotsky ?

departmental bulletin pape

Observation of B̅0→D(*)0pp̅

journal articl

Completely integrable inplicit ordinary differential equations

departmental bulletin pape

Chromatin structure and transcriptional regulation in arabidopsis

奈良先端科学技術大学院大学博士(バイオサイエンス)doctoral thesi

英語 シャドーイングからセルフトーク・ミラーリングへの段階的指導方法の開発(IX. 教科研究)

2010-01-25英語初・中級レベルの中高生の授業で、テキストreadingにoutput志向のshadowing＆self-talk法を取り入れることで、英語理解力が高めることができる。この方法はコミュニケーション重視の時代の授業外での自立的な学習方法としても有効である。departmental bulletin pape

Loss of CD27 on tuberculin-reactive CD4 T-cells identifies smear and/or culture positive TB.

<p>A: Patients with smear and/or culture positive pulmonary TB were distinguishable from those with smear and culture negative pulmonary TB using a threshold of 48% (dotted line). Patients more than 1 year after beginning of treatment mostly had values >48% if TB was initially smear positive (empty squares), and <48%, if TB was smear negative (filled squares). Statistically significant differences are indicated (Chi-square test). Primary end-point was the percentage of CD27-negative cells among reactive cells. Vertical numbers indicate the number of evaluated events (median and range). B: Loss of CD27 expression on tuberculin and ESAT-6 specific CD4 T-cells is closely correlated.</p

Flow diagram of the blind prospective diagnostic study.

<p>Eligible patients were recruited by the admitting physician. Diagnostic standard refers to the standard diagnostic procedure for TB in this hospital including history, X-ray, sputum microscopy and culture, PCR, biopsy and histology where applicable. TST = tuberculin skin test</p

Distribution of tuberculin-reactive CD4 T-cells among the subsets defined by classic memory/naïve markers.

<p>PBMC were stained with the indicated monoclonal antibodies. Panel A shows CD3 T-cells, panels B-D only CD4 T-cells. IFN-γ-producing ex-vivo tuberculin-reactive events are highlighted black. The dotted horizontal line in B shows the limit set for CD27-positivity. Representative results from one patient with active TB are shown.</p

CD27 expression on tuberculin-reactive CD4 T-cells reverts very slowly .

<p>A: CD27-expression on tuberculin-reactive CD4 T-cells was plotted against the length of the interval between the collection date of the analyzed blood sample and the collection date of the last positive sputum sample (all data from blinded study). Negative values indicate that sputum was already smear and culture negative when tuberculin-reactive CD4 T-cells were analyzed, positive values indicate that sputum samples were still positive and remained so for the indicated time. B: serial measurements in 7 individuals (data analysis blinded).</p