11 research outputs found
Chip Formation Behaviour in Ultra-Precision Cutting of Electroless Nickel Plated mold Substrates
journal articl
High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies-0
Ces in the melting of all the other samples are plotted relative to this baseline. : A difference plot of exon 19 using different amounts of template from one sample. Different amounts of template, ranging from 1 ng to 100 ng, were assessed by the exon 19 assay using a sample with a p.E746_A750 deletion mutation. A near identical heteroduplex type melting pattern is observed from each amount of template tested. The wild-type control sample is shown as a horizontal line (in blue). : A difference plot of exon 19 using different samples with different amounts of template. Each sample contained the same p.E746_A750 in-frame deletion mutation but the samples were at different DNA concentrations and from different individuals. A wild-type control sample is shown as a horizontal line (in blue). All samples show different melting patterns compared to the wild-type.<p><b>Copyright information:</b></p><p>Taken from "High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies"</p><p>http://www.biomedcentral.com/1471-2407/8/142</p><p>BMC Cancer 2008;8():142-142.</p><p>Published online 21 May 2008</p><p>PMCID:PMC2408599.</p><p></p
High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies-2
and TX440 in orange). : A p.S768I in TX53, a p.H773_R776insYNPY in TX383 and a p.D770_H773insGSVD in TX440 mutation are detected by sequencing from the HRM positive samples. : The difference plot of HRM exon 21 shows three HRM positive samples (TX23 in red, TX44 in purple and TX324 in orange). : Sequencing chromatograms show a p.R836R SNP in TX23, a p.R836C in TX44 and a p.L858R mutation in TX324.<p><b>Copyright information:</b></p><p>Taken from "High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies"</p><p>http://www.biomedcentral.com/1471-2407/8/142</p><p>BMC Cancer 2008;8():142-142.</p><p>Published online 21 May 2008</p><p>PMCID:PMC2408599.</p><p></p
High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies-1
In red). : Sequencing chromatograms show a p.E709A in TX36, a p.G719S in TX53 and a p.E709_T710delinsD in TX290. : The difference plot of EGFR exon 19 shows melting profiles for three positive samples (TX127 in brown, TX142 in red and TX186 in orange). : Sequencing chromatograms show a p.L747_P753delinsS in TX127, a p.E746_A750del in TX142 and a p.E746_A750delinsF mutation in TX186.<p><b>Copyright information:</b></p><p>Taken from "High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies"</p><p>http://www.biomedcentral.com/1471-2407/8/142</p><p>BMC Cancer 2008;8():142-142.</p><p>Published online 21 May 2008</p><p>PMCID:PMC2408599.</p><p></p
High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies-3
D TX64 in brown) and a positive mutation control (RPMI8226 in red) were compared to a wild-type sample. The wild-type control sample is shown as a horizontal line in blue. Four patients and the positive control samples had different melting profiles compared to the wild-type. Sequencing of the patients revealed four different amino acid changes at codon 12; p.G12D in TX23, p.G12F in TX41, p.G12V in TX55 and p.G12C in TX64.<p><b>Copyright information:</b></p><p>Taken from "High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies"</p><p>http://www.biomedcentral.com/1471-2407/8/142</p><p>BMC Cancer 2008;8():142-142.</p><p>Published online 21 May 2008</p><p>PMCID:PMC2408599.</p><p></p
Supplementary Table 1. Variants detected and variant allele frequencies in FFPE tumor samples following parallel off-bead or on-bead pre-capture library generation.
Supplemental Table
1. Variants detected and variant allele frequencies in FFPE tumor samples
following parallel off-bead or on-bead pre-capture library generation.
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Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer-2
<p><b>Copyright information:</b></p><p>Taken from "Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer"</p><p>http://breast-cancer-research.com/content/9/6/R89</p><p>Breast Cancer Research : BCR 2007;9(6):R89-R89.</p><p>Published online 20 Dec 2007</p><p>PMCID:PMC2246192.</p><p></p
Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer-0
<p><b>Copyright information:</b></p><p>Taken from "Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer"</p><p>http://breast-cancer-research.com/content/9/6/R89</p><p>Breast Cancer Research : BCR 2007;9(6):R89-R89.</p><p>Published online 20 Dec 2007</p><p>PMCID:PMC2246192.</p><p></p
