Effects of Washcoat on Initial PM Filtration Efficiency and Pressure Drop in SiC DPF

The washcoat (W/C) on a catalytic diesel particulate filter (DPF) greatly alters the pore structure and wall surface condition of the original substrate of DPF, which then affects the filtration efficiency and pressure drop behavior. In the present study, we examined this W/C effect on the initial PM filtration efficiency and pressure loss by changing amounts of washcoat on a SiC-DPF. We measured particle number concentration and particle size distribution in the diesel exhaust gas downstream of the DPF by EEPS. High filtration efficiency was achieved quickly when the W/C amount was increased. We introduced new parameters, T90 and T99, which were the filtration efficiencies that reach more than 90% and 99%, respectively, of the initial DPF usage. The PM trapping mechanisms could be classified according to the PM size. Trapping of PM whose diameter is smaller than 30 nm is little affected by the W/C. However, for PM over 30 nm, as amounts of W/C are increased, particle number concentration decreases rapidly and less PM leakage is observed for the initial filtration process. On the other hand, the initial backpressure and the backpressure during soot loading increased in accordance with W/C amount. Since the relationship between the filtration efficiency and the pressure loss has a trade-off, it is important to design DPF by considering W/C effects.Technical Papers presented at SAE 2011 World Congress & Exhibitionresearch repor

我国における乳児栄養法の変遷

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Ritsumeikan Asia Pacific University Opening in April 2000*

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構造機能相関研究への応用のための生理活性ペプチドの化学合成とその性質に関する研究

Thesisthesi

Two Cases of Benign Liver Cysts with Elevated Concentrations of CA19-9 in Cystic Fluid

Two cases of benign cysts of the liver with a high concentration of CA19-9 in the cystic fluid are presented. Both patients complained of slight abdominal distension. Ultrasonography (US) and computed tomography (CT) revealed large cystic mass lesions in the liver. Serous fluid without atypical cells was obtained by percutaneous needle aspiration of the cysts; both cases had a high concentration of CA19-9 in the cystic fluid. Although both patients were treated by ethanol injection through the drainage tube into the cystic cavity, surgery was also required in one case. Positive immunohistochemical staining for CA19-9 was observed in the cytoplasm of the epithelial cells of the cyst wall in the surgical case. These results suggest that the high concentration of CA19-9 in the cystic fluid was due to the secretion from epithelial cells.departmental bulletin pape

Supplemental Figure S3 from Detection of Tumor Suppressor Genes in Cancer Development by a Novel shRNA-Based Method

Supplemental Figure S3: shRNA mediated silencing of p16Ink4a or Trp53 leads to decreased survival. Kaplan-Meier survival analysis shows a significant decrease in survival of animals that were injected with Kras-shRNAp16Ink4a-PDCs (median survival 109 days, p=0.04) or Kras-shRNA-Trp53-PDCs (median survival 125.5 days, p=0.038)</p

Supplemental Figure S1 from Detection of Tumor Suppressor Genes in Cancer Development by a Novel shRNA-Based Method

Supplemental Figure S1: Lentiviral transduction of Kras-PDCs in vitro induces sustained loss of target gene protein expression in vivo. Primary tumors derived from Kras-shRNAp16Ink4a-PDCs or Kras-shRNATrp53-PDCs stained negative for P16INK4a and TRP53, respectively. Tissues containing PanINs derived form Ptf1a-Cre;LSL-KrasG12D served as positive controls.</p

Supplemental figure S2 from Detection of Tumor Suppressor Genes in Cancer Development by a Novel shRNA-Based Method

Supplemental Figure S2: shRNA mediated loss of tumor suppressor genes results in liver metastasis. Histology shows microscopic liver metastasis that developed in animals that received Kras-shRNAp16Ink4a #2-PDCs or Kras-shRNATrp53-PDCs. Of note animals that were implanted with Kras-shRNAp16Ink4a #1-PDCs did not develop liver metastasis.</p

Activity and complex formation of Taspase1 and catalytically inactive mutants. A.

<p>Taspase1 processing of AF4<b>•</b>MLL substrates in leukemic cells. Co-transfection of Tasp-GFP resulted in proteolytic cleavage and nuclear accumulation of the red fluorescent biosensor, A<b>•</b>M_S2_R, in K562 cells. In contrast, co-expression of Tasp^D233A-GFP leads to partial processing and nuclear translocation, while Tasp^T234V-GFP was completely inactive. Localization was analyzed 24 h post transfection. GFP/mCherry were visualized by fluorescence microscopy. Scale bars, 10 µm. <b>B.</b> Processing of AF4<b>•</b>MLL substrates. Co-transfection of Tasp resulted in proteolytic cleavage of the biosensor A<b>•</b>M_S2_R in 293T cells as indicated by immunoblot. In contrast, Tasp^T234V was inactive in <i>cis</i> and <i>trans</i>. Proteins were visualized using α-GST or α-Taspase1 Abs. GapDH served as loading control. fl, unprocessed Taspase1; Tasp_β, Taspase1 β-subunit.</p

Cell cycle arrest by siRNA.

<p><b>A)</b> Cells were transfected without siRNA, with scramble siRNA (scramb) or with siRNA against cyclin D1 or cyclin-kinase (CDK4). Forty-eight hours post-transfection cells were infected with VSV-wt at an MOI of 0.1 for 24 hours. Results show the average of at least three independent experiments. <b>B)</b> Mock-infected lysates from PH5CH8 and Huh-7 cells of the experiment describe above are shown for the expression of cyclin D1 and CDK4. <b>C)</b> FACS analysis of cell cycle arrest in Huh-7 cells upon treatment with siRNA targeting CDK4 and cyclin D1 or control siRNA (SCR). Experiments were conducted at least three times and triplicate values of one experiment are shown as representative (p<0.001).</p