THE RELATIONSHIP BETWEEN DIMENSIONS OF EXECUTIVE FUNCTIONING AND RUMINATION IN YOUTH: A LONGITUDINAL AND BIDIRECTIONAL STUDY

Extensive work has examined the relationship between rumination and executive functioning (EF) mainly in adult samples, lending support for theory that rumination is characterized by poorer shifting, inhibition, and/or working memory updating abilities. However, literature on the relationship between rumination and EF in youth is more equivocal. Further, the directionality of this relationship is somewhat unclear, and may differ as a function of EF type. The present study conducted a longitudinal, bidirectional examination of the relationship between rumination on both negative and positive affect and several types of EF in a sample of 175 youth (aged 9-13) at baseline, 9-month, and 18-month follow-up assessments. Although rumination was not associated with shifting, inhibition, and/or working memory, support generally emerged for significant concurrent relationships between rumination and greater problems with inhibition, planning/organization, and monitoring. There was minimal support for significant longitudinal relationships between rumination and EF, and no evidence emerged for relationships between rumination on positive affect and EF. The present study provides some support for a “common cause” model of the relationship between rumination and EF (e.g., depressive symptoms; shared neurobiological dysfunction), although more research is needed to examine longitudinal relationships between these constructs.Psycholog

カ･デ･ウシンスキー(1824-1870)-書誌学的考察3-

Articledepartmental bulletin pape

Hemokinin-1 mediates pruriceptive processing in the rat spinal cord

宮崎大学博士(医学)2014年度doctoral thesi

地域の医療情報を集約化することで視えること・出来ること −医療提供体制の再編に向けて−

定例会・研修会articl

Application of Family Collaborative Participatory Practice: A Trial of Family Participatory Service Planning Program Adopted FGC in the field of Eldery Care.

2008(平成20)～2009(平成21)年度プロジェクト研究報告書わが国の家族支援におけるファミリーグループカンファレンス導入の可能性Report of the Research Project: The Years. of 2008/2009Possibility of the Family Group Conference Introduction in the Japanese Family Supportdepartmental bulletin pape

ジドウ ノ ノウドウテキ ニ キク チカラ ノ イクセイ ニ キノウ スル カイテイ ト ソレニ モトズク ジッセン

departmental bulletin pape

Steps and Specific Cases to Functions to the Development of Active Listening Ability -For Elementary School students-

本研究では，児童の聴くことの課題を踏まえ，能動的に聴く力を育成するために，聴くことの階梯とそれに基づく実践が必要と考えた。そこで，児童が「自身の聴き方」を自覚し，新たな聴き方を他者と共に探究しながら獲得することにつながる階梯と具体事例について追究した。その過程で，児童は「自身の聴き方」に対して無自覚であることや，自身の考えを伝えることに意識が集中し，「他者の聴き方」の特性を見出すことに意識が向かないことが分かった。 今後，客観的に他者の聴き方を捉える手がかりを児童と共有する学習やツールの開発，教師が意図的に児童の聴く姿を価値づけることが必要である。また，本研究で導出した「児童の聴き方自覚を促すチェックリスト」の児童の自己評価を基に，児童個別の聴き方カルテを作成し，児童一人一人の聴く実態に応じた教育実践につなげていきたい。departmental bulletin pape

Bone marrow-derived mononuclear cells ameliorate neurological function in chronic cerebral infarction model mice via improvement of cerebral blood flow

Background aims: Stroke is a frequently observed neurological disorder that might lead to permanent and severe disability. Recently, various regenerative therapies have been developed, some of which have already been applied clinically. However, their outcomes have not been fully satisfactory. In particular, the development of regenerative therapies for chronic ischemic stroke is greatly needed. Herein intracerebral administration of bone marrow-derived mononuclear cells (BM-MNCs) was assessed as a potential treatment for chronic ischemic stroke using a severe combined immunodeficiency mouse model characterized by minimal vascular variation unrelated to immunodeficiency. Methods: A reproducible model of permanent middle cerebral artery occlusion was prepared, and intracerebral BM-MNC transplantation was performed 14 days after stroke induction in the infarcted brain. Results: Sensorimotor behavioral function and cerebral blood flow were significantly improved upon treatment with BM-MNCs compared to control medium injection. The transplanted cells exhibited characteristics of the vascular endothelium and microglia/macrophages. Significant angiogenesis and suppression of astrogliosis and microgliosis were observed in the affected brain. Messenger RNA expression analysis showed significant increases in anti-inflammatory cytokines, A2 astrocyte/anti-inflammatory microglia markers and vascular endothelial markers such as vascular endothelial growth factor and significant decreases in pro-inflammatory cytokines and A1 astrocyte/pro-inflammatory microglia markers following BM-MNC transplantation. Conclusions: These results suggest that intracerebral administration of BM-MNCs should be considered an effective cell therapy for chronic stroke.journal articl

呼吸・光合成量測定のための簡易装置の開発

text紀要論文 / Departmental Bulletin Paperdepartmental bulletin pape

Evaluation of the Ability to Form Biofilms in KPC-Producing and ESBL-Producing Klebsiella pneumoniae Isolated from Clinical Samples

The appearance of Klebsiella pneumoniae strains producing extended-spectrum β-lactamase (ESBL), and carbapenemase (KPC) has turned into a significant public health issue. ESBL- and KPC-producing K. pneumoniae’s ability to form biofilms is a significant concern as it can promote the spread of antibiotic resistance and prolong infections in healthcare facilities. A total of 45 K. pneumoniae strains were isolated from human infections. Antibiograms were performed for 17 antibiotics, ESBL production was tested by Etest ESBL PM/PML, a rapid test was used to detect KPC carbapenemases, and resistance genes were detected by PCR. Biofilm production was detected by the microtiter plate method. A total of 73% of multidrug resistance was found, with the highest resistance rates to ampicillin, trimethoprim–sulfamethoxazole, cefotaxime, amoxicillin-clavulanic acid, and aztreonam. Simultaneously, the most effective antibiotics were tetracycline and amikacin. blaCTX-M, blaTEM, blaSHV, aac(3)-II, aadA1, tetA, cmlA, catA, gyrA, gyrB, parC, sul1, sul2, sul3, blaKPC, blaOXA, and blaPER genes were detected. Biofilm production showed that 80% of K. pneumoniae strains were biofilm producers. Most ESBL- and KPC-producing isolates were weak biofilm producers (40.0% and 60.0%, respectively). There was no correlation between the ability to form stronger biofilms and the presence of ESBL and KPC enzymes in K. pneumoniae isolates