150 research outputs found

    The Camino de Santiago de Compostesa (Spain) and the Via Francigena (Italy); a comparison between two important historic pilgrimage routes in Europe

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    La ricerca mette a confronto due tra i principali cammini di fede della cristianit\ue0, il Cammino di Santiago di Compostela e la Via Francigena, analizzandone i fattori di successo e i punti di forza e di debolezza alla luce della loro pi\uf9 recente evoluzione

    Effects of sodium hyaluronate on experimental osteoarthritis in rabbit knee joints

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    1999-11The aim of this study was to examine the effects of intraarticular administration of hyaluronan (HA) on cartilage degradation. Using a partial menisectomy model of osteoarthritis (OA) in the rabbit knee, the authors investigated the catabolic and anabolic changes induced by intraarticular injection of HA. To analyze anabolic changes, the authors assessed cell proliferation by measuring [3H] thymidine uptake, and proteoglycan biosynthesis by noting [35S] sulfate incorporation. For catabolic changes, messenger ribonucleic acid (mRNA) expression of interstitial collagenase (MMP-1), stromelysin-1 (MMP-3), and tissue inhibitor of metalloproteinase-1 (TIMP-1) in cartilage and synovium were detected with reverse transcriptase polymerase chain reaction (RT-PCR). Of significance for blocking the development of early OA in chondrocytes was the finding that total proteoglycan synthesis in the HA treatment group was significantly higher than in the controls. At the mRNA level in cartilage and synovium, HA inhibited MMP-3 and TIMP-1 production in the same way in the HA treatment group, while not affecting MMP-1 production. Thus it can be concluded that HA affects cartilage catabolism and anabolism to prevent the progress of OA.departmental bulletin pape

    河野洋平邸黒曜石岩塊の移設-2008年度寄贈資料-

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    Articledepartmental bulletin pape

    Improved measurements of branching fractions and CP partial rate asymmetries for B-->omegaK and B-->omegapi

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    journal articl

    Clinical features of Maternal floor infarction (MFI)

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    Maternal floor infarction (MFI) は比較的まれな胎盤異常であり、胎児発育不全 (FGR) や子宮内胎児死亡の原因の一つとされる。今回当科で診断されたMFI 3症例の臨床像について検討した。 平均年齢は37歳で、膠原病や自己免疫性疾患の合併例は無かった。全例自然妊娠で、2例が妊娠高血圧症候群を合併した。全例に-2.0〜-3.0SDのFGRを伴い、うち1例は妊娠中期からの発症であった。2例に超音波Doppler検査において臍帯血流異常所見を認め、分娩時には胎児心拍数陣痛図でレベル3以上の異常所見が認められた。分娩様式は全例が緊急帝王切開であった。児は全例新生児集中治療室入院となり、予後からは1例で発達遅滞及び自閉傾向を認めた。Maternal floor infarction (MFI) is a relatively rare form of placental abnormality and is one of the known causes of fetal growth restriction (FGR) and intrauterine fetal death (IUFD). We report three cases of MFI that were diagnosed in our department. The average age of the patients was 37, and none of them had connective tissue or autoimmune disorders. All patients became pregnant through spontaneous conception, and two developed hypertensive disorders of pregnancy. All patients had FGR in the range of -2.0 to - 3.0 SD, and one developed FGR during the second trimester. Doppler ultrasound revealed abnormal umbilical blood flow in two of the patients, and cardiotocography revealed abnormalities of the fetal heartbeat (≥ level 3) during labor. All patients underwent emergency C-section. All newborns were subsequently admitted to our neonatal intensive care unit. Developmental delay and autistic features were observed in one of the newborns during follow-up.journal articl
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