Osteocondritis disecante de la cabeza del 2º metacarpiano en un niño: a propósito de un caso

La osteocondritis disecante en articulaciones de la mano es un proceso muy raro, sólo existen dos casos previos publicados en la literatura. Presentamos un paciente de 10 años de edad con dolor e impotencia funcional de la articulación metacarpofalángica de la mano izquierda de semanas de evolución. Con el diagnós - tico final de osteocondritis disecante realizamos una resección del fragmento libre asociadas a perforaciones con aguja fina. Tras el primer año de seguimiento el paciente se encuentra asintomático y se observa remodelación casi completa de la superficie articular.Ostheocondritis in the hand is a rare process. Only two cases were reported in the previous litera - ture. In this report we present a 10 years old boy with pain and a few functional limitation in second metacarpal phalangeal joint for weeks. With the final diagnosis of osteochondritis dissecans we performed surgery. Intraope - ratively the cartilage flap was removed and some drilling was realized. Before one year the patient was asympto - matic and we observed an improvement of articular surface

Osteoporosis transitoria de rodilla en el embarazo

La osteoporosis transitoria o síndrome de edema óseo transitorio es una enfermedad poco frecuente y autolimitada que puede afectar a la mujer embarazada. La etiología es desconocida y su localización más frecuente es la cadera. Presentamos un caso de osteoporosis transitoria de rodilla durante el embarazo, con resolución clínica y radiológica completa tras 10 meses de evolución.Transient osteoporosis or transient bone edema syndrome is a rare, self-limiting disease that can affect pregnant women. The etiology is unknown and most common location is the hips. We present a case of tran - sient osteoporosis of the knee during pregnancy, with complete clinical and radiological resolution after 10 months

Survival of several Rhizobium/Bradyrhizobium strains on different inoculant formulations and inoculated seeds

The effect of a variety factors on the survival of several rhizobia strains on inoculants and inoculated seeds has been evaluated. Since the rhizobia strains showed different cell-density-evolution patterns on peat-based inoculants and on inoculated seeds, several inoculant formulations with highly effective Rhizobium/ Bradyrhizobium strains (for Lupinus, Hedysarum, Phaseolus and Glycine max. ) were monitored under the following storage conditions: (a) the inoculants were kept refrigerated (at 4°C), or (b) at room temperature (25°C). The effect of water content (30–50%, w/w) in the inoculants as well as that of several seed-coating adhesives were also investigated. Alternative carriers including perlite and vermiculite were tested. For all of the strains, survival on sterile peat-based inoculants was higher than on the corresponding unsterile peat formulation; for the latter, refrigerated storage conditions are recommended to ensure high bacterial densities. The water content of the inoculants had a differential effect on strain survival depending on the sterility of the peat, such that a high water content was more detrimental when unsterilized peat was employed. The best adherent for rhizobia survival was a gum arabic/water solution. Perlite was as effective as peat in maintaining a high population of rhizobia, at least for 6 months of storage

El abordaje transapofisario en las fracturas complejas del extremo distal femoral y proximal tibial

Los autores presentan las ventajas e inconvenientes, así como los distintos pasos de la técnica quirúrgica en el abordaje transapofisario, para resolver aquellas fracturas complejas tanto del extremo distal femoral como del extremo proximal tibial, en donde una amplia exposición del foco fracturario es imprescindible para lograr la restauración lo más anatómica posible de la superficie articular, que le permita a los pacientes reiniciar una movilización articular precoz. Consideran a este tipo de abordaje quirúrgico como muy beneficioso e imprescindible en estas fracturas tan complejas, presentando su experiencia al respecto.The authors show the advantages and disadvantages, as well as somo differents points of the surgical technique at the transapophyseal approach, for complex fractures of the distal end of the femur and proximal tibial plateau, when an extensible exposur e is essential to obtain an anatomic restitution of the articular surface, and to allow to the patient to mobilize the joint at once. They consider this type of surgical approach as very beneficial and essentia] in these fractures so complex. They present their experience

Study of the soils of the Ebro Valley. I. Provinces of Logroño and Navarra

Final technical reportThe study of the soils of the provinces of Navarra and Logroño, both of which belong to the Ebro river basin, comprises two essential parts: on. the one hand, the mapping of the soils of the above mentioned provinces and, on the other, the preparation of the corresponding explicative report.The research reported in this document has been made possible through the support and sponsorship of the U.S. Department of the Army through its European Research Office. Contract No. DA-91-591-EUC-1085 1st. March 1959 to 30th February 1960.N

Study of the physical properties of soils through interpretation of aerial photographs

Final technical reportThe purpose of the research work proposed is the study of the physical properties of the soils by means of the interpretation of aerial photographs. This study is to be carried out in two years and thus it is not possible to give definite conclusions at the end of the first year, although the results we have obtained are highly satisfactory. In our opinion and after the experience of the first year, the working problem of the study of the physical properties of the soils through aerial photographs, can be examined from two different aspects. The first of them could be called the "deductive" method and consists in acquiring knowledge of the physical properties of the soils by means of sucoessive interpretations of aerial photographs; through photointerpretation we study the physical Geography of an area, its hydrographic net, natural vegetation and .man-introduced cultivations, the forms of erosion end the nature of the geological material, All these interpretations, together with the clitmate, allow to "deduce" the nature of the soils of that area, as all the pedological processes which the different geological materials have undergone can be know perfectly well, which also shows the intensity of physical and chemical desintegration of the materials that form the starting point of soil formation.The research reported in this document has been made possible through the support and sponsorship of the U.S. Department of the Army through its European Research Office.Contract No. DA-91-591-EUC-2652 1st. April 1963 to 31th March 1964.N

Unexpected dielectric response in lead zirconate titanate ceramics: The role of ferroelectric domain wall pinning effects

Temperature dependent dielectric response has been measured in Pb(Zr1-xTix)O-3 ceramics. Samples of different compositions (x=0.40, 0.47, and 0.60), pure and doped with Nb-or Fe, were studied at temperatures between 15 and 700 K and in the frequency range from 100 Hz to 1 MHz. Unexpected dielectric behavior has been found around room temperature. Anomalous temperature dependent permittivity is observed in pure and Fe-doped samples but not in Nb-doped samples. The anomaly appears related to the presence of oxygen vacancies but not on the sample crystallographic phase. The authors suggest that the anomaly may be a manifestation of the domain wall pinning effect. (C) 2007 American Institute of Physics.Peer ReviewedPostprint (published version

Polyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults

Background: Adults with chronic Trypanosoma cruzi exhibit a poorly functional T cell compartment, characterized by monofunctional (IFN-γ-only secreting) parasite-specific T cells and increased levels of terminally differentiated T cells. It is possible that persistent infection and/or sustained exposure to parasites antigens may lead to a progressive loss of function of the immune T cells. Methodology/Principal Findings: To test this hypothesis, the quality and magnitude of T. cruzi-specific T cell responses were evaluated in T. cruzi-infected children and compared with long-term T. cruzi-infected adults with no evidence of heart failure. The phenotype of CD4+ T cells was also assessed in T. cruzi-infected children and uninfected controls. Simultaneous secretion of IFN-γ and IL-2 measured by ELISPOT assays in response to T. cruzi antigens was prevalent among T. cruzi-infected children. Flow cytometric analysis of co-expression profiles of CD4+ T cells with the ability to produce IFN-γ, TNF-α, or to express the co-stimulatory molecule CD154 in response to T. cruzi showed polyfunctional T cell responses in most T. cruzi-infected children. Monofunctional T cell responses and an absence of CD4+TNF-α+-secreting T cells were observed in T. cruzi-infected adults. A relatively high degree of activation and differentiation of CD4+ T cells was evident in T. cruzi-infected children. Conclusions/Significance: Our observations are compatible with our initial hypothesis that persistent T. cruzi infection promotes eventual exhaustion of immune system, which might contribute to disease progression in long-term infected subjects.Fil: Albareda, María Cecilia. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: de Rissio, Ana María. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; ArgentinaFil: Tomas, Gonzalo. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; ArgentinaFil: Serjan, Alicia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Juan A. Fernández"; ArgentinaFil: Alvarez, María Gabriela. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Viotti, Rodolfo Jorge. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Fichera, Laura Edith. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Esteva, Mónica Inés. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; ArgentinaFil: Potente, Daniel Fernando. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Armenti, Alejandro. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Tarleton, Rick L.. University of Georgia; Estados UnidosFil: Laucella, Susana Adriana. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

The Incremental Cooperative Design of Preventive Healthcare Networks

This document is the Accepted Manuscript version of the following article: Soheil Davari, 'The incremental cooperative design of preventive healthcare networks', Annals of Operations Research, first published online 27 June 2017. Under embargo. Embargo end date: 27 June 2018. The final publication is available at Springer via http://dx.doi.org/10.1007/s10479-017-2569-1.In the Preventive Healthcare Network Design Problem (PHNDP), one seeks to locate facilities in a way that the uptake of services is maximised given certain constraints such as congestion considerations. We introduce the incremental and cooperative version of the problem, IC-PHNDP for short, in which facilities are added incrementally to the network (one at a time), contributing to the service levels. We first develop a general non-linear model of this problem and then present a method to make it linear. As the problem is of a combinatorial nature, an efficient Variable Neighbourhood Search (VNS) algorithm is proposed to solve it. In order to gain insight into the problem, the computational studies were performed with randomly generated instances of different settings. Results clearly show that VNS performs well in solving IC-PHNDP with errors not more than 1.54%.Peer reviewe