9 research outputs found
Effect of different genetics variants: CYP2C9*2, CYP2C9*3 of cytochrome P-450 CYP2C9 and 1639G>A of the VKORC1 gene; On acenocoumarol requirement in Moroccan patients
P101 Effect of different genetic variants (2C9*2, 2C9*3 of cytochrome P-450 CYP2C9 and −1639G>A of the VKORC1 gene) on acenocoumarol requirement in Moroccan patients
Diverticule congénital isolé du ventricule gauche découvert à l’âge adulte : apport de l’imagerie
Le diverticule cardiaque est une malformation congénitale rare, sa découverte à l’âge adulte est encore plus rare. Il est souvent associé à d’autres diverticules thoraco-abdominaux, et rarement isolé. Le diagnostic repose sur l’échocardiographie. Par ailleurs, l’imagerie par résonance magnétique (IRM) permet une analyse plus fine du diverticule, de sa topographie et ses rapports avec les structures vasculaires et cardiaques, elle a largement remplacé la ventriculographie. Nous rapportons dans cet article le cas d’un patient de 36 ans dont le diagnostic de diverticule a été posé par l’échocardiographie transthoracique (ETT) lors d’un bilan de dyspnée, cet examen a aussi objectivé une insuffisance mitrale (IM) par déformation et dilatation de l’anneau mitral. Le bilan radiologique a été complété par une échocardiographie transœsophagienne (ETO), et une IRM. Le traitement chirurgical a consisté en la fermeture chirurgicale du diverticule avec annuloplastie mitrale
Should transcatheter closure of atrial septal defects with inferior-posterior deficient rim still be attempted?
International audienceBackground: Transcatheter closure for atrial septal defect (ASD) with inferior-posterior rim deficiency hasbeen scarcely reported with proper identification of the indications and limits. We aimed to assess the safetyand feasibility of transcatheter closure of ASDs with deficient rims, paying particular attention to cases withinferior-posterior rim deficiency.Methods: From January 2008 to January 2013, 241 patients underwent transcatheter ASD closure,including 50 cases (20.7%) with deficient rims, other than the anterior-superior one. Eighteen patients(12 females) presented inferior-posterior rim deficiency. Their median age was 8 (1.4–85) years and theirmedian weight was 24 [9–97] kg. Transcatheter closure was performed in all cases under transesophageal echocardiography (TEE) guidance in children and intracardiac echocardiography (ICE) guidance in adults.Results: Out of 18 patients with inferior-posterior rim deficiency, only 8 underwent successful immediate transcatheter closure. Four cases failed to be closed. Major complications occurred in 6 patients, including 4 device embolizations, 1 pericardial effusion and 1 complete atrioventricular block that resolved after surgical removal of the device. During a median follow up of 54±13 months, a residual right-to-left shuntwas documented in 2 more cases, requiring surgery in one case because of cyanosis. Transcatheter closure was successfully performed in the rest of the 223 patients, including in the 32 cases with deficient rims other than inferior-posterior.Conclusions: Transcatheter closure of ASDs with inferior-posterior rim deficiency cannot b
Chemical composition, vasorelaxant, antioxidant and antiplatelet effects of essential oil of Artemisia campestris L. from Oriental Morocco
Dysphania ambrosioides (L.) Mosyakin & Clemants
Dysphania ambrosioides (L.) Mosyakin & Clemants (= Chenopodium ambrosioides L.) is an American aromatic species used as medicinal and culinary purposes since pre-Columbian times by Aztecs and Mayans in Mesoamerica (where is called epazote) and Andean communities and many others in South America (where is better known as paico). Currently, it is globally known by a wide diversity of cultures around the world, due to its cultivation and naturalization. Its uses are currently widespread in pluricultural contexts, by means the commercial circuits and mass media, especially the Internet. The main active constituents are essential oils, to which owes its aroma and flavor. It is toxic in high doses, but safe if is consumed in appropriated concentrations. The most widespread folk therapeutic use is as antiparasitic (anthelmintic, antimicrobial), and it is also employed against gastrointestinal disorders, as hypotensive, antipyretic, vulnerary, analgesic, anti-inflammatory, antitumor, sedative and anxiolytic, among others, many of which have been evaluated scientifically. The researches on its anticancer activity are very promising.Fil: Hurrell, Julio Alberto. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Laboratorio de Etnobotánica y Botánica Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentin
